Co-grafts of fetal ventral mesencephalon and fibroblasts expressing Sonic hedgehog: Effect on survival and function of dopamine grafts

Cell Transplantation

Volumn 10, Issue 8, 2001, Pages 665-671

  Yurek, D M ^a   Fletcher Turner, A ^a   Moore, J ^a   Chai, L ^b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b CURIS INC   (United States)

Author keywords

Dopamine; Fetal ventral mesencephalon; Genetically modified fibroblasts; Neural transplantation; Parkinson's disease; Rodent; Sonic hedgehog

Indexed keywords

AMPHETAMINE; OXIDOPAMINE; SONIC HEDGEHOG PROTEIN;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL TRANSPLANTATION; DOPAMINERGIC NERVE CELL; FETAL TISSUE TRANSPLANTATION; FIBROBLAST; MALE; MESENCEPHALON; NERVE CELL; NERVE CELL TRANSPLANTATION; NEUROLOGIC DISEASE; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REINNERVATION; ROTATION; TREATMENT OUTCOME;

ANIMALIA; ERINACEIDAE; RODENTIA;

EID: 0035696416     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/000000001783986305     Document Type: Article

References (25)

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4. Induction of midbrain dopaminergic neurons by sonic hedgehog
5. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells
6. The importance of graft placement and task complexity for transplant-induced recovery of simple and complex sensorimotor deficits in dopamine denervated rats
7. Biochemical evidence that Patched is the Hedgehog receptor
8. Cloning, expression, and chromosomal location of SHH and IHH: Two human homologues of the Drosophila segment polarity gene hedgehog
9. Sonic hedgehog promotes the survival of specific CNS neuron populations and protects these cells from toxic insult in vitro
10. Induction of osteogenic differentiation by hedgehog proteins
11. Partial inhibition of Na+/K+-ATPase by ouabain induces the Ca2+-dependent expressions of early-response genes in cardiac myocytes
12. The product of hedgehog autoproteolytic cleavage active in local and long-range signalling
13. Glial cell line-derived neurotrophic factor increases survival, growth, and function of intrastriatal fetal nigral dopaminergic grafts
14. Brain-derived neurotrophic factor enhances function rather than survival of intrastriatal dopamine cell-rich grafts
15. GDNF enhances dopaminergic cell survival and fibre outgrowth in embryonic nigral grafts
16. Time course of apoptotic cell death within mesencephalic cell suspension grafts: Implications for improving grafted dopamine neuron survival
17. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
18. Normal rat cell lines deficient in nuclear thymidine kinase
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20. Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology
21. FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate
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23. Optimal effectiveness of BDNF for fetal nigral transplants coincides with the ontogenic appearance of BDNF in the striatum
24. Growth factors improve immediate survival of embryonic dopamine neurons after transplantation into rats