Age-dependent consequences of seizures and the development of temporal lobe epilepsy in the rat

Developmental Neuroscience

Volumn 23, Issue 3, 2001, Pages 219-223

  Dubé, Céline ^a   Da Silva Fernandes, Maria José ^a,b   Nehlig, Astrid ^a  

^a INSERM   (France)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Brain development; Cerebral glucose; Epilepsy; Glucose metabolism; Rat; Temporal lobe

Indexed keywords

CARBON 14; DEOXYGLUCOSE; LITHIUM; PILOCARPINE; SELENIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BRAIN INJURY; BRAIN REGION; BRAIN STEM; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; EPILEPTOGENESIS; FEMALE; FOREBRAIN; GLUCOSE METABOLISM; MALE; METABOLIC RATE; NERVE CELL LESION; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE; TEMPORAL LOBE EPILEPSY;

EID: 0035743036     PISSN: 03785866     EISSN: None     Source Type: Journal    
DOI: 10.1159/000046147     Document Type: Conference Paper

References (26)

1. The pilocarpine model of epilepsy
2. Review: Cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: A novel experimental model of intractable epilepsy
3. The susceptibility of rats to pilocarpine-induced seizures is age-dependent
4. Spatial and temporal evolution of neuronal activation, stress and injury in lithium-pilocarpine seizures in adult rats
5. Developmental aspects of the pilocarpine model of epilepsy
6. Progressive metabolic changes underlying the chronic reorganization of brain circuits during the silent phase of the lithium-pilocarpine model of epilepsy in the immature and adult rat
7. Quantitative autoradiographic measurement of local cerebral glucose utilization in freely moving rats during postnatal development
8. A metabolic and neuropathological approach to the understanding of plastic changes that occur in the immature and adult rat brain during lithium-pilocarpine-induced epileptogenesis
9. Correlation between hypermetabolism and neuronal damage during status epilepticus induced by lithium-pilocarpine in immature and adult rats
10. Metabolic changes in cerebral cortex, hippocampus and cerebellum during sustained bicuculline-induced seizures
11. 14C-deoxyglucose study in the lithium-pilocarpine model in rat
12. 14C-deoxyglucose study
13. Metabolic alterations underlying the development of hypermetabolic necrosis in the substantia nigra in status epilepticus
14. Metabolic factors during prolonged seizures and their relation to nerve cell death
15. The reaction and adaptation of the central nervous system to stagnant hypoxia and anoxia during ontogeny
16. Glucose and ketone body utilization by the brain of neonatal rats
17. Maturation of kainic acid-induced seizure brain damage in the rat. Clinical, electroencephalographic and metabolic observations
18. Ontogenetic development of acetylcholine and atropine epileptogenic cortical foci in rats
19. Endogenous control of epilepsy: The nigral inhibitory system
20. The role of basal ganglia in the control of generalized absence seizures
21. Substantia nigra-mediated anticonvulsant actions: Role of nigral output pathways
22. Interictal metabolic anatomy of mesial temporal lobe epilepsy
23. Is interictal temporal hypometabolism related to mesial temporal sclerosis? A positron emission tomography/magnetic resonance imaging confrontation
24. Functional neuropathology of temporal lobe epilepsy
25. Status epilepticus results in reversible neuronal injury in infant rat hippocampus: Novel use of a marker
26. Pentylenetetrazol induces cell suffering but not death in the immature rat brain