A single exposure to morphine induces long-lasting behavioural and neurochemical sensitization in rats

European Journal of Neuroscience

Volumn 14, Issue 9, 2001, Pages 1533-1538

  Vanderschuren, Louk J M J ^a   De Vries, Taco J ^a   Wardeh, George ^a   Hogenboom, François A C M ^a   Schoffelmeer, Anton N M ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Acetylcholine release; Amphetamine; Caudate putamen; Dopamine release; Locomotion; Nucleus accumbens

Indexed keywords

ACETYLCHOLINE; AMPHETAMINE; DOPAMINE; MORPHINE; OPIATE DERIVATIVE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CAUDATE NUCLEUS; CONTROLLED STUDY; ELECTROSTIMULATION; EVOKED RESPONSE; LOCOMOTION; MALE; MORPHINE ADDICTION; NEUROCHEMISTRY; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PSYCHOMOTOR ACTIVITY; PUTAMEN; RAT; SENSITIZATION;

ACETYLCHOLINE; AMPHETAMINE; ANIMALS; BRAIN CHEMISTRY; CORPUS STRIATUM; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; DRUG TOLERANCE; MALE; MORPHINE; MORPHINE DEPENDENCE; MOTOR ACTIVITY; NEOSTRIATUM; NEUROTRANSMITTER AGENTS; NUCLEUS ACCUMBENS; PRESYNAPTIC TERMINALS; RATS; RATS, WISTAR; TRITIUM;

EID: 0035783433     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0953-816X.2001.01775.x     Document Type: Article

References (37)

