Formation of novel bioactive metabolites from the reactions of pro-inflammatory oxidants with polyphenolics

BioFactors

Volumn 15, Issue 2-4, 2001, Pages 79-81

  Boersma, Brenda J ^a,b   Patel, Rakesh P ^a   Botting, Nigel ^a   Roger White, C ^a   Parks, Dale ^a   Barnes, Stephen ^a   Darley Usmar, Victor M ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; ARGININE; GENISTEIN; HALOGEN; HYPOCHLORITE; ISOFLAVONE DERIVATIVE; MYELOPEROXIDASE; NITROGEN; POLYPHENOL DERIVATIVE; REACTIVE OXYGEN METABOLITE;

ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CHEMICAL MODIFICATION; DRUG MECHANISM; DRUG METABOLISM; HALOGENATION; HUMAN; INFLAMMATION; OXIDATION; OXIDATIVE STRESS; PHARMACOPHORE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0035736545     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.5520150205     Document Type: Article

References (8)

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3. Enhances antioxidant activity after chlorination of quercetin by hypochlorous acid
4. Chlorination and nitration of soy isoflavones
5. Formation of nitrating and chlorinating species by reaction of nitrite with hypochlorous acid
6. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in LDL isolated from human atherosclerotic intima
7. Mechanisms of the pro- and anti-oxidant actions of nitric oxide in atherosclerosis
8. Cell signaling by reactive nitrogen and oxygen species in atherosclerosis