Efficacy of itraconazole as a combined continuous/pulse therapy in feline dermatophytosis: Preliminary results in nine cases

Veterinary Dermatology

Volumn 12, Issue 6, 2001, Pages 347-350

  Colombo, S ^a,c   Cornegliani, L ^b   Vercelli, A ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b Ambulatorio Veterinario Associato   (Italy)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Cat; Dermatophytosis; Itraconazole; Pulse therapy

Indexed keywords

CANIS; FELIDAE; FELIS CATUS; MICROSPORUM CANIS;

ANTIFUNGAL AGENT; ITRACONAZOLE;

ANIMAL; ANIMAL DISEASE; ARTICLE; CAT; CAT DISEASE; DERMATOMYCOSIS; DRUG ADMINISTRATION; DRUG PULSE THERAPY; EVALUATION; FEMALE; ISOLATION AND PURIFICATION; MALE; MICROSPORUM; ORAL DRUG ADMINISTRATION; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ANIMALS; ANTIFUNGAL AGENTS; CAT DISEASES; CATS; DERMATOMYCOSES; DRUG ADMINISTRATION SCHEDULE; FEMALE; ITRACONAZOLE; MALE; MICROSPORUM; PULSE THERAPY, DRUG; TREATMENT OUTCOME;

EID: 0035752093     PISSN: 09594493     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0959-4493.2001.00274.x     Document Type: Article

References (16)

1. Scott, D.W., Miller, W.H., Griffin, C.E. Muller and Kirk's Small Animal Dermatology, 6th edn. Philadelphia: W.B. Saunders, 2001: 336.
2. Moriello, K.A., DeBoer, D.J. Feline dermatophytosis. Recent advances and recommendations for therapy. In: Kunkle G. Feline dermatology. Veterinary Clinics of North America: Small Animal Practice 1995; 25: 901-21.
3. Moriello, K.A., DeBoer, D.J. Efficacy of griseofulvin and itraconazole in the treatment of experimentally induced dermatophytosis in cats. Journal of the American Veterinary Medical Association 1995; 207: 439-44.
4. Hill, P.B., Moriello, K.A., Shaw, S.E. A review of systemic antifungal agents. Veterinary Dermatology 1995; 6: 59-66.
5. Martin, S. Itraconazole. Compendium on Continuing Education for the Practicing Veterinarian 1999; 2: 145-7.
6. Cauwenbergh, G., Degreef, H., Heykants, J. et al. Pharmacokinetic profile of orally administered itraconazole in human skin. Journal of the American Academy of Dermatology 1988; 18: 263-8.
7. De Doncker, P., Decroix, J., Pierard, G.E. et al. Antifungal pulse therapy for onychomycosis. A pharmacokinetic and pharmacodynamic investigation of monthly cycles of 1-week pulse therapy with itraconazole. Archives of Dermatology 1996; 132: 34-41.
8. De Doncker, P., Gupta, A., Marynissen, G. et al. Itraconazole pulse therapy for onychomycosis and dermatomycoses: an overview. Journal of the American Academy of Dermatology 1997; 37: 969-74.
9. Gupta, A.K., Hofstader, S.L.R., Summerbell, R.C. et al. Treatment of tinea capitis with itraconazole capsule pulse therapy. Journal of the American Academy of Dermatology 1998; 39: 216-19.
10. Havu, V., Brandt, H., Heikkila, H. et al. Continuous and intermittent itraconazole dosing schedules for the treatment of onychomycosis: a pharmacokinetic comparison. British Journal of Dermatology 1999; 140: 96-101.
11. DeBoer, D.J., Moriello, K.A. Inability of two topical treatments to influence the course of experimentally induced dermatophytosis in cats. Journal of the American Veterinary Medical Association 1995; 207: 52-7.
12. Sparkes, A.H., Gruffydd-Jones, T.J., Stokes, C.R. Acquired immunity in experimental feline Microsporum canis infection. Research in Veterinary Science 1996; 61: 165-8.
13. DeBoer, D.J., Moriello, K.A. Development of an experimental model of Microsporum canis infection in cats. Veterinary Microbiology 1994; 42: 289-95.
14. Boothe, D.M., Herring, I., Calvin, J. et al. Itraconazole disposition after single oral and intravenous and multiple oral dosing in healthy cats. American Journal of Veterinary Research 1997; 58: 872-7.
15. Sparkes, A.H., Werrett, G., Stokes, C.R. et al. Microsporum canis. inapparent carriage by cats and the viability of arthrospores. Journal of Small Animal Practice 1994; 35: 397-401.
16. Paterson, S. Miconazole/clorhexidine shampoo as an adjunct to systemic therapy in controlling dermatophytosis in cats. Journal of Small Animal Practice 1999; 40: 163-6.