De-escalation antimicrobial chemotherapy in critically ill patients: Pros and cons

Journal of Chemotherapy

Volumn 13, Issue SPEC. ISS. 1, 2001, Pages 218-223

  Antonelli, Massimo ^a   Mercurio, G ^a   Di Nunno, S ^a   Recchioni, G ^a   Deangelis, G ^a  

^a FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

Author keywords

Carbapenems; De escalation antimicrobial chemotherapy; Glycopeptides; Sepsis; Ventilator associated pneumonia

Indexed keywords

ANTIBIOTIC AGENT; BETA LACTAMASE INHIBITOR; CARBAPENEM DERIVATIVE; CEFTAZIDIME; CLOXACILLIN; GLYCOPEPTIDE; IMIPENEM; MEROPENEM; METICILLIN; TAZOBACTAM; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; BACTERIAL INFECTION; BACTERIAL PNEUMONIA; BACTERIUM IDENTIFICATION; CLINICAL FEATURE; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONFERENCE PAPER; CRITICAL ILLNESS; DEESCALATION ANTIMICROBIAL CHEMOTHERAPY; DISEASE SEVERITY; DRUG CHOICE; DRUG CONTRAINDICATION; DRUG INDICATION; ENTEROCOCCUS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HOSPITAL COST; HOSPITAL INFECTION; HUMAN; INFECTION RATE; INTENSIVE CARE; INTENSIVE CARE UNIT; LENGTH OF STAY; MEDICAL LITERATURE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MONOTHERAPY; NEPHROTOXICITY; OTOTOXICITY; PATIENT SELECTION; SEPSIS; STAPHYLOCOCCUS; STAPHYLOCOCCUS EPIDERMIDIS;

EID: 0035721832     PISSN: 1120009X     EISSN: None     Source Type: Journal    
DOI: 10.1179/joc.2001.13.supplement-2.218     Document Type: Conference Paper

References (35)

1. Nosocomial bloodstream infections in critically ill patients. Excess length of stay, extra cost, and attributable mortality
2. Nosocomial infections in combined medical-surgical Intensive Care Units in the United States
3. Long-term survival following bacteremia or fungemia
4. The systemic inflammatory response syndrome as predictor of bacteraemia and outcome from sepsis
5. The value of routine microbial investigation in ventilator-associated pneumonia
6. The threat of vancomycin resistance
7. The incidence of and clinical variables associated with vancomycin-resistant enterococcal colonization in mechanically ventilated patients
8. Bacterial pathogens isolated from patients with bloodstream infection: Frequencies of occurrence and antimicrobial susceptibility patterns from the Sentry Antimicrobial Surveillance Program
9. Nosocomial pneumonia: A multivariate analysis of risk and prognosis
10. Pneumonia caused by gram-negative bacilli
11. Impact of BAL data on the therapy and outcome of ventilator-associated pneumonia
12. Problem pathogens (Pseudomonas aeruginosa and Acinetobacter)
13. Clinical and molecular epidemiology of Acinetobacter infections sensitive only to polymyxin B and sulbactam
14. Nosocomial bloodstream infections caused by Acinetobacter species in United States Hospitals: Clinical features, molecular epidemiology and antimicrobial susceptibility
15. Meropenem versus imipenem/cilastatin as empirical monotherapy for serious bacterial infections in the intensive care unit
16. Efficacy of meropenem as monotherapy in the treatment of ventilator-associated pneumonia
17. Comparison of serum bactericidal activity of ceftazidime, ciprofloxacin and meropenem against Sternotrophomonas maltophilia
18. Antibiotic susceptibility among aerobic gram-negative bacilli in Intensive Care Units in 5 European countries
19. Carbapenems in clinical practice: A guide to their use in serious infection
20. The influence of inadequate antimicrobial treatment of bloodstream infections on patient cutcomes in the ICU setting
21. Hospital-acquired pneumonia in adults: Diagnosis, assessment of severity, initial antimicrobial therapy, and preventive strategies
22. Bacteremic pneumonia due to Staphylococcus aureus: A comparison of disease caused by methicillin-resistant and methicillin- susceptible organisms
23. Ventilator-associated pneumonia by Staphylococcus aureus: Comparison of methicillin-resistant and methicillin-sensible episodes
24. Pulmonary disposition of vancomycin in critically ill patients
25. Mortality associated with nosocomial bacteremia due to methicillin resistant Staphylococcus aureus
26. Variations in etiology of ventilator-associated pneumonia across four treatment sites. Implications for antimicrobial prescribing practices
27. Antimicrobial resistance in nosocomial isolates of Staphylococcus haemolyticus
28. Peritonitis due to vancomycin-resistant Staphylococcus epidermidis
29. Percentages and distributions of teicoplanin- and vancomycin-resistant strains among coagulase-negative staphylococci
30. Update on clinical significance of coagulase-negative staphylococci
31. Risks factors for mortality associated with enterococcal bloodstream infections
32. Enterococcal bacteremia in the surgical intensive care unit: Does vancomycin resistance affect mortality?
33. Stool carriage, clinical isolation, and mortality during an outbreak of vancomycin-resistant enterococci in hospitalized medical and/or surgical patients
34. Cerebrospinal fluid penetration and pharmacokinetics of vancomycin administered by continuous infusion to mechanically ventilated patients in an intensive care unit
35. Continuous infusion of vancomycin in methicillin-resistant Staphylococcus infection