Synthesis and biological studies of a new ginkgolide C derivative: Evidence that the cardioprotective effect of ginkgolides is unrelated to PAF inhibition

Drug Development Research

Volumn 54, Issue 4, 2001, Pages 191-201

  Pietri, Sylvia ^a   Liebgott, Thibaut ^a   Finet, Jean Pierre ^a   Culcasi, Marcel ^a,b   Billottet, Ludovic ^a   Bernard Henriet, Christiane ^a  

^a CNRS   (France)

^b SARL OXYLAB   (France)

Author keywords

Cardioprotection; Ginkgolide

Indexed keywords

7 O (4 METHYLPHENYL)GINKGOLIDE C; BISMUTH DERIVATIVE; GINKGOLIDE B; GINKGOLIDE C; GINKGOLIDE DERIVATIVE; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; TRIS(4 METHYLPHENYL)BISMUTH DIACETATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SOLUBILITY; DRUG SYNTHESIS; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEMODYNAMICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; IN VITRO STUDY; ISOLATED HEART; MALE; NONHUMAN; RABBIT; RAT; REACTION ANALYSIS; REPERFUSION INJURY; THROMBOCYTE; THROMBOCYTE AGGREGATION INHIBITION;

EID: 0035726579     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.10029     Document Type: Article

References (2)

1. Amri H, Ogwuegbu SO, Boujrad N, Drieu K, Papadopoulos V. 1996. In vivo regulation of the peripheral-type benzodiazepine receptor and glucocorticoid synthesis by Ginkgo biloba extract (EGb 761) and isolated ginkgolides. Endocrinology 137:5707-5718.
2. Barton DHR, Finet, J-P, Pichon G. 1986. The catalytic effect of copper ions in the phenylation reaction of David and Thieffry. J Chem Soc Chem Commun 65-66.