1. Babbini, M., Gaiardi, M. & Bartoletti, M. (1975) Persistence of chronic morphine effects upon activity in rats 8 months after ceasing the treatment. Neuropharmacology, 14, 611-614.
2. Berke, J.D. & Hyman, S.E. (2000) Addiction, dopamine, and the molecular mechanisms of memory. Neuron, 25, 515-532.
3. Bickerdike, M.J. & Abercrombie, E.D. (1997) Striatal acetylcholine release correlates with behavioral sensitization in rats withdrawn from chronic amphetamine. J. Pharmacol. Exp. Ther., 282, 818-826.
4. Broekkamp, C.L.E., Phillips, A.G. & Cools, A.R. (1979) Stimulant effects of enkephalin microinjection into the dopaminergic A10 area. Nature, 278, 560-562.
5. Cochin, J. & Kornetsky, C. (1964) Development and loss of tolerance to morphine in the rat after single and multiple injections. J. Pharmacol. Exp. Ther., 145, 1-10.
6. De Vries, T.J., Schoffelmeer, A.N.M., Binnekade, R., Mulder, A.H. & Vanderschuren, L.J.M.J. (1998) Drug-induced reinstatement of heroinand cocaine-seeking behaviour following long-term extinction is associated with expression of behavioural sensitization. Eur. J. Neurosci., 10, 3565-3571.
7. Deroche, V., Le Moal, M. & Piazza, P.V. (1999) Cocaine self-administration increases the incentive motivational properties of the drug in rats. Eur. J. Neurosci., 11, 2731-2736.
8. Di Chiara, G., Morelli, M. & Consolo, S. (1994) Modulatory functions of neurotransmitters in the striatum: ACh/dopamine/NMDA interactions. Trends Neurosci., 17, 228-233.
9. Jeziorski, M., White, F.J. & Wolf, M.E. (1994) MK-801 prevents the development of behavioral sensitization during repeated morphine administration. Synapse, 16, 137-147.
10. Johnson, K., Churchill, L., Klitenick, M.A., Hooks, M.S. & Kalivas, P.W. (1996) Involvement of the ventral tegmental area in locomotion elicited from the nucleus accumbens or ventral pallidum. J. Pharmacol. Exp. Ther., 277, 1122-1131.
11. Kalivas, P.W. & Alesdatter, J.E. (1993) Involvement of N-methyl-D-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine. J. Pharmacol. Exp. Ther., 267, 486-495.
12. Kalivas, P.W., Churchill, L. & Klitenick, M.A. (1993) The circuitry mediating the translation of motivational stimuli into adaptive motor responses. In: Kalivas, P.W. & Barnes, C.D. (eds), Limbic Motor Circuits and Neuropsychiatry. CRC Press, Boca Raton, pp. 237-287.
13. Kalivas, P.W., Widerlöv, E., Stanley, D., Breese, G. & Prange, A.J. Jr (1983) Enkephalin action on the mesolimbic system: A dopamine-dependent and a dopamine-independent increase in locomotor activity. J. Pharmacol. Exp. Ther., 227, 229-237.
14. Klitenick, M.A. & Kalivas, P.W. (1994) Behavioral and neurochemical studies of opioid effects in the pedunculopontine nucleus and mediodorsal thalamus. J. Pharmacol. Exp. Ther., 269, 437-448.
15. Koob, G.F. (1992) Drugs of abuse: Anatomy, pharmacology and function of reward pathways. Trends Pharmacol. Sci., 13, 177-184.
16. Marshall, D.L., Redfern, P.H. & Wonnacott, S. (1997) Presynaptic nicotinic modulation of dopamine release in the three ascending pathways studied by in vivo microdialysis: Comparison of naive and chronic nicotine-treated rats. J. Neurochem., 68, 1511-1519.
17. Mucha, R.F., Van der Kooy, D., O'Shaughnessy, M. & Bucenieks, P. (1982) Drug reinforcement studies by the use of place conditioning in rat. Brain Res., 243, 91-105.
18. Nestby, P., Vanderschuren, L.J.M.J., De Vries, T.J., Hogenboom, F., Wardeh, G., Mulder, A.H. & Schoffelmeer, A.N.M. (1997) Ethanol, like psychostimulants and morphine, causes long-lasting hyperreactivity of dopamine and acetylcholine neurons of rat nucleus accumbens: Possible role in behavioural sensitization. Psychopharmacology, 133, 69-76.
19. Nestler, E.J. (2001) Molecular basis of long-term plasticity underlying addiction. Nature Rev. Neurosci., 2, 119-128.
20. Pert, A. & Sivit, C. (1979) Neuroanatomical focus for morphine and enkephalin-induced hypermotility. Nature, 265, 645-647.
21. Post, R.M. (1980) Intermittent versus continuous stimulation: Effect of time interval on the development of sensitization or tolerance. Life Sci., 26, 1275-1282.
22. Reid, M.S., Fox, L., Ho, L.B. & Berger, S.P. (2000) Nicotine stimulation of extracellular glutamate levels in the nucleus accumbens: Neuropharmacological characterization. Synapse, 35, 129-136.
23. Robbins, T.W. & Everitt, B.J. (1996) Neurobehavioural mechanisms of reward and motivation. Curr. Opin. Neurobiol., 6, 228-236.
24. Robinson, T.E. & Becker, J.B. (1986) Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis. Brain Res. Rev., 11, 157-198.
25. Robinson, T.E., Becker, J.B. & Presty, S.K. (1982) Long-term facilitation of amphetamine-induced rotational behavior and striatal dopamine release produced by a single exposure to amphetamine: Sex differences. Brain Res., 253, 231-241.
26. Robinson, T.E. & Berridge, K.C. (2001) Incentive-sensitization and addiction. Addiction, 96, 103-114.
27. 2 receptors. Synapse, 17, 190-195.
28. Schoffelmeer, A.N.M., Nestby, P., Tjon, G.H.K., Wardeh, G., De Vries, T.J., Vanderschuren, L.J.M.J. & Mulder, A.H. (1995) Intermittent morphine treatment causes a protracted increase in cholinergic striatal neurotransmission measured ex vivo. Eur. J. Pharmacol., 286, 311-314.
29. Schoffelmeer, A.N.M., Wardeh, G. & Vanderschuren, L.J.M.J. (2001) Morphine acutely and persistently attenuates nonvesicular GABA release in rat nucleus accumbens. Synapse, 42, 87-94.
30. Smolders, I., Bogaert, L., Ebinger, G. & Michotte, Y. (1997) Muscarinic modulation of striatal dopamine, glutamate, and GABA release, as measured with in vivo microdialysis. J. Neurochem., 68, 1942-1948.
31. Stewart, J. & Badiani, A. (1993) Tolerance and sensitization to the behavioral effects of drugs. Behav. Pharmacol., 4, 289-312.
32. Van Ree, J.M., Gerrits, M.A.F.M. & Vanderschuren, L.J.M.J. (1999) Opioids, reward and addiction: An encounter of biology, psychology and medicine. Pharmacol. Rev., 51, 341-396.
33. Vanderschuren, L.J.M.J., De Vries, T.J., Wardeh, G., Hogenboom, F. & Schoffelmeer, A.N.M. (2000) A single exposure to morphine causes longlasting sensitization of the psychomotor effect of amphetamine and hyperreactivity of nucleus accumbens dopamine and acetylcholine nerve terminals in rats. Soc. Neurosci. Abstr., 26, 2081.
34. Vanderschuren, L.J.M.J. & Kalivas, P.W. (2000) Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: A critical review of preclinical studies. Psychopharmacology, 151, 99-120.
35. Vanderschuren, L.J.M.J., Schmidt, E.D., De Vries, T.J., Van Moorsel, C.A.P., Tilders, F.J.H. & Schoffelmeer, A.N.M. (1999a) A single exposure to amphetamine is sufficient to induce long-term behavioral, neuroendocrine and neurochemical sensitization in rats. J. Neurosci., 19, 9579-9586.
36. Vanderschuren, L.J.M.J., Schoffelmeer, A.N.M., Mulder, A.H. & De Vries, T.J. (1999b) Lack of cross-sensitization of the locomotor effects of morphine in amphetamine-treated rats. Neuropsychopharmacology, 21, 550-559.
37. Vanderschuren, L.J.M.J., Tjon, G.H.K., Nestby, P., Mulder, A.H., Schoffelmeer, A.N.M. & De Vries, T.J. (1997) Morphine-induced long term sensitization to the locomotor effects of morphine and amphetamine depends on the temporal pattern of the pretreatment regimen. Psychopharmacology, 131, 115-122.