G649, an allelic variant of the human H2 receptor with low basal activity, is resistant to upregulation upon antagonist exposure

Pharmacogenomics Journal

Volumn 1, Issue 1, 2001, Pages 78-83

  Fukushima, Y ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Allelic variant; cAMP; CHO cells; Desensitizatlon; Histamine H2 receptor; Upregulatlon

Indexed keywords

CIMETIDINE; CYCLIC AMP; DRUG DERIVATIVE; HISTAMINE; HISTAMINE H2 RECEPTOR; HISTAMINE H2 RECEPTOR ANTAGONIST; TIOTIDINE;

ALLELE; ANIMAL; ARTICLE; BIOSYNTHESIS; CHO CELL; DRUG EFFECT; GENETICS; HAMSTER; HUMAN; METABOLISM; MUTATION; PHYSIOLOGY; UPREGULATION;

ALLELES; ANIMALS; CHO CELLS; CIMETIDINE; CRICETINAE; CYCLIC AMP; HISTAMINE; HISTAMINE H2 ANTAGONISTS; HUMANS; MUTATION; RECEPTORS, HISTAMINE H2; UP-REGULATION;

EID: 0035756960     PISSN: 1470269X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.tpj.6500011     Document Type: Article

References (4)

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