The dynamics of blood-brain barrier breakdown in an experimental model of glial cell degeneration

Neuroscience

Volumn 103, Issue 4, 2001, Pages 873-883

  Guerin C J ^a   Nolan, C C ^a   Mavroudis, G ^a   Lister, T ^a   Davidson, G M ^a   Holton, J L ^a   Ray, D E ^a  

^a MRC TOXICOLOGY UNIT   (United Kingdom)

Author keywords

Blood brain barrier; CNS; Confocal microscopy; Glial cells; Immunohistochemistry; Vascular permeability

Indexed keywords

1,3 DINITROBENZENE; ANTIBODY; DEXTRAN; RHODAMINE; TRACER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BLOOD VESSEL PERMEABILITY; BRAIN BLOOD VESSEL; CELL ACTIVATION; CELL INVASION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISEASE MODEL; GLIA CELL; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MOLECULAR WEIGHT; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BLOOD-BRAIN BARRIER; CAPILLARY PERMEABILITY; DEXTRANS; DINITROBENZENES; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, CONFOCAL; NERVE DEGENERATION; NEUROGLIA; RATS; RATS, INBRED F344; TIME FACTORS;

EID: 0035804783     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(01)00015-X     Document Type: Article

References (26)

1. Astrocyte-endothelial interaction: Physiology and pathology
2. Is the pial microvessel a good model for blood-brain barrier studies?
3. Evidence of blood-brain barrier dysfunction in human cerebral malaria
4. Blood-brain barrier disruption in human immunodeficiency virus-1 encephalitis
5. An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro
6. Die äussere und innere Sekretion des gesunden und kranken Organismus in Lichte der "vitalen Färbung"
7. The circulatory system
8. Glutathione depletion increases brain susceptibility to 1,3-dinitrobenzene neurotoxicity
9. Spinal cord compression injury in guinea pigs: Structural changes of endothelium and its perivascular cell associations after blood-brain barrier breakdown and repair
10. Astrocytes induce blood-brain barrier properties in endothelial cells
11. Neuronal cell death in Wernicke's encephalopathy: Pathophysiologic mechanisms and implications for PET imaging
12. Sucrose and insulin space measurements of cerebral cortex in four mammalian species
13. Zur Lehre der Zerebrospinalflüssigkeit
14. Inhibition of glial scarring in the injured rat brain by a recombinant human monoclonal antibody to transforming growth factor-β2
15. Traumatic brain injury in the rat: Characterization of a midline fluid-percussion model
16. Impaired induction of blood-brain barrier properties in aortic endothelial cells by astrocytes from GFAP-deficient mice
17. 1,3-Dinitrobenzene-induced encephalopathy in rats
18. Osmotic opening of the blood-brain barrier in the rhesus monkey without measurable brain edema
19. Vascular factors in the neurotoxic damage caused by 1,3-dinitrobenzene in the rat
20. An in vitro study of 1,3-dinitrobenzene toxicity on the cellular components of the blood-brain barrier, astrocytes and endothelial cells
21. The pathophysiology of multiple sclerosis: The mechanisms underlying the production of symptoms and the natural history of the disease
22. A dynamic model of the blood-brain barrier in vitro
23. Pathways of fluid drainage from the brain-morphological aspects and immunological significance in rat and man
24. Pharmacokinetic factors and concentration-time threshold in 1,3-dinitrobenzene-induced neurotoxicity
25. 32P-phosphate in brain swelling induced by cold injury
26. 3H]inulin after osmotic opening in the rat