Developmental aspects of the pilocarpine model of epilepsy

Epilepsy Research

Volumn 26, Issue 1, 1996, Pages 115-121

  Priel, Margareth Rose ^a   Dos Santos, Neide Ferreira ^a   Cavalheiro, Esper A ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

epilepsy; hippocampus; ontogenesis; rat; synaptic reorganization

Indexed keywords

METHYLSCOPOLAMINE; PILOCARPINE;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE PREDISPOSITION; EPILEPSY; HIPPOCAMPUS; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

AGE FACTORS; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; DISEASE MODELS, ANIMAL; EPILEPSY; MALE; PILOCARPINE; RATS; RATS, WISTAR; STATUS EPILEPTICUS;

EID: 0030551285     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(96)00047-2     Document Type: Conference Paper

References (32)

1. [1] Abercrombie, M., Estimation of nuclear population from microtome sections, Anat. Rec., 94 (1946) 239-247.
2. [2] Aicardi, J. and Chevrie, J.J., Consequences of status epilepticus in infants and children, Adv. Neurol., 34 (1983) 115-125.
3. [3] Babb, T.L., Kupfer, W.R., Pretorius, J.K., Crandall, P.H. and Levesque, M.F., Synaptic recurrent excitation of granule cells by mossy fibers in human epileptic hippocampus, Neuroscience, 42 (1991) 351-363.
4. [4] Cavalheiro, E.A., Leite, J.P., Bortolotto, Z.A., Turski, W.A., Ikonomidou, C. and Turski, L., Long-term effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures, Epilepsia, 32 (1991) 778-782.
5. [5] Cavalheiro, E.A., Silva, D.F., Turski, W.A., Calderazzo-Filho, L.S., Bortolotto, Z.A. and Turski, L., The susceptibility of rats to pilocarpine-induced seizures is age-dependent, Dev. Brain Res., 37 (1987) 43-58.
6. [6] Coyle, J.T. and Yamamura, H.I., Neurochemical aspects of the ontogenesis of cholinergic neurons in the rat brain, Brain Res., 118 (1976) 429-440.
7. [7] Cronin, J., Obenaus, A., Houser, C.R. and Dudek, F.E., Electrophysiology of dentate granule cells after kainate-induced synaptic reorganization of mossy fiber, Brain Res., 573 (1992) 305-310.
8. [8] De Sarro, G., Meldrum, B.S. and Reavill, C., Anticonvulsant action of 2-amino-7-phosphonoheptanoic acid in the substantia nigra, Eur. J. Pharmacol., 106 (1985) 175-179.
9. A-receptor subtypes during postnatal development: an immunohistochemical study, J. Neurosci., 14 (1994) 5302-5324.
10. [10] Gonzales, L.P. and Hettinger, M.K., Intranigral muscimol suppresses ethanol withdrawal seizures, Brain Res., 298 (1984) 163-166.
11. [11] Hauser, W.A. and Kurland, L.T., The epidemiology of epilepsy in Rochester, Minnesota, 1935-1967, Epilepsia, 16 (1975) 1-66.
12. [12] Insel, T.R., Miller, L.P. and Gelhard, R.E., The ontogeny of excitatory amino acid receptors in rat forebrain-I. N-methyl-D-aspartate and quisqualate receptors. Neuroscience, 35 (1990) 31-43.
13. [13] Leite, J.P., Bortolotto, Z.A. and Cavalheiro, E.A., Spontaneous recurrent seizures in rats: an experimental model of partial epilepsy. Neurosci. Biobeh. Rev., 14 (1990) 511-517.
14. [14] Lemos, T. and Cavalheiro, E.A., Suppression of pilocarpine-induced status epilepticus and the late development of epilepsy in rats, Exp. Brain Res., 102 (1995) 423-428.
