μ1A deficiency induces a profound increase in MPR300/IGF-II receptor internalization rate

Journal of Cell Science

Volumn 114, Issue 24, 2001, Pages 4469-4476

  Meyer, Christoph ^a   Eskelinen, Eeva Liisa ^a   Guruprasad, Medigeshi Ramarao ^a   von Figura, Kurt ^a   Schu, Peter ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

AP 1; Clathrin; Endocytosis; Exocytosis; MPR300 IGF II receptor

Indexed keywords

ADAPTOR PROTEIN; CLATHRIN; CYTOPLASMIC RECEPTOR; FUNCTIONAL GROUP; LYSOSOME ENZYME; SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL MEMBRANE; CELLULAR DISTRIBUTION; COATED VESICLE; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; FIBROBLAST; HOMEOSTASIS; HORMONE TRANSPORT; INTERNALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; PROTEIN TRANSPORT; RECEPTOR DENSITY; STEADY STATE; TRANS GOLGI NETWORK;

ADAPTOR PROTEIN COMPLEX 1; ADAPTOR PROTEIN COMPLEX MU SUBUNITS; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CARRIER PROTEINS; CELL LINE; CELL MEMBRANE; CLATHRIN; ENDOCYTOSIS; ENDOSOMES; EXOCYTOSIS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PROTEIN TRANSPORT; RECEPTOR, IGF TYPE 2; UP-REGULATION;

ANIMALIA;

EID: 0035691925     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Mannose 6-Phosphate/Insulin-like growth factor II receptor mediates internalization and degradation of leukemia inhibitory factor but not signal transduction
2. Serine phosphorylation site of the 46-kDa mannose 6-phosphate receptor is required for transport to the plasma membrane in Madin-Darby canine kidney and mouse fibroblast cells
3. Mutational analysis of the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor. A consensus casein kinase II site followed by 2 leucines near the carboxyl terminus is lysosomal enzymes
4. The Rab5 effector EEA1 is a core component of endosome docking
5. I-cell disease-like phenotype in mice deficient in mannose-6-phosphate receptors
6. γ Subunit of the AP-1 adaptor complex binds clathrin: Implications for cooperative binding in coated vesicle assembly
7. Receptor-mediated endocytosis of low-density lipoprotein in cultured cells
8. Fine structure immunocytochemistry
9. Recognition of sorting signals by clathrin adaptors
10. Phosphorylation of the human 46-kDa mannose 6-phosphate receptor in the cytoplasmic domain at serine 56
11. Mannose 6-phosphate receptors in sorting and transport of lysosomal enzymes
12. Clathrin and adaptors
13. The cytoplasmic tail of the mannose 6-phosphate/insulin-like growth factor-II receptor has two signals for lysosomal enzyme sorting in the Golgi
14. Mannose-6-phosphate/insulin-like growth factor-II receptor is a receptor for retinoic acid
15. Adaptors for clathrin-mediated traffic
16. Differences in the endosomal distributions of the two mannose-6-phosphate receptors
17. A lipid associated with the antiphospholipid syndrome regulates endosome structure and function
18. Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors
19. Recruitment of epidermal growth factor receptors into coated pits requires their activated tyrosine kinase
20. Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds
21. Phosphorylation of the cation-independent mannose-6-phosphate receptor is closely associated with its exit from the trans-Golgi network
22. μ1A adaptin-deficient mice: Lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptors
23. Bi-cycling the furin pathway: From TGN localization to pathogen activation and embryogenesis
24. Mannose 6-phosphate/Insulin-like growth factor II receptor is a death receptor for Granzyme B during cytotoxic T cell-induced apoptosis
25. Mannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interaction
26. μ1B, a novel adaptor medium chain expressed in polarized epithelial cells
27. Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin
28. Clathrin-coated vesicle formation and protein sorting: An integrated process
29. Relations between the intracellular pathways of the receptors for transferrin, asialoglycoprotein, and mannose 6-phosphate in human hepatoma cells
30. A mono phenylalanine-based motif (F790) and a leucine-dependent motif (LI760) mediate internalization of furin
31. Recycling of furin from the plasma membrane. Functional importance of the cytoplasmic tail sorting signals and interaction with the AP-2 adaptor medium chain subunit
32. The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor
33. The rate of internalization of the mannose 6-phosphate/insulin-like growth factor II receptor is enhanced by multivalent ligand binding