SCOPUS 정보 검색 플랫폼

Volumn 414, Issue 2-3, 2001, Pages 233-243

Population pharmacokinetic-pharmacodynamic modelling of S 15535, a 5-HT1A receptor agonist, using a behavioural model in rats

(7) Vis, Peter a,d Della Pasqua, Oscar b Kruk, Menno b Martin, Delphine a Mocaër, Elisabeth c Danhof, Meindert b Jochemsen, Roeline c

a Servier Research and Development (United Kingdom)

b LEIDEN UNIVERSITY (Netherlands)

c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER (France)

d PHARSIGHT CORPORATION (United States)

Author keywords

Behavioural pharmacology; Buspirone; Drug development; NONMEM (non linear mixed effects modelling); Pharmacokinetic pharmacodynamic modelling; S 15535; S 32784

Indexed keywords

1 (1,4 BENZODIOXAN 5 YL) 4 (2 INDANYL)PIPERAZINE; 1 (BENZODIOXAN 5 YL) 4 (5 HYDROXYINDAN 2 YL)PIPERAZINE; BUSPIRONE; DRUG METABOLITE; DUPHAR; PIPERAZINE DERIVATIVE; PLASMA PROTEIN; S 32784; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANXIETY; ARTICLE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG POTENCY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MODEL; NONHUMAN; PRIORITY JOURNAL; RAT; TRANQUILIZING ACTIVITY; VOCALIZATION;

ANIMALS; ANTI-ANXIETY AGENTS; BUSPIRONE; MALE; NONLINEAR DYNAMICS; PIPERAZINES; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN AGONISTS; VOCALIZATION, ANIMAL;

EID: 0035793983 PISSN: 00142999 EISSN: None Source Type: Journal
DOI: 10.1016/S0014-2999(01)00801-9 Document Type: Article

Times cited : (9)

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