Principles of effectiveness trials and their implementation in VA Cooperative Study #430: 'Reducing the Efficacy-Effectiveness Gap in Bipolar Disorder'

Journal of Affective Disorders

Volumn 67, Issue 1-3, 2001, Pages 61-78

  Bauer, Mark S ^a,b,j   Williford, William O ^c   Dawson, Erinn E ^a   Akiskal, Hagop S ^d   Altshuler, Lori ^e   Fye, Carol ^f   Gelenberg, Alan ^g   Glick, Henry ^h   Kinosian, Bruce ^h   Sajatovic, Martha ⁱ  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b BROWN UNIVERSITY   (United States)

^c VA Cooperative Studies Coordinating Center   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f University of New Mexico   (United States)

^g UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^h UNIVERSITY OF PENNSYLVANIA   (United States)

ⁱ CASE WESTERN RESERVE UNIVERSITY   (United States)

^j BROWN UNIVERSITY   (United States)

more..

Author keywords

Bipolar disorder; Clinical trial; Costs and cost analysis (cost benefit analysis); National Institute of Mental Health; Outcome assessment (health care); United States Department of Veterans Affairs

Indexed keywords

ALGORITHM; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST OF ILLNESS; HEALTH CARE DELIVERY; HUMAN; HYPOTHESIS; INTERMETHOD COMPARISON; MANIC DEPRESSIVE PSYCHOSIS; MEDICAL RESEARCH; MENTAL DISEASE; MENTAL HEALTH; PATIENT EDUCATION; PRIMARY HEALTH CARE; PRIORITY JOURNAL; QUALITY CONTROL; STATISTICS; TREATMENT OUTCOME; VALIDATION PROCESS;

ACTIVITIES OF DAILY LIVING; ADULT; ALGORITHMS; BIPOLAR DISORDER; CONTINUITY OF PATIENT CARE; ENDPOINT DETERMINATION; FEMALE; HUMANS; MALE; MENTAL HEALTH SERVICES; MIDDLE AGED; PATIENT EDUCATION; PATIENT SELECTION; RANDOMIZED CONTROLLED TRIALS; RESEARCH DESIGN; TREATMENT OUTCOME;

EID: 0035719934     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0327(01)00440-2     Document Type: Article

References (90)

