FR226807: A potent and selective phosphodiesterase type 5 inhibitor

European Journal of Pharmacology

Volumn 428, Issue 2, 2001, Pages 295-302

  Hosogai, Naomi ^a   Hamada, Kaori ^a   Tomita, Masayuki ^a   Nagashima, Akira ^a   Takahashi, Tokiko ^a   Sekizawa, Toshihiro ^a   Mizutani, Tsuyoshi ^a   Urano, Yasuharu ^a   Kuroda, Akio ^a   Sawada, Kozo ^a   Ozaki, Tohru ^a   Seki, Jiro ^a   Goto, Toshio ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

FR226807; Penile erection; Phosphodiesterase type 5 inhibitor

Indexed keywords

CYCLIC GMP; FR 226807; N (3,4 DIMETHOXYBENZYL) 2 [[2 HYDROXY 1 METHYLETHYL]AMINO] 5 NITROBENZAMIDE; PHOSPHODIESTERASE; PHOSPHODIESTERASE I; PHOSPHODIESTERASE III; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE TYPE 2; PHOSPHODIESTERASE TYPE VI; PHOSPHODIESTERASE V; SILDENAFIL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS CAVERNOSUM; DOG; DRUG EFFECT; DRUG POTENCY; DRUG SELECTIVITY; ELECTRIC FIELD; ENZYME INHIBITION; ERECTILE DYSFUNCTION; IC 50; MALE; MUSCLE RELAXATION; NONHUMAN; PELVIC NERVE; PENIS ERECTION; PRIORITY JOURNAL; RABBIT; THROMBOCYTE;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ANIMALS; BENZAMIDES; BLOOD PRESSURE; CYCLIC GMP; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; HUMANS; ISOENZYMES; MALE; MUSCLE CONTRACTION; MUSCLE RELAXATION; PENIS; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PIPERAZINES; PRESSURE; RABBITS; TIME FACTORS;

EID: 0035812664     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)01345-0     Document Type: Article

References (20)

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