Influence of the ssti polymorphism at the apolipoprotein C-III gene locus on the plasma low-density-lipoprotein-cholesterol response to dietary monounsaturated fat

American Journal of Clinical Nutrition

Volumn 66, Issue 1, 1997, Pages 97-103

  López Miranda, José ^b   Jansen, Sergio ^b   Ordovas, José M ^b   Salas, Joaquin ^b   Marín, Carmen ^b   Castro, Pedro ^b   Ostos, Maria A ^b   Cruz, Gracia ^b   López Segura, Fernando ^b   Blanco, Angeles ^b   Jiménez Perepérez, José ^b   Pérez Jiménez, Francisco ^a  

^a HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^b NONE

Author keywords

APOC3; Apolipoprotein C III; DNA amplification; Genetic polymorphism; Genotyping; Low density lipoproteins; Low fat diets; Monounsaturated fatty acid rich diets; Polymerase chain reaction; S1 allele; S2 allele; SstI

Indexed keywords

APOLIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MONOUNSATURATED FATTY ACID;

ADULT; ALLELE; ARTICLE; CHOLESTEROL BLOOD LEVEL; FAT INTAKE; GENE LOCUS; GENE MUTATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN EXPERIMENT; LIPOPROTEIN BLOOD LEVEL; MALE; NORMAL HUMAN; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 1842289176     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/66.1.97     Document Type: Article

References (56)

