The autosomal dominant trait of obesity, acanthosis nigricans, hypertension, ischemic heart disease and diabetes type 2

Hormone Research

Volumn 55, Issue 6, 2001, Pages 298-304

  Kerem, Nogah ^a   Guttmann, Hadassah ^a,b   Hochberg, Ze'ev ^a  

^a RAMBAM MEDICAL CENTER   (Israel)

^b MACCABI HEALTHCARE SERVICES   (Israel)

Author keywords

Acanthosis nigricans; Diabetes; Hypertension; Obesity

Indexed keywords

C PEPTIDE; CHOLESTEROL; FAT; GLUCOSE; HIGH DENSITY LIPOPROTEIN; INSULIN; LIPOPROTEIN;

ACANTHOSIS NIGRICANS; ADOLESCENCE; ADOLESCENT; ADULT; ADULTHOOD; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CHILDHOOD; CONTROLLED STUDY; DIET RESTRICTION; DISEASE COURSE; DISEASE MARKER; FAMILIAL DISEASE; FEMALE; GLUCOSE BLOOD LEVEL; HIGH RISK POPULATION; HUMAN; HYPERTENSION; INSULIN RESISTANCE; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; METABOLIC DISORDER; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; OVARY POLYCYSTIC DISEASE; PEDIGREE; PRIORITY JOURNAL; SCHOOL CHILD; WEIGHT REDUCTION;

ACANTHOSIS NIGRICANS; ADIPOSE TISSUE; ADOLESCENT; AGE OF ONSET; BLOOD GLUCOSE; CHILD; DIABETES MELLITUS, TYPE 2; FASTING; GENES, DOMINANT; HUMANS; HYPERTENSION; MALE; MYOCARDIAL ISCHEMIA; OBESITY; PEDIGREE; PROSPECTIVE STUDIES; SYNDROME;

EID: 0035701420     PISSN: 03010163     EISSN: None     Source Type: Journal    
DOI: 10.1159/000050017     Document Type: Article

References (17)

1. Acanthosis nigricans in obese women with hyperandrogenism. Characterization of acanthosis nigricans insulin-resistant state distinct from type A and B syndromes
2. Characterization of groups of hyperandrogenic women with acanthosis nigricans, impaired glucose tolerance and/or hyperinsulinemia
3. Acanthosis nigricans, insulin action and hyperandrogenism: Clinical histological and biochemical findings
4. Prevalence of acanthosis nigricans in acanthosis nigricans unselected population
5. Prevalence of acanthosis nigricans and its association with hyperinsulinemia in New Mexico adolescents
6. Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
7. Insulin sensitivity and its measurement: Structural commonalities among the methods
8. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
9. The human obesity gene map: The 1998 update
10. The inheritance of corpulence
11. Childhood onset (age less than 10) obesity has high familial risk
12. Assessment of insulin secretion in relatives of patients with type 2 (non-insulin-dependent) diabetes mellitus: Evidence of early beta-cell dysfunction
13. Evidence of a single gene effect causing polycystic ovaries and male pattern baldness
14. Polycystic ovaries are inherited as acanthosis nigricans autosomal dominant trait: Analysis of 29 polycyctic ovary syndrome and 10 control families
15. Adrenal androgen excess in the polycystic ovary syndrome: Sensitivity and responsivity of the hypothalamic-pituitary-adrenal axis
16. Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: A prospective controlled study in 254 affected women