Functional analysis of the putative peroxidase domain of FANCA, the fanconi anemia complementation group A protein

Molecular Genetics and Metabolism

Volumn 72, Issue 1, 2001, Pages 54-60

  Ren, Jie ^a   Youssoufian, Hagop ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Crosslinker; Fanconi anemia; Mutagenesis; Peroxidase

Indexed keywords

GENE PRODUCT; HEMOPROTEIN; MITOMYCIN C; PEROXIDASE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; BIRTH DEFECT; BONE MARROW DEPRESSION; CANCER SUSCEPTIBILITY; CELLULAR DISTRIBUTION; CHROMOSOME BREAKAGE; CONTROLLED STUDY; CROSS LINKING; FANCONI ANEMIA; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS;

EID: 0035718305     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1006/mgme.2000.3109     Document Type: Article

References (21)

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4. Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA
5. The Fanconi anaemia/Breast cancer consortium: Positional cloning of the Fanconi anaemia group A gene
6. The Fanconi anaemia group G gene FANCG is identical with XRCC9
7. The Fanconi anaemia gene FANCF encodes a protein with homology to ROM
8. Localization of Fanconi anemia C protein to the cytoplasm of mammalian cells
9. Identification of cytosolic proteins that bind to the Fanconi anemia complementation group C polypeptide in vitro
10. Cytoplasmic localization of FAC is essential for the correction of a prerepair defect in Fanconi Anemia group C cells
11. Abnormal microsomal detoxification implicated in Fanconi anemia group C by interaction of the FAC protein with NADPH cytochrome P450 reductase
12. Fine exon-intron structure of the fanconi anemia group A (FAA) gene and characterization of two genomic deletions
13. The Fanconi anemia proteins FAA and FAC function in different cellular compartments to protect against cross-linking agent cytotoxicity
14. The Fanconi anemia complementation group A protein contains a peroxidase domain
15. A physical complex of the Fanconi Anemia proteins FANCG/XRCC9 and FANCA
16. Resistance to Mitomycin C requires direct interaction between the Fanconi anemia proteins FANCA and FANCG in the nucleus through an arginine-rich domain
17. Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite
18. Nucleotide sequence of the human gamma cytoskeletal actin mRNA: Anomalous evolution of vertebrate non-muscle actin genes
19. Induction of heme oxygenase: A general response to oxidant stress in cultures mammalian cells
20. Cloning and characterization of murine fanconi anemia group A gene: Fanca protein is expressed in lymphoid tissues, testis, and ovary
21. Cloning and analysis of the mouse Fanconi anemia group A cDNA and an overlapping penta zinc finger cDNA