1. The Adult Treatment Panel. Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adults Treatment Panel II). JAMA 1993;269:3015-23.
2. Jacobs DR, Anderson JT, Hannan P, Keys A, Blackburn H. Variability in individual serum cholesterol response to change in diet. Arteriosclerosis 1983;3:349-56.
3. Clarkson TB, McMahan MR. Individual differences in the response of serum cholesterol to change in diet: animal studies. In: Lauer RM, Skekelle RB, eds. Childhood prevention of atherosclerosis and hypertension. New York: Raven Press, 1980:127-35.
4. Brewer HB, Shulman R, Herbert P, Ronan R, Wehrly K. The complete amino acid sequence of alanine apolipoprotein (apo C-III), an apolipoprotein from human plasma very low density lipoprotein. J Biol Chem 1974;249:4975-84.
5. Sharpe CR, Sidoli A, Shelley CS, Lucero MA, Shoulders CC, Baralle FE. Human apolipoproteins A-I, A-II, C-II and C-III, cDNA sequences and mRNA abundances. Nucleic Acids Res 1984;12:3917-32.
6. Protter AA, Levy-Wilson B, Miller J, Bencen G, White T, Seilhamer JJ. Isolation and sequence analysis of the human apolipoprotein C-III gene and the intergenic region between the apo A-I and apo C-III genes. DNA 1984;3:449-56.
7. Karathanasis SK, Zannis VI, Breslow JL. Isolation and characterization of cDNA clones corresponding to two different human apo C-III alleles. J Lipid Res 1985;26:451-6.
8. Herbert P, Assmann G, Gotto AM, Fredrickson DS. Familial lipoprotein deficiency: abetalipoproteinemia, hypobetalipoproteinemia and Tangier disease. In: Stanbury JB, Wyngaarden JB, Fredrikson DS, Goldstein JL, Brown MS, eds. The metabolic basis of inherited disease. 5th ed. New York: McGraw-Hill Inc, 1982:589-651.
9. Brown VW, Baginsky ML. Inhibition of lipoprotein lipase by an apoprotein of human very low density lipoprotein. Biochem Biophys Res Commun 1972;46:375-82.
10. Krauss RM, Herbert PM, Levy RI, Fredrickson DS. Further observations on the activation and inhibition of lipoprotein lipase by apolipoproteins. Cir Res 1973;33:403-11.
11. McConathy WJ, Gesquiere JC, Bass H, Tartar A, Fruchart JC, Wang CS. Inhibition of lipoprotein lipase activity by synthetic peptides of apolipoprotein C-III. J Lipid Res 1992;33:995-1003.
12. Kinnunen PKJ, Ehnholm C. Effect of serum and C apoproteins from very low density lipoproteins on human postheparin plasma hepatic lipase. FEBS Lett 1976;65:354-7.
13. Shelburne F, Hanks J, Myers W, Quarfordt S. Effect of apoproteins on hepatic uptake of triglyceride emulsion in the rat. J Clin Invest 1980;65:652-8.
14. Windler E, Chao Y, Havel RJ. Regulation of the hepatic uptake of triglyceride rich lipoproteins in the rat: opposing effect of homologous apolipoprotein E and individual C apoproteins. J Biol Chem 1980;255:8303-7.
15. Windler E, Havel RJ, Inhibitory effects of C apolipoproteins from rats and humans on the uptake of triglyceride rich lipoproteins and their remnants by the perfused rat liver. J Lipid Res 1985;26:556-65.
16. Karathanasis SK. Apolipoprotein multigene family: tandem organization of human apolipoprotein AI, CIII and AIV genes. Proc Natl Acad Sci U S A 1985;82:6374-8.
17. Rees A, Shoulders CC, Stocks J, Galton DJ, Baralle FE. DNA polymorphism adjacent to the human apolipoprotein AI gene relationship to hypertriglyceridemia. Lancet 1983;1:444-6.
18. Rees A, Stocks J, Sharpe CR, et al. Deoxyribonucleic acid polymorphism in the apolipoprotein A-I-CIII gene cluster: association with hypertriglyceridemia. J Clin Invest 1985;76:1090-5.
19. Kessling AM, Berg K, Mockleby E, Humphries SE. DNA polymorphisms around the apo A-I gene in normal and hyperlipidaemic individuals selected for a twin study. Clin Genet 1986;29:285-90.
20. Paulweber BW, Friedl W, Krempler F, Humphries SE, Sandhofer F. Genetic variation in the apolipoprotein A-I-C-III-A-IV gene cluster and coronary heart disease. Atherosclerosis 1988;73:125-33.
21. Sinan T. Strong association of a single nucleotide substitution in the 3′-untranslated region of the apolipoprotein-CIII gene with common hypertriglyceridemia in Arabs. Clin Chem 1989;35:256-9.
22. Ordovas JM, Civeira F, Genest J, et al. Restriction fragment length polymorphisms of the apolipoprotein A-I, C-III, A-IV gene locus: relationships with lipids, apolipoproteins, and premature coronary artery disease. Atherosclerosis 1991;87:75-86.
23. Aalto-Setala K, Viikari J, Akerblom HK, Kuusela V, Kontula K. DNA polymorphisms of the apolipoprotein B and A-I/C-III genes are associated with variations of serum low density lipoprotein cholesterol level in childhood. J Lipid Res 1991;32:1477-87.
24. Shoulders CC, Harry PJ, Lagrost L, et al. Variation at the apo A-I/C-III/A-IV gene complex is associated with elevated plasma levels of apo CIII. Atherosclerosis 1991;87:239-47.
25. Sidoli A, Guidici G, Soria M, Vergani C. Restriction-fragment-lengthpolymorphisms in the AI-CIII gene complex occurring in a family with hypoalphalipoproteinemia. Atherosclerosis 1985;62:81-7.
26. Rees A, Stocks J, Paul H, Ochuchi Y, Galton D. Haplotypes identified by DNA polymorphisms at the apolipoprotein A-I and C-III loci and hypertriglyceridemia: a study in the Japanese population. Hum Genet 1986;72:168-71.
27. Lopez-Miranda J, Ordovas JM, Espino A, et al. Influence of mutation in human apolipoprotein A-I gene promoter on plasma LDL cholesterol response to dietary fat. Lancet 1994;343:1246-9.
