Confocal examination of nonmelanoma cancers in thick skin excisions to potentially guide mohs micrographic surgery without frozen histopathology

Journal of Investigative Dermatology

Volumn 117, Issue 5, 2001, Pages 1137-1143

  Rajadhyaksha, Milind ^a,b   Menaker, Gregg ^b   Flotte, Thomas ^b   Dwyer, Peter J ^a   González, Salvador ^b  

^a Lucid Inc   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Dermatology; Lasers; Optical imaging; Optical microscopy; Scanning; Surgical pathology

Indexed keywords

ACETIC ACID;

ARTICLE; CELL NUCLEUS; CELL STRUCTURE; CHEMOSURGERY; CHROMATIN; CONFOCAL REFLECTANCE MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DEPOLARIZATION; DERMIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; MICROSCOPE; MICROSCOPY; MICROSURGERY; OPERATION DURATION; POLARIZATION; PRIORITY JOURNAL; SKIN CARCINOMA; SURGEON; THICKNESS;

EID: 0035724046     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-202X.2001.01524.x     Document Type: Article

References (27)

1. In vivo spatio-temporal visualization of the human skin by real-time confocal microscopy
2. Differential light scattering from spherical mammalian cells
3. Über die atypische umwandlungszone
4. In vivo vision of the human skin with the tandem scanning microscope
5. Morphometry of human epidermis in vivo by real-time confocal microscopy
6. In vivo confocal microscopy of human skin: A new design for cosmetology and dermatology
7. Optical polarization imaging
8. Time-resolved degree of polarization for human breast tissue
9. Laser scanning confocal microscopy of cervical tissue before and after application of acetic acid
10. The effect of different fixatives on chromatin: Cytochemical and ultrastructural approaches
11. Confocal microscopy: A new tool for the study of the nail unit
12. Polarization memory of multiply scattered light
13. New light on skin cancer mechanisms
14. Three-dimensional microscopic biopsy of in vivo human skin: A new technique based on a flexible confocal microscope
15. Rapid observation of unfixed, unstained human skin biopsy specimens with confocal microscopy and visualization
16. Chemosurgery - A microscopically controlled method of cancer excision
17. In vivo imaging of human teeth and skin using real-time confocal microscopy
18. In vivo confocal scanning laser microscopy of human skin: Melanin provides strong contrast
19. In vivo confocal scanning laser microscopy of human skin II. Advances in instrumentation and comparison with histology
20. Video-rate confocal scanning laser microscope for imaging human tissues in vivo
21. Use of polarized light to discriminate short-path photons in a multiply scattering medium
22. Near real-time confocal microscopy of cultured amelanotic cells: Sources of signal, contrast agents and limits of contrast
23. Determination of the refractive index of highly scattering human tissue by optical coherence tomography