Genetic polymorphisms and lipid response to dietary changes in humans

European Journal of Clinical Investigation

Volumn 31, Issue 11, 2001, Pages 950-957

  Weggemans, R M ^a   Zock, P L ^b   Ordovas, J M ^c   Ramos Galluzzi, J ^c   Katan, M B ^a,b  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b TOP INSTITUTE FOOD AND NUTRITION   (Netherlands)

^c TUFTS UNIVERSITY   (United States)

Author keywords

Cafestol; Cholesterol; Genetic polymorphisms; Lipids; Saturated fat; trans fat

Indexed keywords

APOLIPOPROTEIN A4; CAFESTOL; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEIN; DITERPENE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SATURATED FATTY ACID;

ADULT; ALLELE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SEX DIFFERENCE;

ADOLESCENT; ADULT; APOLIPOPROTEINS A; CHOLESTEROL; COFFEE; DIET; DIETARY FATS; DITERPENES; FEMALE; GENOTYPE; HUMANS; LIPID METABOLISM; MALE; POLYMORPHISM, GENETIC;

EID: 0035780207     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.2001.00906.x     Document Type: Article

References (39)

1. Katan MB, Beynen AC, de Vries JH, Nobels A. Existence of consistent hypo- and hyperresponders to dietary cholesterol in man. Am J Epidemiol 1986;123:221-34.
2. Ordovas JM, Lopez-Miranda J, Mata P, Perez-Jimenez F, Lichtenstein AH, Schaefer EJ. Gene-diet interaction in determining plasma lipid response to dietary intervention. Atherosclerosis 1995;118:S11-S27.
3. Ordovas JM, Schaefer EJ. Genes, variation of cholesterol and fat intake and serum lipids. Curr Opin Lipidol 1999;10:15-22.
4. Clifton PM, Abbey M. Genetic control of response to dietary fat and cholesterol. World Rev Nutr Diet 1997;80:1-14.
5. Weggemans RM, Zock PL, Urgert R, Katan MB. Differences between men and women in response of serum cholesterol to dietary changes. Eur J Clin Invest 1999;29:827-34.
6. Civeira F, Pocovi M, Cenarro A, Garces C, Ordovas JM. Adenine for guanine substitution -78 base pairs 5′ to the apolipoprotein (APO) A-I gene: Relation with high density lipoprotein cholesterol and APO A-I concentrations. Clin Genet 1993;44:307-12.
7. Barre DE, Guerra R, Verstraete R, Wang Z, Grundy SM, Cohen JC. Genetic analysis of a polymorphism in the human apolipoprotein A-I gene promoter: Effect on plasma HDL-cholesterol levels. J Lipid Res 1994;35:1292-6.
8. Tenkanen H, Lukka M, Jauhiainen M, Metso J, Baumann M, Peltonen L et al. The mutation causing the common apolipoprotein A-IV polymorphism is a glutamine to histidine substitution of amino acid 360. Arterioscler Thromb 1991;11:851-6.
9. Hixson JE, Powers PK. Restriction isotyping of human apolipoprotein A-IV. Rapid typing of known isoforms and detection of a new isoform that deletes a conserved repeat. J Lipid Res 1991;32:1529-35.
10. Boerwinkle E, Lee SS, Butler R, Schumaker VN, Chan L. Rapid typing of apolipoprotein B DNA polymorphisms by DNA amplification. Association between Ag epitopes of human apolipoprotein B-100, a signal peptide insertion/deletion polymorphism, and a 3′flanking DNA variable number of tandem repeats polymorphism of the apolipoprotein B gene. Atherosclerosis 1990;81:225-32.
11. Hixson JE, Vernier DT, Powers PK. Detection of SstI restriction site polymorphism in human APOC3 by the polymerase chain reaction. Nucl Acids Res 1991;19:196.
12. Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 1990;31:545-8.
13. Rust S, Funke H, Assmann G. Mutagenically separated PCR (MS-PCR): A highly specific one step procedure for easy mutation detection. Nucl Acids Res 1993;21:3623-9.
14. Kuivenhoven JA, de Knijff P, Boer JM, Smalheer HA, Botma GJ, Seidell JC et al. Heterogeneity at the CETP gene locus. Influence on plasma CETP concentrations and HDL cholesterol levels. Arterioscler Thromb Vasc Biol 1997;17:560-8.
15. Baier LJ, Sacchettini JC, Knowler WC, Eads J, Paolisso G, Tataranni PA et al. An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance. J Clin Invest 1995;95:1281-7.
16. Stocks J, Thorn JA, Galton DJ. Lipoprotein lipase genotypes for a common premature termination codon mutation detected by PCR-mediated site-directed mutagenesis and restriction digestion. J Lipid Res 1992;33:853-7.
17. Karpe F, Lundahl B, Ehrenborg E, Eriksson P, Hamsten A. A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels. Arterioscler Thromb Vasc Biol 1998;18:756-61.
18. Weggemans RM, Zock PL, Ordovas JM, Pedro-Botet J, Katan MB. Apoprotein E genotype and the response of serum cholesterol to dietary fat, cholesterol and cafestol. Atherosclerosis 2001;154:547-55.
19. SAS Institute Inc. SAS/STAT User's Guide, Version 6 4. Cary, NC: SAS Institute Inc.; 1989.
