Acute toxicity of three novel derivatives of pyridinium chloride to bacteria, human cell culture and rodents

Periodicum Biologorum

Volumn 103, Issue 4, 2001, Pages 347-350

  Lovrić, Jasna ^a   Krenajz Sirotković, Vlasta ^a   Burger, Nicoletta ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Acute toxicity; Bioassay; C 57 Black mice; Dehydrogenase activity; IC50; LD50; McCoy cells; Mono pyridinium compounds; Pseudomonas putida

Indexed keywords

1 BENZOYLETHYLPYRIDINIUM 4 ALDOXIME CHLORIDE; 1 BENZOYLETHYLPYRIDINIUM CHLORIDE; 1 PHENACYL 2 METHYLPYRIDINIUM CHLORIDE; PYRIDINIUM DERIVATIVE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GROWTH; BACTERIUM; BIOASSAY; CELL GROWTH; COLORIMETRY; CONCENTRATION RESPONSE; CYTOTOXICITY; DRUG MECHANISM; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IC 50; MALE; MOUSE; NONHUMAN; PSEUDOMONAS PUTIDA;

EID: 0035725575     PISSN: 00315362     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. The biochemical and cellular basis of cell proliferation assay that use tetrazolium salts
2. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability
3. Comparison of several microbiological toxicity screening tests
4. Pharmacological effects of oximes how relevant are they (Review)
5. The efficacy of monopyridinium (2-PAAM, 2-PAEM) and bispyridinium (obidoxime, HI-6) oximes against mevinphos in mice
6. Spectrophotometric studies of some novel derivatives of pyridinium chloride
7. A critical assessment of the use of microculture tetrazolium assays to measure cell growth and function. Review
8. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assay
9. Oecd Guideline for testing of chemicals
10. Treatment of carbamate and organophosphate intoxication with new oximes
11. Efficiency of imidazolium and quinuclidinium derivatives combined with HI-6 or diazeparn in soman and tabun poisoning
12. Binding sites on acetylcholinesterase and butyrylcholinesterase for pyridinium and imidazolium oximes, and other reversible ligands
13. Inhibition of acetylcholinerase by three new pyridinium compounds and their effect on phosphonylation of the enzyme
14. A rapid toxiity test using Pseudomonas fluoresces
15. Toxicity of dimethylsulfoxide as a solvent in bioassay system with HeLa cells evaluated colorimetrically with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide
16. Toxicity evaluation of the mycotoxins, citrinin and ochratoxin A, using several animal cell lines
17. Tetrazolium based assay for cellular viability: A critical examination of selected parameters effecting formazan production