Localization of human immunodeficiency virus type 1 Gag and Env at the plasma membrane by confocal imaging

Journal of Virology

Volumn 74, Issue 18, 2000, Pages 8670-8679

  Hermida Matsumoto, L ^a   Resh, M D ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; VIRUS ENVELOPE PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONFOCAL MICROSCOPY; GOLGI COMPLEX; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTATION; MYRISTYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; VIRUS ENVELOPE; VIRUS PARTICLE;

ANIMALS; BACTERIAL PROTEINS; CELL FRACTIONATION; CELL MEMBRANE; CENTRIFUGATION, DENSITY GRADIENT; COS CELLS; FLUORESCENT ANTIBODY TECHNIQUE; GENE PRODUCTS, ENV; GENE PRODUCTS, GAG; GOLGI APPARATUS; HELA CELLS; HIV-1; HUMANS; MICROSCOPY, CONFOCAL; MYRISTIC ACID; PROTEIN PRECURSORS; PROTEIN STRUCTURE, TERTIARY; STREPTOLYSINS;

EID: 0033856584     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.18.8670-8679.2000     Document Type: Article

References (42)

1. Myristoylation-dependent replication and assembly of human immunodeficiency virus 1
2. Human immunodeficiency virus type 1 Gag polyprotein multimerization requires the nucleocapsid domain and RNA and is promoted by the capsiddimer interface and the basic region of matrix protein
3. Direct interaction between the envelope and matrix proteins of HIV-1
4. Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein
5. A large deletion in the matrix domain of the human immunodeficiency virus gag gene redirects virus particle assembly from the plasma membrane to the endoplasmic reticulum
6. HIV-1 gag proteins: Diverse functions in the virus life cycle
7. Virion incorporation of envelope glycoproteins with long but not short cytoplasmic tails is blocked by specific, single amino acid substitutions in the human immunodeficiency virus type 1 matrix
8. Cryo-electron microscopy reveals ordered domains in the immature HIV-1 particle
9. Recent advances and remaining problems in HIV assembly
10. Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins
11. Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1
12. Human immunodeficiency virus type 1 protease triggers a myristoyl switch that modulates membrane binding of Pr55(Gag) and p17MA
13. Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: Implications for membrane association and assembly
14. Analysis of protein expression and virus-like particle formation in mammalian cell lines stably expressing HIV-1 gag and env gene products with or without active HIV proteinase
15. Formation of virus assembly intermediate complexes in the cytoplasm by wild-type and assembly-defective mutant human immunodeficiency virus type 1 and their association with membranes
16. The intracytoplasmic domain of gp41 mediates polarized budding of human immunodeficiency virus type 1 in MDCK cells
17. Rescue of human immunodeficiency virus type 1 matrix protein mutants by envelope glycoproteins with short cytoplasmic domains
18. Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis
19. Three-dimensional structure of the human immunodeficiency virus type 1 matrix protein
20. Comparison of the NMR and X-ray structures of the HIV-1 matrix protein: Evidence for conformational changes during viral assembly
21. Electrostatics and the membrane association of Src: Theory and experiment
22. p80/85 Cortactin associates with the Src SH2 domain and colocalizes with v-Src in transformed cells
23. Binding of human immunodeficiency virus type 1 Gag to membrane: Role of the matrix amino terminus
24. Role of the Gag matrix domain in targeting human immunodeficiency virus type 1 assembly
25. Opposing effects of human immunodeficiency virus type 1 matrix mutations support a myristyl switch model of Gag membrane targeting
26. Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes
27. Efficient HIV-1 replication can occur in the absence of the viral matrix protein
28. Fatty acylation of proteins: New insights into membrane targeting of myristoylated and palmitoylated proteins
29. Molecular events in the assembly of retrovirus particles
30. The I domain is required for efficient plasma membrane binding of human immunodeficiency virus type 1 Pr55(Gag)
31. Membrane-induced alterations in HIV-1 Gag and matrix protein-protein interactions
32. Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Rev-independent gag expression
33. Amino-terminal basic residues of Src mediate membrane binding through electrostatic interaction with acidic phospholipids
34. Membrane binding of human immunodeficiency virus type 1 matrix protein in vivo supports a conformational myristyl switch mechanism
35. Cellular functions regulated by Src family kinases
36. Kinetic analysis of human immunodeficiency virus type 1 assembly reveals the presence of sequential intermediates
37. Biochemical and immunological analysis of human immunodeficiency virus gag gene products p17 and p24
38. Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromo-palmitate and polyunsaturated fatty acids
39. Specific interactions between retrovirus Env and Gag proteins in rat neurons
40. The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions
41. Mutations in the N-terminal region of human immunodeficiency virus type 1 matrix protein block intra-cellular transport of the Gag precursor
42. Identification of a membrane-binding domain within the amino-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic phospholipids