Crth2: Marker for the detection of human th2 and tc2 cells

Advances in Experimental Medicine and Biology

Volumn 495, Issue , 2001, Pages 25-29

  Cosmi, Lorenzo ^a   Annunziato, Francesco ^a   Galli, Grazia ^a   Manetti, Roberto ^a   Maggi, Enrico ^a   Romagnani, Sergio ^a  

^a Department of Internal Medicine   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CHEMOATTRACTANT; CHEMOATTRACTANT RECEPTOR HOMOLOGOUS MOLECULE; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR4; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; LYMPHOCYTE SURFACE MARKER; UNCLASSIFIED DRUG;

CELL ISOLATION; CELL POLARITY; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH1 CELL; TH2 CELL;

BIOLOGICAL MARKERS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; HUMANS; RECEPTORS, CHEMOKINE; RECEPTORS, IMMUNOLOGIC; RECEPTORS, PROSTAGLANDIN; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, CYTOTOXIC; TH1 CELLS; TH2 CELLS;

EID: 0035699637     PISSN: 00652598     EISSN: None     Source Type: Journal    
DOI: 10.1007/978-1-4615-0685-0_4     Document Type: Article

References (8)

1. Specific expression of surface interferon-γ on interferon-γ-producing T cells from mouse and man
2. Expression and release of LAG-3-encoded protein by human CD4+ T cells are associated with 1FN-γ production
3. Differential expression of chemokine receptors and chemotactic responsiveness of Th1 and Th2 cells
4. Selective expression of a novel surface molecule by human Th2 cells in vivo
5. CRTH2, an orphan receptor of T-helper-2-cells, is expressd on basophils and eosinophils and responds to mast cell-derived factor(s)
6. CRTH2 is the most reliable marker for detection of circulating human type 2 Th and type 2 T cytotoxic cells in health and disease
7. Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils and basophils via seven-transmembrane receptor CRTH2