Structure-activity relationships of phenylcyclohexene and biphenyl antitubulin compounds against plant and mammalian cells

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 11, 2001, Pages 1393-1396

  Young, David H ^a   Tice, Colin M ^a   Michelotti, Enrique L ^a   Roemmele, Renee C ^a   Slawecki, Richard A ^a   Rubio, Fernando M ^a   Rolling, Judith A ^a  

^a ROHM AND HAAS COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,4,4' TETRAMETHOXY 2' METHYLBIPHENYL; 4 NITRO 5 (2,3,4 TRIMETHOXYPHENYL)CYCLOHEXENE; BIPHENYL DERIVATIVE; COLCHICINE; CYCLOHEXENE DERIVATIVE; PHENYLCYCLOHEXENE DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CANCER INHIBITION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG POTENCY; DRUG STRUCTURE; MAMMAL CELL; NONHUMAN; PLANT CELL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; COLCHICINE; CYCLOHEXANES; CYCLOHEXENES; HERBICIDES; NITRO COMPOUNDS; PLANT ROOTS; PLANTS, TOXIC; STRUCTURE-ACTIVITY RELATIONSHIP; TOBACCO; TUBULIN; TUBULIN MODULATORS; TUMOR CELLS, CULTURED;

BOVINAE; MAMMALIA;

EID: 0035806226     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00246-3     Document Type: Article

References (20)