Cardiovascular and neurohormonal responses to i. v. l-arginine in two groups with primary autonomic failure

Journal of Neurology

Volumn 248, Issue 12, 2001, Pages 1036-1041

  Kimber, J ^b   Watson, L ^b   Mathias, C J ^a  

^a ST MARY S HOSPITAL   (United Kingdom)

^b NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

Autonomic failure; L arginine; Neurohormonal

Indexed keywords

ADRENALIN; ARGININE; DOPAMINE; GLUCOSE; INSULIN; NEUROHORMONE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NORADRENALIN;

ADULT; AGED; ARTICLE; AUTONOMIC DYSFUNCTION; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR RESPONSE; CATECHOLAMINE BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FEMALE; GLUCOSE BLOOD LEVEL; HEART RATE; HORMONE RELEASE; HUMAN; INFUSION; INSULIN BLOOD LEVEL; INSULIN RELEASE; MALE; MEAN ARTERIAL PRESSURE; NORADRENALIN BLOOD LEVEL; ORTHOSTATIC HYPOTENSION; PRIORITY JOURNAL; SHY DRAGER SYNDROME; SYMPATHETIC TONE; SYSTOLIC BLOOD PRESSURE; VASODILATATION;

ADULT; AGED; ARGININE; AUTONOMIC NERVOUS SYSTEM DISEASES; BLOOD GLUCOSE; BLOOD PRESSURE; CATECHOLAMINES; FEMALE; HEART RATE; HEMODYNAMIC PROCESSES; HUMANS; INFUSIONS, INTRAVENOUS; INSULIN; MALE; MIDDLE AGED; MULTIPLE SYSTEM ATROPHY; NEUROTRANSMITTER AGENTS;

EID: 0035711108     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004150170022     Document Type: Article

References (36)

1. Effects of endothelium-derived nitric oxide an peripheral arteriolar tone in man
2. Sympathetic nerve traffic correlates with the release of nitric oxide in humans; implication for BP control
3. Hypertension in mice lacking the gene for endothelial nitric oxide
4. Inhibition of nitric oxide synthesis increases BP in healthy humans
5. L-arginine induced hypotension
6. L-arginine administration on haemodynamics and nitric oxide release in man
7. L-arginine infusion induces hypotension and diuresis/natriuresis with concomitant increased urinary excretion of nitrate/nitrite and cAMP in humans
8. L-arginine infusion decreases peripheral arteriolar resistance and inhibits platelet aggregation in healthy subjects
9. Haemodynamic and biochemical responses to l-arginine and l-lysine infusions in normal subjects: L-arginine induced vasodilatation cannot be explained by non-specific effects of amino-acids
10. The humoral, renal and pressor effects of systemic l-arginine infusion in hypertensive subjects
11. L-arginine infusion has no effect on systemic haemodynamics in normal volunteers, or systemic and pulmonary haemodynamics in patients with elevated pulmonary vascular resistance
12. Vascular and hormonal responses to arginine: Provision of substrate for nitric oxide or non-specific effect
13. Nitric oxide synthase isozymes; characterisation, purification, molecular cloning and functions
14. The vascular effects of L-arginine in humans. The role of endogenous insulin
15. Neuropharmacological investigation of autonomic failure
16. Investigation of autonomic disorders
17. Disorders of the autonomic nervous system
18. Role of nitric oxide in regulation of the baroreceptor reflex
19. Role of nitric oxide in the regulation of cardiovascular autonomic control
20. Is nitric oxide involved in tonic inhibition of central sympathetic outflow in humans
21. Regulation of nitric oxide synthesis by endogenous dimethylarginine
22. Neurally mediated syncope: Pathogenesis, diagnosis, and treatment
23. The role of endogenous nitric oxide in human septic shock
24. Nitric oxide and exercise-induced hypotension in human sympathetic denervation
25. Insulin secretion from pancreatic β-cells caused by l-arginine-derived nitric oxide
26. Arginine stimulated acute phase of insulin and glucagon secretion. I. In normal man
27. Effects of hyperinsulinaemia on the cardiovascular responses to graded hypovolaemia in normal and diabetic subjects
28. Insulin-mediated skeletal muscle vasodilatation is NO-dependent. A novel action of insulin to increase nitric oxide release
29. The effects of the somatostatin analogue octreotide on postural hypotension, before and after food ingestion
30. The influence of the autonomic nervous system on metabolic function
31. Hyperinsulinaemia produces both sympathetic neural activation and vasodilation in normal humans
32. Acute effect of insulin on autonomic regulation of the cardiovascular system; a study by heart rate spectral analysis
33. Insulin induced hypotension and neurogenic orthostatic hypotension
34. Postprandial hypotension in autonomic disorders
35. Mechanisms of arterial hypotension alter therapeutic dose of subcutaneous insulin in diabetic autonomic neuropathy
36. Distinction of IPD from MSA by stimulation of growth hormone release with clonidine