Microwave assay for detecting protein conformation in solution

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 4574, Issue , 2001, Pages 137-143

  Taylor, Kimberly ^a   Van der Weide, Daniel ^a  

^a University of Wisconsin Madison   (United States)

Author keywords

Dielectric spectroscopy; Microwave spectroscopy; Optical spectroscopy; Protein conformation; Protein thermodynamics; Ribonuclease a; Slot antenna

Indexed keywords

DIELECTRIC PROPERTIES; MICROWAVE SPECTROSCOPY; PROTEINS; SLOT ANTENNAS; ULTRAVIOLET SPECTROSCOPY;

DIELECTRIC SPECTROSCOPY;

MICROWAVE DEVICES;

EID: 0035768262     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (11)

1. Creighton, T.E. Proteins: Structures and molecular properties. New York: W.H. Freeman and Company, 1993.
2. Pethig, R. Dielectric and electronic properties of biological materials. Chichester: John Wiley & Sons, 1979.
3. Pethig, R. (1992) "Protein-water interactions determined by dielectric methods." Annu. Rev. Phys. Chem. 43, 177-205.
4. Feldman, Y., Andrianov, A., Polygalov, E., Ermolina, I., Romanychev, G., Zuev, Y. and Milgotin, B. (1996) "Time domain dielectric spectroscopy: An advanced measuring system." Rev. Sci. Instrum. 67, 3208-3216.
5. Facer, G.R., Notterman, D.A. and Sohn, L.L. (2001) "Dielectric spectroscopy for bioanalysis: From 40 hz to 26.5 ghz in a microfabricated wave guide." Applied Physics Letters 78,996-998.
6. Xu, Y., Bosisio, R.G., Bonincontro, A., Pedone, F. and Mariutti, G.F. (1993) "On the measurement of microwave permittivity of biological samples using needle-type coaxial probes." IEEE Trans. Instrum. Meas. 42, 822-827.
7. Wichaldit, C., Peck, J.R., Lin, Z., Hamers, R.J., Hagness, S.C. and van der Weide, D.W. (2001) "Resonant slot antennas as transducers of DNA hybridization: A computational feasibility study." IEEE MTT-S Int. Microwave Symp. Dig. 1,163-166.
8. Klink, T.A., Woycechowsky, K.J., Taylor, K.M. and Raines, R.T. (2000) "Contribution of disulfide bonds to the conformational stability and catalytic activity of ribonuclease a." European Journal of Biochemistry 267, 566-572.
9. Pace, C.N., Grimsley, G.R., Thomas, S.T. and Makhatadze, G.I. (1999) "Heat capacity change for ribonuclease a folding." Protein Science 8, 1500-1504.
10. Gill, S.C. and von Hippel, P.H. (1989) "Calculation of protein extinction coefficients from amino acid sequence data." Anal. Biochem. 182, 319-326.
11. Bohr, H. and Bohr, J. (2000) "Microwave-enhanced folding and denaturation of globular proteins." Phys. Rev. E61, 4310-4314.