Peptide analog of fibronectin that inhibits cell migration and ERK 1/2 activity

Peptides

Volumn 22, Issue 12, 2001, Pages 1949-1953

  Szaniawska, B ^a   Trembacz, H ^a   Miloszewska, J ^a   Lipkowski, A W ^b   Misicka, A ^b   Ostrowski, J ^c   Janik, P ^a  

^a INSTITUTE OF ONCOLOGY   (Poland)

^b MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^c Department of Gastroenterology Medical Center for Postgraduate Education ^*  (Poland)

Author keywords

Erk; Fak; Fibronectin; Migration

Indexed keywords

FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OLIGOPEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; CELL ADHESION; CELL CULTURE; CELL MOTION; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; HUMAN; MOLECULAR GENETICS; OVARY TUMOR; PATHOLOGY; PHOSPHORYLATION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; BLOTTING, WESTERN; CELL ADHESION; CELL MOVEMENT; FEMALE; FIBRONECTINS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; OVARIAN NEOPLASMS; PHOSPHORYLATION; TUMOR CELLS, CULTURED;

EID: 0035748723     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(01)00547-2     Document Type: Article

References (23)

1. A. Albini Y. Iwamoto H.K. Kleinman G.R. Martin S.S. Aaronson J.M. Kozlowski R.N. McEwan A rapid in vitro assay for quantitating the invasive potential of tumor cells Cancer Res 47 1987 3239 3245
2. A.R. Asthagiri C.M. Nelson A.F. Horwitz D.A. Lauffenburger Quantitative relationship among integrin-ligand binding, adhesion, and signaling via focal adhesion kinase and extracellular signal-regulated kinase 2 J Biol Chem 274 1999 27119 27127
3. FAK, paxillin, and talin J Cell Biol 147 1999 619 629
4. Q. Chen M.S. Kinch T.H. Lin K. Burridge R.L. Juliano Integrin-mediated cell adhesion activates mitogen- activated protein kinases J Biol Chem 269 1994 26602 26605
5. F.S. David P.E. Zage E.E. Marcantonio Integrins interact with focal adhesions through multiple distinct pathways J Cell Physiol 181 1999 74 82
6. S.L. Drake J. Varnum K.H. Mayo P.C. Letourneau L.T. Furcht J.B. McCarthy Structural features of fibronectin synthetic peptide FN-C/H II, responsible for cell adhesion, neurite extension, and heparan sulfate binding J Biol Chem 268 1993 15859 15867
7. J. Gu M. Tamura R. Pankov E.H.J. Danen T. Takino K. Matsumoto K.M. Yamada Shc and FAK differentially regulate cell motility and directionality modulated by PTEN J Cell Biol 146 1999 389 403
8. J.L. Guan Role of focal adhesion kinase in integrin signaling Int J of Biochem & Cell Biol 29 1997 1085 1096
9. J. Heino Biology of tumor cell invasion interplay of cell adhesion and matrix degardation Int J Cancer 65 1996 717 722
10. M. Hu R.E. Pollock G.L. Nicolson Purification and characterization of human lung fibroblast motility-stimulating factor for human soft tissue sarcoma cells identification as an NH2-terminal fragment of human fibronectin Cancer Res 57 1997 3577 3584
11. D. Ilić C.H. Damsky T. Yamamoto Focal adhesion kinase at the crossroads of signal transduction J Cell Sci 110 1997 401 407
12. M. LeGall D. Grall J.C. Chambard J. Pouyseegeur E. Van Obberghen-Schilling An anchorage dependent signal distinct from p42/44 MAK kinase activation is required for cell cycle progression Oncogene 17 1998 1271 1277
13. C.H. Lowry M.R. Rosenbrough R.J. Randall Protein measurement with the Folin phenol reagent J Biol Chem 193 1951 265 275
14. J. Miłoszewska H. Trembacz P. Janik Signal transduction in confluent C3H 10T11/2 cells. The role of focal adhesion kinase Acta Biochim Pol 48 2001 175 181
15. G. Mugnai K. Lewandowska B. Carmnemolla L. Zardi L.A. Culp Modulation of matrix adhesive responses of human neuroblastoma cells by neighboring sequence in the fibronectin J Cell Biol 106 1988 931 943
16. J. Ostrowski M. Woszczyński P. Kowalczyk T. Wocial E. Henning L. Trzeciak P. Janik K. Bomsztyk Increased activity of MAP, p70S6 and p90rs kinases is associated with AP-1 activation in spontaneous liver tumours, but not in adjecent tissue in mice Br J Cancer 82 2000 1041 1050
17. L.C. Plantefaber R.O. Hynes Changes in integrin receptors on oncogenically transformed cells Cell 56 1989 281 290
18. M.W. Renshaw L.S. Price M.A. Schwartz Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase J Cell Biol 147 1999 611 618
19. L.A. Repesh A new in vitro assay for quantitating tumor cell invasion Invasion Metastasis 9 1989 192 208
20. A. Sharma J.A. Askari E.Y. Jones D.J. Stuart Crystal structure of a heparin and integrin-binding segment of human fibronectin EMBO J 18 1999 1468 1479
21. K. Skorstengaard M.S. Jensen T.E. Petersen S. Magnusson Purification and complete primary structures of the heparin-, cell- and DNA binding domains of bovine plasma fibronectin Eur J Biochem 154 1986 15 29
22. B. Szaniawska K. Gawrychowski P. Janik The effect of protein kinase C inhibitors on invasion of human ovary cancer cells Neoplasma 45 1998 7 11
23. B. van de Water J.F. Nagelkerke J.L. Stevens Dephosphorylation of focal adhesion kinase (FAK) and loss of focal contacts precede caspase-mediated cleavage of FAK during apoptosis in renal epithelial cells J Biol Chem 274 1999 13328 13337