15. [15] Mathern, G.W., Cifuentes, F., Leite, J.L., Pretorius, J.K. and Babb, T.L., Hippocampal EEG excitability and chronic spontaneous seizures are associated with aberrant synaptic reorganization in the rat intrahippocampal kainate model, Electroencephalogr. Clin. Neurophysiol., 87 (1993) 326-339.
16. [16] Matthews, D.A., Nadler, J.V., Lynch, G.S. and Cotman, C.W., Development of cholinergic innervation in the hippocampal formation of the rat, Dev. Biol., 36 (1974) 130-141.
17. [17] Mello, L.E.A.M., Cavalheiro, E.A., Tan, A.M., Kupfer, W.R., Pretorius, J.K., Babb, T.L. and Finch, D.M., Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: cell loss and mossy fiber sprouting, Epilepsia, 34 (1993) 985-995.
18. [18] Moshé, S.L., Seizures in the developing brain, Neurology, 43 (1993) S3-S7.
19. [19] Moshé S.L. and Albala, B.J., Nigral muscimol infusions facilitate the development of seizures in developing rats, Dev. Brain Res., 13 (1984) 305-308.
20. [20] Mouritzen-Dam, A., Hippocampal neuron loss in epilepsy and after experimental seizures, Acta Neurol. Scand., 66 (1982) 601-642.
21. [21] Phelps, P.E. and Adinolfi, A.M., The postnatal development of the substantia nigra: a light and electron microscopy study, J. Comp. Neurol., 209 (1982) 123-138.
22. 3H] propylbenzylcholine mustard, Brain Res. Rev., 1 (1979) 185-205.
23. [23] Sagar, H.J. and Oxbury, J.M., Hippocampal neuron loss in temporal lobe epilepsy: correlation with early childhood convulsions, Ann. Neurol., 22 (1987) 334-340.
24. [24] Sloviter, R.S., Permanently altered hippocampal structure, excitability and inhibition after status epilepticus in the rat: the 'dormant basket cell' hypotheses and its possible relevance to temporal lobe epilepsy, Hippocampus, 1 (1991) 41-66.
25. B receptors in seizures in rats pups, Dev. Brain Res., 47 (1989) 143-146.
26. [26] Sutula, T.P., Cascino, G., Cavazos, J., Parada, I., Ramirez, L., Mossy fiber synaptic reorganization in the epileptic human temporal lobe. Ann. Neurol., 26 (1989) 321-330.
27. [27] Swann, J.W., Brady, R.J. and Martin, D.L., Postnatal development of GABA-mediated synaptic inhibition in rat hippocampus, Neuroscience, 28 (1988) 551-562
28. [28] Tremblay, E., Roisin, M.P., Represa, A. Charriaut-Marlangue, C. and Ben-Ari, Y., Transient increased density of NMDA binding sites in the developing rat hippocampus, Brain Res., 461 (1988) 393-396.
29. [29] Turski, W.A., Cavalheiro, E.A., Schwarz, M., Czucwar, S.J., Kleinrok, Z. and Turski, L., Limbic seizures produced by pilocarpine in rats: behavioral, electroencephalographic and neuropathological study, Behav. Brain Res., 9 (1983) 315-335.
30. [30] Turski, L., Cavalheiro, E.A., Schwarz, M., Turski, W.A., Moraes Mello, L.E.A., Bortolotto, Z.A., Klockgether, T. and Sontag, K.H., Susceptibility of seizures produced by pilocarpine in rats after microinjection of isoniazid and γ-vinyl-GABA into the substantia nigra, Brain Res., 370 (1986) 294-309.
31. [31] Turski, L., Cavalheiro, E.A., Turski, W.A. and Meldrum, B.S., Excitatory neurotransmission within substantia nigra pars reticulata regulates threshold for seizures produced by pilocarpine in rats: effects of intranigral 2-amino-7-phosphonoheptanoate and N-methyl-D-aspartate, Neuroscience, 18 (1986) 61-77.
32. 1 pyramidal cells of hiperexcitable hippocampal slices from kainic acid-treated rats, Neuroscience, 52 (1993) 541-554.