An improved synthesis of N-aryl-hydantoin LFA-1 antagonists via the enantiospecific alkylation of an isobutyraldehyde-derived imidazolidinone template

Tetrahedron Asymmetry

Volumn 12, Issue 1, 2001, Pages 101-104

  Frutos, Rogelio P ^a   Stehle, Sandra ^a   Nummy, Laurence ^a   Yee, Nathan ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIRT 377; HYDANTOIN DERIVATIVE; IMIDAZOLE DERIVATIVE; IMIDAZOLIDINONE; ISOBUTYRALDEHYDE; N ARYL HYDANTOIN LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1 ANTAGONIST; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; DRUG HYDROLYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TRANSFORMATION; ENANTIOMER; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOSPECIFICITY;

EID: 0035808903     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(01)00009-X     Document Type: Article

References (21)