The CRP-cAMP complex and downregulation of the glnAP2 promoter provides a novel regulatory linkage between carbon metabolism and nitrogen assimilation in Escherichia coli

Molecular Microbiology

Volumn 41, Issue 4, 2001, Pages 911-924

  Tian, Zhe Xian ^a   Li, Quan Sheng ^a   Buck, Martin ^b   Kolb, Annie ^c   Wang, Yi Ping ^a,c  

^a PEKING UNIVERSITY   (China)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CYCLIC AMP; CYCLIC AMP BINDING PROTEIN; GAMMA GLUTAMYLTRANSFERASE; GLUTAMATE AMMONIA LIGASE; NITROGEN; PERMANGANATE POTASSIUM;

ARTICLE; CARBON METABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; GENETIC LINKAGE; NITROGEN FIXATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULON; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION REGULATION;

CARBON; CYCLIC AMP; CYCLIC AMP RECEPTOR PROTEIN; DNA FOOTPRINTING; DNA-BINDING PROTEINS; DNA-DIRECTED RNA POLYMERASES; DOWN-REGULATION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; GLUTAMATE-AMMONIA LIGASE; HSP70 HEAT-SHOCK PROTEINS; MUTAGENESIS; NITROGEN; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RNA POLYMERASE SIGMA 54; SIGMA FACTOR; TRANSCRIPTION, GENETIC;

ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0035724135     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2001.02561.x     Document Type: Article

References (56)

1. Mutations that alter the ability of the Escherichia coli cyclic AMP receptor protein to activate transcription
2. Biochemical parameters of glutamine synthetase from Klebsiella aerogenes
3. Selection of DNA binding sites by regulatory proteins
4. Selection of DNA-binding sites by regulatory proteins. II. The binding specificity of cyclic AMP receptor protein to recognition sites
5. Active recruitment of sigma54-RNA polymerase to the Pu promoter of Pseudomonas putida: Role of IHF and alphaCTD
6. Regulatory circuits for plasmid survival
7. Positive selection for loss of tetracycline resistance
8. Upstream activator sequences are present in the promoters of nitrogen fixation genes
9. Transcription activation by catabolite activator protein (CAP)
10. Ntr (PtsN) protein of Pseudomonas putida mediates the C source inhibition of the σ54-dependent Pu promoter of the TOL plasmid
11. Amino acid sequence of Escherichia coli glutamine synthetase deduced from the DNA nucleotide sequence
12. Plasmids related to the broad host range vector, pRK290, useful for gene cloning and for monitoring gene expression
13. Ntr protein of the phosphotransferase system in Escherichia coli
14. Regulation of Escherichia coli adenylate cyclase activity during hexose phosphate transport
15. Adenosine 3′: 5′-cyclic monophosphate as mediator of catabolite repression in Escherichia coli
16. Catabolite repression by glucose 6-phosphate, gluconate and lactose in Escherichia coli
17. The central domain of Rhizobium meliloti NifA is sufficient to activate transcription from the R. meliloti nifH promoter
18. The central domain of Rhizobium leguminosarum DctD functions independently to activate transcription
19. Growth-phase-dependent expression of the Pseudomonas putida TOL plasmid pWW0 catabolic genes
20. Mechanism responsible for glucose-lactose diauxie in Escherichia coli: Challenge to the cAMP model
21. Regulation of RNA polymerase sigma subunit synthesis in Escherichia coli: Intracellular levels of four species of sigma subunit under various growth conditions
22. Molecular analysis of the operon which encodes the RNA polymerase sigma factor sigma 54 of Escherichia coli
23. Sequence of the lacZ gene of Escherichia coli
24. Transcriptional regulation by cAMP and its receptor protein
25. Expression of sigma 54 (ntrA)-dependent genes is probably united by a common mechanism
26. The C terminus of the alpha subunit of RNA polymerase is not essential for transcriptional activation of sigma 54 holoenzyme
27. Fine-structure deletion map and complementation analysis of the ntrA-glnL-glnG region in Escherichia coli
28. The products of glnL and glnG are bifunctional regulatory proteins
29. Regulation of nitrogen utilization
30. In a class of its own - The RNA polymerase sigma factor sigma 54 (sigma N)
31. Mutations in genes downstream of the rpoN gene (encoding sigma 54) of Klebsiella pneumoniae affect expression from sigma (54)-dependent promoters
32. The DNA-binding domain of the transcriptional activator protein NifA resides in its carboxyl terminus, recognizes the upstream activator sequences of nif promoters and be separated from the positive control function of NifA
33. Construction of improved M13 vectors by oligonucleotide-directed mutagenesis
34. ts mutant
35. ntr from Escherichia coli: A novel enzyme of the phosphoenolpyruvate-dependent phosphotransferase system exhibiting strict specificity for its phosphoryl acceptor, Npr
36. Expression of glnA in Escherichia coli is regulated at tandem promoters
37. Transcription of glnA in E. coli is stimulated by activator bound to sites far from the promoter
38. A proposed link between nitrogen and carbon metabolism involving protein phosphorylation in bacteria
39. Novel phosphotransferase-encoding genes revealed by analysis of the Escherichia coli genome: A chimeric gene encoding an enzyme I homologue that possesses a putative sensory transduction domain
40. Aspects of the regulation of adenylate cyclase synthesis in Escherichia coli K12
41. Regulation of adenylate cyclase synthesis in Escherichia coli: Nucleotide sequence of the control region
42. Regulation of carbon utilization
43. Point mutations change the thermal denaturation profile of a short DNA fragment containing the lactose control elements. Comparison between experiment and theory
44. Role of multiple environmental stimuli in control of transcription from nitrogen-regulated promoter in Escherichia coli with weak or no activator-binding sites
45. Multiple molecular forms of glutamine synthetase produced by enzyme catalyzed adenylylation and deadenylylation reactions
46. Role of cyclic AMP in bacteria
47. The Escherichia coli cAMP receptor protein (CRP) represses the Rhizobium meliloti dctA promoter in a cAMP-dependent fashion
48. 54 RNA polymerase and blocks transcriptional activation of the dctA promoter
49. The tetracycline resistance determinants of RP1 and Tn1721: Nucleotide sequence analysis
50. Effect of nifA product on suppression of Nif-phenotype of gln mutation and constitutive synthesis of nitrogenase in Klebsiella
51. Nitrogen regulatory protein C-controlled genes of Escherichia coli: Scavenging as a defense against nitrogen limitation