Distinction of idiopathic Parkinson's disease from multiple-system atrophy by stimulation of growth-hormone release with clonidine

Lancet

Volumn 349, Issue 9069, 1996, Pages 1877-1881

  Kimber, J R ^a   Watson, L ^a   Mathias, C J ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CLONIDINE; FLUDROCORTISONE ACETATE; GROWTH HORMONE; LEVODOPA;

ADULT; AGED; ARTICLE; AUTONOMIC DYSFUNCTION; CONTROLLED STUDY; DEGENERATIVE DISEASE; DIFFERENTIAL DIAGNOSIS; GROWTH HORMONE BLOOD LEVEL; GROWTH HORMONE RELEASE; HUMAN; HYPOPHYSIS; IDIOPATHIC DISEASE; MAJOR CLINICAL STUDY; NERVE CELL; PARKINSONISM; PRIORITY JOURNAL; PROGNOSIS; SHY DRAGER SYNDROME; SOMATIC CELL;

EID: 0030604553     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(96)10168-9     Document Type: Article

References (29)

1. 1 Schoenberg BS. Epidemiology of movement disorders. In: Marsden CD, Fahn S, eds. Movement disorders II. Oxford: Butterworth-Heinemann, 1987: 17-31.
2. 2 Bannister R, Mathias CJ, Polinsky R. Autonomic Failure: a comparison between UK and US experience. In: Bannister R, ed. Autonomic failure; a textbook of clinical disorders of the autonomic nervous system. 2nd edn. Oxford: Oxford University Press, 1988: 281-88.
3. 3 Colisimo C, Albanese A, Hughes AJ, De Bruin V, Lees A. Some specific features differentiate MSA (striato-nigral degeneration) from IPD. Arch Neurol 1995; 52: 294-98.
4. 4 Consensus statement: definition of orthostatic hypotension, pure autonomic failure and multiple system atrophy. Clin Auton Res 1996; 6: 125-26.
5. 5 Mathias CJ, Williams A. The Shy-Drager syndrome and multiple system atrophy. In: Calne D, ed. Neurodegenerative disorders. Philadelphia: W B Saunders, 1994: 743-67.
6. 6 Spencer DD, Robbins R, Naftolin F, et al. Unilateral transplantation of fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease. N Engl J Med 1992; 327: 1541-95.
7. 7 Mathias CJ, Bannister R. Investigation of autonomic disorders. In: Bannister R, Mathias CJ, eds. Autonomic failure; a textbook of clinical disorders of the autonomic nervous system. 3rd edn. Oxford: Oxford University Press, 1992: 255-90.
8. 8 Eardley I, Quinn N, Fowler CJ et al. The value of urethral sphincter EMG in the differential diagnosis of Parkinsonism. Br J Urol 1989; 64: 360-62.
9. 9 Brooks DJ, et al. Differing patterns of striatal 18F-dopa uptake in Parkinson's disease, MSA and progressive supranuclear palsy. Ann Neurol 1991; 28: 547-55.
10. 10 Fulham MJ, Dubinsky R, Polinsky R, et al. Computed tomography with 18F fluorodeoxyglucose in multiple system atrophy and pure autonomic failure. Clin Auton Res 1992; 1: 27-36.
11. 11 Davie CA, Wenning G, Barker G, et al. Differentiation of MSA from IPD using proton magnetic resonance spectroscopy. Ann Neurol 1995; 37: 204-21.
12. 12 Thomiades TN, Ray Chaudhiri K, Maule S, Watson L, Marsden CD, Mathias CJ. Growth hormone response to clonidine in central and peripheral autonomic failure. Lancet 1992; 340: 263-66.
13. 13 Mathias CJ. Disorders of the autonomic nervous system. In: Bradley WG, Daroff RB, Fenichel GM, Marsden CD, eds. Neurology in clinical practice. 2nd edn. Boston: Butterworth-Heinemann, 1996: 1953-81.
14. 14 Gibb WR, Lees AJ. The relevance of the Lewy body in the pathogenesis of IPD (a review). J Neurol Neurosurg Psychiatry 1988; 51: 745-52.
15. 15 Hoehn MM, Yahr MD. Parkinsonism; onset, progression and mortality. Neurology 1967; 17: 427-67.
16. 16 Polinsky RJ. Neuropharmacological investigation of autonomic failure. In: Bannister R, Mathias CJ, eds. A textbook of clinical disorders of the autonomic nervous system. 3rd edn. Oxford: Oxford University Press 1992; 334-58.
17. 17 Frohman LA, Downs TR. Measurement of GHRF. Methods Enzymol 1986; 124: 371-89.
18. 18 Mathias CJ, Bannister R, Cortelli P, et al. Clinical, autonomic and biochemical observations in two siblings with postural hypotension and sympathetic failure due to an inability to synthetise noradrenaline from dopamine because of a deficiency of dopamine-B-hydroxylase. QJM 1990; 75: 617-33.
19. 19 Rudolf CD, Kaplan SL, Ganong WF. Sites at which clonidine acts to affect blood pressure and the secretion of renin, GH and ACTH. Neuroendocrinology 1980; 31: 121-28.
20. 20 Al-Damluji S. Adrenergic control of anterior pituitary hormones. Ballieres Clin Endocrinol Metab 1993; 7: 355-92.
21. 21 Lightman S, Williams T. Hypothalamic and pituitary function in autonomic failure. In: Bannister R, Mathias CJ, eds. Autonomic failure; a textbook of clinical disorders of the autonomic nervous system. 3rd edn. Oxford: Oxford University Press, 1992: 378-90.
22. 22 Galea-Debono A, Jenner P, Marsden CD, Parkes J, Tarsy D, Walters J. Plasma DOPA levels and GH response to L-dopa in parkinsonism. J Neurol Neurosurg Psychiatry 1977; 40: 162-67.
23. 23 Chihara K, Yoichi K, Tetsuya K, et al. L-dopa stimulates release of GHRH in humans. J Clin Endocrinol Metab 1986; 62: 466-73.
24. 24 Sopwith A, Elizabeth S, Penny G, Besser G, Rees L. Stimulation by food of peripheral plasma immunoreactive growth hormone releasing factor. Clin Endocrinol 1985; 22: 337-40.
25. 25 Siler T, Yen S, Vale W, Guillemin R. Inhibition by somastatin on the release of TSH induced in man by thyrotropin-releasing factor. J Clin Endocrinol Metab 1974; 38; 742-45.
26. 26 Enjalbert A, Bertrand P, Le-Dafniet M, et al. Somastatin and regulation of prolactin secretion. Psychoneuroendocrinology 1986; 11: 155-65.
27. 27 Muller EE. Neural control of somatrophe function. Physiol Rev 1987; 67: 962-1053.
28. 28 Spokes EGS, Bannister R, Oppenheimer DR. Multiple system atrophy with autonomic failure: clinical, histological and neurochemical studies in 4 patients. J Neurol Sci 1979; 19: 275-86.
29. 29 Bluet-Pajot MT, Bertherat J, Epelbaum J, Kordon C. Neural and pituitary mechanisms involved in GH regulation. J Paediatr Res 1993; 6: 357-69.