A chemostat culture as a tool for the improvement of a recombinant E. coli strain over-producing penicillin G acylase

Biotechnology and Bioengineering

Volumn 75, Issue 1, 2001, Pages 46-52

  Converti, Attilio ^a   Domnguez, Jos Manuel ^b  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF VIGO   (Spain)

Author keywords

Chemostat culture; Escherichia coli; Penicillin G acylase; Recombinant strain adaptation

Indexed keywords

CARBON; CELL CULTURE; ENZYMES; ESCHERICHIA COLI; GENES; NITROGEN; ORGANIC ACIDS; STRAIN;

BIOSYNTHETIC CAPACITY;

CHEMOSTATS;

NITROGEN; PENICILLIN AMIDASE; PENICILLIN G ACYLASE; PHENYLACETIC ACID; PHENYLACETIC ACID AMIDE; UNCLASSIFIED DRUG;

ADAPTATION; ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL GROWTH; BACTERIUM CULTURE; BIOSYNTHESIS; CHEMOSTAT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME SYNTHESIS; ESCHERICHIA COLI; FRAMESHIFT MUTATION; GENETIC RECOMBINATION; GROWTH RATE; NONHUMAN; PLASMID; STRAIN DIFFERENCE;

CULTURE MEDIA; DNA, RECOMBINANT; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; NITROGEN; PENICILLIN AMIDASE; PHENYLACETATES; PLASMIDS;

ESCHERICHIA COLI; PAA;

EID: 0035812879     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.1163     Document Type: Article

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