20. Weggemans RM, Zock PL, Meyboom S, Funke H, Katan MB. The apoproteinA4-1/2 polymorphism and the response of serum cholesterol to dietary cholesterol. J Lipid Res 2000;41:1623-8.
21. Jansen S, Lopez-Miranda J, Ordovas JM, Zambrana JL, Marin C, Ostos MA et al. Effect of 360His mutation in apolipoprotein A-IV on plasma HDL-cholesterol response to dietary fat. J Lipid Res 1997;38:1995-2002.
22. Mata P, Ordovas JM, Lopez-Miranda J, Lichtenstein AH, Clevidence B, Judd JT et al. ApoA-IV phenotype affects diet-induced plasma LDL cholesterol lowering. Arterioscler Thromb 1994;14:884-91.
23. Schaefer EJ, Lamon-Fava S, Ausman LM, Ordovas JM, Clevidence BA, Judd JT et al. Individual variability in lipoprotein cholesterol response to National Cholesterol Education Program Step 2 diets. Am J Clin Nutr 1997;65:823-30.
24. McCombs RJ, Marcadis DE, Ellis J, Weinberg RB. Attenuated hypercholesterolemic response to a high-cholesterol diet in subjects heterozygous for the apolipoprotein A-IV-2 allele. N Engl J Med 1994;331:706-10.
25. Wallace AJ, Mann JI, Sutherland WHF, Williams S, Chisholm A, Skeaff CM et al. Variants in the cholesterol ester transfer protein and lipoprotein lipase genes are predictors of plasma cholesterol response to dietary change. Atherosclerosis 2000;152:327-36.
26. Carmena-Ramon R, Ascaso JF, Real JT, Ordovas JM, Carmena R. Genetic variation at the ApoA-IV gene locus and response to diet in familial hypercholesterolemia. Arterioscler Thromb Vasc Biol 1998;18:1266-74.
27. Weinberg RB, Jordan MK, Steinmetz A. Distinctive structure and function of human apolipoprotein variant ApoA-IV-2. J Biol Chem 1990;265:18372-8.
28. Wallace AJ, Humphries SE, Fisher RM, Mann JI, Chisholm A, Sutherland WHF. Genetic factors associated with response of LDL subfractions to change in the nature of dietary fat. Atherosclerosis 2000;149:387-94.
29. Dullaart RP, Hoogenberg K, Riemens SC, Groener JE, van Tol A, Sluiter WJ et al. Cholesteryl ester transfer protein gene polymorphism is a determinant of HDL cholesterol and of the lipoprotein response to a lipid-lowering diet in type 1 diabetes. Diabetes 1997;46:2082-7.
30. Freeman DJ, Griffin BA, Holmes AP, Lindsay GM, Gaffney D, Packard CJ et al. Regulation of plasma HDL cholesterol and subfraction distribution by genetic and environmental factors. Associations between the TaqI B RFLP in the CETP gene and smoking and obesity. Arterioscler Thromb 1994;14:336-44.
31. Ordovas JM, Cupples LA, Corella D, Otvos JD, Osgood D, Martinez A et al. Association of cholesteryl eater transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk - The Framingham study. Arterioscler Thromb Vasc Biol 2000;20:1323-9.
32. Dachet C, Poirier O, Cambien F, Chapman J, Rouis M. New functional promoter polymorphism, CETP/-629, in cholesteryl eater transfer protein (CETP) gene related to CETP mass and high density lipoprotein cholesterol levels - Role of Sp1/Sp3 in transcriptional regulation. Arterioscler Thromb Vasc Biol 2000;20:507-15.
33. Gylling H, Kontula K, Koivisto UM, Miettinen HE, Miettinen TA. Polymorphisms of the genes encoding apoproteins A-I, B, C-III, and E and LDL receptor, and cholesterol and LDL metabolism during increased cholesterol intake. Common alleles of the apoprotein E gene show the greatest regulatory impact. Arterioscler Thromb Vasc Biol 1997;17:38-44.
34. Carmena-Ramon RF, Ordovas JM, Ascaso JF, Real J, Priego MA, Carmena R. Influence of genetic variation at the apo A-I gene locus on lipid levels and response to diet in familial hypercholesterolemia. Atherosclerosis 1998;139:107-13.
35. Lopez-Miranda J, Ordovas JM, Espino A, Marin C, Salas J, Lopez-Segura F et al. Influence of mutation in human apolipoprotein A-1 gene promoter on plasma LDL cholesterol response to dietary fat. Lancet 1994;343:1246-9.
36. Mata P, Lopez-Miranda J, Pocovi M, Alonzo R, Lahoz C, Marin C et al. Human apolipoprotein A-I gene promoter mutation influences plasma low density lipoprotein cholesterol response to dietary fat saturation. Atherosclerosis 1998;137:367-76.
37. Jansen S, Lopez-Miranda J, Salas J, Ordovas JM, Castro P, Marin C et al. Effect of 347-serine mutation in apoprotein A-IV on plasma LDL cholesterol response to dietary fat. Arterioscler Thromb Vasc Biol 1997;17:1532-8.
38. Rantala M, Rantala TT, Savolainen MJ, Friedlander Y, Kesaniemi YA. Apolipoprotein B gene polymorphisms and serum lipids: Meta-analysis of the role of genetic variation in responsiveness to diet. Am J Clin Nutr 2000;71:713-24.
39. Lopez-Miranda J, Jansen S, Ordovas JM, Salas J, Marin C, Castro P et al. Influence of the SstI polymorphism at the apolipoprotein C-III gene locus on the plasma low-density-lipoprotein-cholesterol response to dietary monounsaturated fat. Am J Clin Nutr 1997;66:97-103.