Molecular cloning, expression and modelling of cat allergen, cystatin (Fel d 3), a cysteine protease inhibitor

Clinical and Experimental Allergy

Volumn 31, Issue 8, 2001, Pages 1279-1286

  Ichikawa, K ^a,b   Vailes, L D ^a   Pomes A ^a   Chapman, M D ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Bronchial asthma; Cat allergy; Cystatin; Cysteine protease inhibitor; IgE

Indexed keywords

ALLERGEN; CYSTATIN; CYSTEINE PROTEINASE INHIBITOR; IMMUNOGLOBULIN E; LIPOCALIN;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; ASTHMA; CAT; CHEMICAL STRUCTURE; CLINICAL ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; DANDER; DNA LIBRARY; DOG; ESCHERICHIA COLI; HUMAN; IMMUNOASSAY; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SERUM; SKIN;

ALLERGENS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATS; CATTLE; CLONING, MOLECULAR; CYSTATINS; CYSTEINE PROTEINASE INHIBITORS; DOGS; ESCHERICHIA COLI; GENE EXPRESSION; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0035724248     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.2001.01169.x     Document Type: Article

References (45)

1. Amino acid sequence of Fel d I, major allergen of the domestic cat: Protein sequence analysis and cDNA cloning
2. Expression and genomic structure of the gene encoding FdI, the major allergen from the domestic cat
3. A comparative study of the allergens of cat urine, serum, saliva and pelt
4. Cat skin as an important source of Fel d I allergen
5. Fel d I allergen distribution in cat fur and skin
6. Fel d I levels in cat anal glands
7. Effects of castration and testosterone on Fel d I production by sebaceous glands of male cats. I. Immunological assessment
8. Effects of castration and teststerone on Fel d I production by sebaceous glands of male cats: II-morphometric assessment
9. Monoclonal antibodies to the major feline allergen Fel d I. I. Serologic and biologic activity of affinity-purified Fel d I and Fel d I-depleted extract
10. Defining allegen of mammalian origin
11. High prevalence of sensitization to cat allergen among Japanese children with asthma, living without cats
12. Allergenically active components of cat allergen extracts
13. Identification and clinical significance of allergenic molecules of cat origin
14. Characterization of the main IgE-binding components of cat dander
15. Bronchial provocation with cat allergen. Correlation between the individual IgE-CRIE pattern and the occurrence of a late allergic reaction
16. Monoclonal antibodies against Fel d I and other clinically relevant cat allergens
17. Monoclonal antibody-standardized cat extract immunotherapy: Risk-benefit effects from a double-blind placebo study
18. Cloning of cockroach allergen, Bla g 4, identifies ligand binding proteins (or calycins) as a cause of IgE antibody responses
19. Induction of IgE antibody responses by glutathione-S-transferase from the German cockroach (Blattella germanica)
20. Protein modelling by E-mail
21. ProMod and Swiss-Model: Internet-based tools for automated comparative protein modelling
22. Swiss-Model and the Swiss-Pdb viewer: An environment for comparative protein modelling
23. Solution structure of a human cystatin A variant, cystatin A2-98 M65L, by NMR spectroscopy. A possible role of the interactions between N- and C-termini to maintain the inhibitory active form of cystatin A
24. The three-dimensional solution structure of human stefin A
25. The refined 2.4 Å X-ray crystal structure of recombinant human stefin B in complex with the cysteine protease papain: A novel type of proteinase inhibitor interaction
26. The major dog allergens, Can f 1 and Can f 2, are salivary lipocalin proteins: Cloning and immunological characterization of recombinant forms
27. The salivary lipocalin von Ebner's gland protein is a cysteine protease inhibitor
28. Sequence of the gene encoding cat (Felis domesticus) serum albumin
29. The cystatins. Protein inhibitors of cysteine proteases
30. Human cysteine-protease inhibitors. Nucleotide sequence analysis of three members of the cystatin gene family
31. Identification of bovine tefin A, a novel protein inhibitor of cysteine proteinases
32. The cystatins. A new class of peptidase inhibitors
33. Allergy to lipocalins: A consequence of misguided T-cell recognition of self and nonself?
34. Allergy to mammalian proteins at the borderline between foreign and self?
35. Der p I, a major allergen of the house dust mite, proteolytically cleaves the low-affinity receptor for human IgE (CD23)
36. A major house dust mite allergen disrupts the immunoglobulin E network by selectively cleaving CD 23: Innate protection by antiproteases
37. Proteolytic cleavage of CD25, the α-subunit of human T cell interleukin 2 receptor, Der p 1, major mite allergen with cysteine protease activity
38. Dust mite proteolytic allergens induced cytokine release from cultured airway epithelium
39. Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions
40. A mite subversive: Cleavage of CD23 and CD25 by Der p 1 enhances allergenicity
41. The proteolytic activity of Der p 1 selectively enhances IgE synthesis: A link between allergenicity and cysteine protease activity
42. Sensitization, asthma, and a modified Th2 response in children exposed to cat allergen: A population based cross-sectional study
43. Purified natural and recombinant Fel d 1 and cat albumin in in vitro diagnostics for cat allergy
44. Recombinant allergens for diagnosis and therapy of allergic disease