28. Human Nutrition Information Service, Department of Agriculture. Composition of foods. Agriculture handbook no. 8. Washington, DC: US Government Printing Office, 1987.
29. Varela G. Tablas de Composición de Alimentos. (Food composition tables.) Madrid: Instituto de Nutricion CSIC, 1980 (in Spanish).
30. Terpstra AH, Woodward CJ, Sanchez-Muniz FJ. Improved techniques for the separation of serum lipoproteins by density gradient ultracentrifugation: visualization by prestaining and rapid separation of serum lipoproteins from small volumes of serum. Anal Biochem 1981; 111:149-57.
31. Bucolo G, David H. Quantitative determination of serum triglycerides by use of enzymes. Clin Chem 1973;19:476-82.
32. Allain CC, Poon LS, Chang CSG, Richmond W, Fu PC. Enzymatic determination of total serum cholesterol. Clin Chem 1974;20:470-5.
33. Riepponen P, Marniemi J, Rautaoja T. Immunoturbidimetric determination of apolipoprotein A-I and B in serum. Scand J Clin Lab Invest 1987;47:739-44.
34. Rose HB, Oklander M. Improved procedure for the extraction of lipid from human erythrocytes. J Lipid Res 1965;6:428-31.
35. Hixson JE, Powers PK. Restriction isotyping of human apolipoprotein A-IV: rapid typing of known isoforms and detection of a new isoform that deletes a conserved repeat. J Lipid Res 1991;32:1529-35.
36. Kontula K, Aalto-Setälä K, Kuusi T. Hämäläinen L, Syvänen AC. Apolipoprotein E polymorphism determined by restriction enzyme analysis of DNA amplified by polymerase chain reaction: a convenient alternative to phenotyping by isoelectric focusing. Clin Chem 1990;36:2087-92.
37. Ordovas JM, Lopez-Miranda J, Mata P, Perez-Jimenez F, Lichtenstein AH, Schaefer EJ. Gene-diet interaction in determining plasma lipid response to dietary intervention. Atherosclerosis 1995;118(suppl): S11-27.
38. Fisher EA, Blum CB, Zannis VI, Breslow JL. Independent effects of dietary saturated fat and cholesterol on plasma lipids, lipoproteins, and apolipoprotein E. J Lipid Res 1983;24:1039-48.
39. Tikkanen MJ, Huttunen JK, Enholm C, Pietinen P. Apolipoprotein E4 homozygosity predisposes to serum cholesterol elevation during high-fat diet. Arteriosclerosis 1990;10:285-8.
40. Savolainen MJ, Rantala M, Kervinen K, et al. Magnitude of dietary effects on plasma cholesterol concentration: role of sex and apolipoprotein E phenotype. Atherosclerosis 1991;86:145-52.
41. Manttari M, Kosninen P, Enholm C, Huttunen JK, Manninen V. Apolipoprotein E polymorphism influences the serum cholesterol response to dietary intervention. Metabolism 1991;40:217-21.
42. Cobb MM, Teitlebaum H, Risch N, Jekel J, Ostfeld A. Influence of dietary fat, apolipoprotein E phenotype, and sex on plasma lipoprotein levels. Circulation 1992;86:849-57.
43. Lopez-Miranda J, Ordovas JM, Mata P, et al. Effect of apolipoprotein E phenotype on diet-induced lowering of plasma low density lipoprotein cholesterol. J Lipid Res 1994;35:1965-75.
44. Tikkanen MJ, Xu CF, Hamalainen, et al. XbaI polymorphism of the apolipoprotein B gene influences plasma lipid response to diet intervention. Clin Genet 1990;37:327-34.
45. Mata P, Ordovas JM, Lopez-Miranda J, et al. ApoA-IV phenotype affects diet-induced plasma LDL cholesterol lowering. Arterioscler Thromb 1994;14:884-91.
46. McCombs RJ, Marcadis DE, Ellis J, Weinberg RB. Attenuated hypercholesterolemic response to a high-cholesterol diet in subjects heterozygous for the apolipoprotein A-IV-2 allele. N Engl J Med 1994;331:706-10.
47. Keys A, Anderson JT, Grande F. Prediction of serum cholesterol responses of man to changes in fats in the diet. Lancet 1957;2:959-66.
48. Hegsted DM, McGandy RB, Myers ML, Stare FJ. Quantitative effects of dietary fat on serum cholesterol in man. Am J Clin Nutr 1965;17:281-95.
49. Mensink RP, Katan MB. Effect of dietary fatty acids on serum lipids and lipoproteins. Arterioscler Thromb 1992;12:911-9.
50. Von Eckardstein A, Funke H, Schulte M, Erren M, Schulte H, Assmann G. Nonsynonymous polymorphic sites in the apolipoprotein (apo) A-IV gene are associated with changes in the concentration of apo B- and apoA-I containing lipoproteins in a normal population. Am J Hum.Genet 1992;50:1115-28.
51. Antonarakis SE, Oettgen P, Chakravarti A, et al. DNA polymorphism haplotypes of the human apolipoprotein APOA1-APOC3-APOA4 gene cluster. Hum Genet 1988;80:265-73.
52. Paul-Hayase H, Rosseneu M, Robinson D, Van Bervliet JP, Deslypere JP, Humphries SE. Polymorphisms in the apolipoprotein (apo) AI-CIII-AIV gene cluster: detection of genetic variation determining plasma apo AI, apo CIII and apo AIV concentrations. Hum Genet 1992;88:439-46.
53. Dammerman M, Sandkiujl LA, Halaas JL, Chung W, Breslow JL. An apolipoprotein CIII haplotype protective against hypertriglyceridemia is specified by promoter and 3′ untranslated region polymorphisms. Proc Natl Acad Sci U S A 1993;90:4562-6.
54. Li WW, Leff T. Regulation of apolipoprotein CIII gene transcription by insulin: characterization of an insulin response element in the CIII promoter. Circulation 1994;90:I-401 (abstr).
55. Li WW, Dammerman MM, Smith JD, et al. A common variant of the apo Cm promoter associated with hypertriglyceridemia is defective in its transcriptional response to insulin. Circulation 1994;90:I-401 (abstr).
56. Ramarkrishnan R, Talmud P, Humphries S, et al. Relationship of apoprotein B and apoprotein C-III polymorphism with postprandial lipemia. Circulation 1995;92:I493 (abstr).