1. Lithium as a prophylactic agent: Its effect against recurrent depression and manic-depressive psychosis
2. Quantitative adherence studies of mental health clinical practice guidelines
3. Validity of rapid cycling as a modifier for bipolar disorder in DSM-IV
4. Impact of an easy-access VA clinic-based program for patients with bipolar disorder: Quantitative analysis of demonstration project
5. Predictors of service utilization in veterans with bipolar disorder: A prospective study
6. Manual-based group psychotherapy for bipolar disorder: A feasibility study
7. Clinical practice guidelines for bipolar disorder from the Department of Veterans Affairs
8. Correlates of functional and economic outcome in bipolar disorder: A prospective study
9. Social adjustment of remitted bipolar and unipolar out-patients: A comparison with age- and sex-matched controls
10. Efficacy of divalproex versus lithium and placebo in the treatment of mania
11. Assertive community treatment: An update of randomized trials
12. Spectrum of efficacy of valproate in 55 patients with rapid-cycling bipolar disorder
13. Follow-up of 53 bipolar manic depressive patients
14. Regional variations in the use of common surgical services by the medicare population
15. Prophylactic lithium in affective disorders: Controlled trial
16. Bipolar II illness: Course and outcome over a 5-year period
17. Does maintenance lithium prevent recurrences of mania under ordinary clinical conditions?
18. Symptoms and functioning of patients with bipolar disorder 6 months after hospitalization
19. Clinical factors in lithium carbonate prophylaxis failure
20. Clinical economics: A guide to economic analysis of clinical practice
21. A case manager intervention to reduce readmissions
22. Variations among VA hospitals in length of stay for treatment of depression
23. The relationship between antimanic agent for treatment of classic or dysphoric mania and length of hospital stay
24. Assessment of social adjustment in chronic ambulatory schizophrenics
25. Lithium response in unipolar versus bipolar depression
26. The community psychiatric nurse in primary care: An economic analysis
27. Outcome in manic disorders: A naturalistic follow-up study
28. Lithium use and discontinuation in a health maintenance organization
29. Factors associated with pharmocologic non-compliance in patients with mania
30. Twelve-month outcome of patients with bipolar disorder following hospitalization for a manic or mixed episode
31. Differential outcome of episodes of illness in bipolar patients: Pure manic, mixed/cycling, and pure depressive
32. Low levels and lack of predictors of somatotherapy and psychotherapy received by depressed patients
33. The longitudinal interval follow-up evaluation: A comprehensive method for assessing outcome in prospective longitudinal studies
34. Measuring the need for mental health care
35. A multiple imputation strategy for clinical trials with truncation of patient data
36. Intent-to-treat analysis for longitudinal studies with drop-outs
37. Treatment of manic illness with lithium carbonate
38. Lithium discontinuation: A 5-year follow-up study
39. Previous pattern of course of the illness as a predictor of response to lithium prophylaxis in bipolar illness
40. Diagnosis change, lithium use, and admissions for mania in Edinburgh
41. Cost-effectiveness of community psychiatric nurse or out-patient psychiatrist care of neurotic patients
42. Efficacy of lithium prophylaxis in clinical practice
43. The impact of lithium in South-West Scotland. III. The discontinuation of lithium
44. Lithium in the treatment of depression
45. The impact of lithium in South-West Scotland. II. A longitudinal study
46. Recovery after 5 years of unremitting major depressive disorder
47. Comprehensive discharge planning for the hospitalized elderly: A randomized clinical trial
48. Psychopathology during long-term lithium treatment of patients with major affective disorders: A prospective study
49. Outcome of bipolar disorder on long-term treatment with lithium
50. Comparison of the antimanic efficacy of carbamazepine and chlorpromazine: A double-blind controlled study
51. A preliminary double-blind study on the efficacy of carbamazepine in prophylaxis of manic-depressive illness
52. Assertive community treatment: An evaluation of the experimental evidence
53. Changes in the diagnoses of the functional psychoses associated with the introduction of lithium
54. Valproate in the treatment of acute mania
55. Correlates of antimanic responses to carbamazepine
56. Alternatives to lithium for the preventive treatment of bipolar disorder
57. National Institute of Mental Health workshop report on the treatment of bipolar disorder
58. Factors associated with treatment success in lithium carbonate prophylaxis: Report of the Veterans Administration and National Institute of Mental Health Collaborative Study Group
59. Lithium: A brake in the rising cost of mental illness
60. Multisite experimental cost study of intensive psychiatric community care
61. Lithium: Miracle, myth, and misunderstanding
62. The treatment of manic psychoses by administration of lithium salts
63. The effects of an ambulatory collaborative practice model on process and outcome of care for bipolar disorder
64. Case management in psychiatry: An analysis of tasks
65. Post-discharge care and readmissions
66. Alternative to mental hospital treatment. I. Conceptual model, treatment program, and clinical evaluation
67. Twelve-month outcome after a first hospitalization for affective psychosis
68. Inappropriate use of hospitals in a randomized trial of health insurance plans
69. Lithium and the changing incidence of mania
70. Alternative to mental hospital treatment. III. Social cost
71. Outcome in mania: A 4-year prospective follow-up of 75 patients utilizing survival analysis
72. Strategies to reduce hospital readmissions. A review
73. Does increased access to primary care reduce hospital readmissions?
74. Alternative to mental hospital treatment. II. Economic benefit-cost analysis
75. Treatment research at the crossroads: The scientific interface of clinical trials and effectiveness research
76. Small area variations in health care delivery
77. Professional uncertainty and the problem of supplies-induced demand