Comparative phenotype and immunogenicity of freshly isolated and immortalized rat hepatocytes

Cell Transplantation

Volumn 10, Issue 8, 2001, Pages 739-747

  Kaulek, V ^a   Saas, P ^a   Alexandre, E ^b   Grant, H ^c   Richert, L ^d   Jaeck, D ^b   Tiberghien, P ^a   Wolf, P ^b   Azimzadeh, A ^b  

^a ETABLISSEMENT FRANÇAIS DU SANG   (France)

^b Laboratoire de Chirurgie Experimentale   (France)

^c UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^d UNIVERSITÉ DE FRANCHE COMTÉ   (France)

Author keywords

Allotransplantation; CD8; Freshly isolated hepatocytes; Immortalized hepatocytes; Intercellular adhesion molecule 1; MHC

Indexed keywords

CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; MAJOR HISTOCOMPATIBILITY ANTIGEN; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL IMMORTALIZATION; CELL PROLIFERATION; CELL TRANSPLANTATION; CONTROLLED STUDY; FLOW CYTOMETRY; HEPATOCYTE TRANSPLANTATION; IMMUNOGENICITY; LIVER CELL; MALE; MIXED LYMPHOCYTE CULTURE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0035691237     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/000000001783986242     Document Type: Article

References (38)

1. Cytotoxicity of xenobiotics and expression of glutathione-S-transferases in immortalised rat hepatocyte cell lines
2. Immortalized hepatocytes as in vitro model systems for toxicity testing: The comparative toxicity of menadione in immortalized cells, primary cultures of hepatocytes and HTC hepatoma cells
3. Hepatocyte transplantation
4. Cell subsets responding to purified hepatocytes and evidence of indirect recognition of hepatocyte major histocompatibility complex Class I antigen. I. The role of L3T4 + T cells in the development of allospecific cytotoxicity in hepatocyte sponge matrix allografts
5. Cell subsets responding to purified hepatocytes and evidence of indirect recognition of hepatocyte major histocompatibility complex Class I antigen. II. In vitro generated "memory" cells to Class I+ Class II-hepatocytes
6. Afferent and efferent pathways in T cell responses to MHC Class I+, II- hepatocytes
7. Effect of tumor necrosis factor and intercellular adhesion molecule-1 expression on immunogenicity of murine liver cells in mice
8. Efficacy of anti-intercellular adhesion molecule-1 immunotherapy on immune responses to allogeneic hepatocytes in mice
9. Comparison of in vivo and in vitro immune response to purified hepatocytes
10. Unusual patterns of alloimmunity evoked by allogeneic liver parenchymal cells
11. MHC expression on human hepatocytes before and after isolation
12. Lack of Class II antigen expression on hepatocytes profoundly affects CTL development in vitro and in vivo
13. Collagen substrata for studies on cell behavior
14. Cationic lipid-mediated transfer of the h IL-10 gene prolongs survival of allogeneic hepatocytes in Nagase analbuminemic rats
15. Inbred strains
16. Treatment of Crigler-Najjar syndrome type I with hepatocyte transplantation
17. Hepatocyte transplantation: Prognosis for a clinical future
18. Graft-versus-host reactions in the beige mouse. An investigation of the role of host and donor natural killer cells in the pathogenesis of graft-versus-host disease
19. Expression of early genes of origin-defective mutants of simian virus 40
20. Hepatocyte transplantation back to the future
21. CD4+ Vα 14 natural killer T cells are essential for acceptance of rat islet xenografts in mice
22. Quantitative assay for albumin producing liver cells after simian virus 40 transformation of rat hepatocytes maintained in chemically-defined medium
23. The immunology of experimental liver transplantation in rat
24. Immune modulation of adhesion molecules ICAM-1 (CD54) and LFA-3 (CD58) in human hepatocytic cell lines
25. Expression of liver functions in immortalised rat hepatocyte cell lines
26. The immortalisation of rat hepatocytes by transfection with SV 40 sequences
27. Long-term survival of functional hepatocytes from adult rat in the presence of phenobarbital in primary culture
28. Inflammatory cytokines up-regulate intercellular adhesion molecule-1 expression on primary cultured mouse hepatocytes and T-lymphocyte adhesion
29. Interleukin-2-activated natural killer cells can support hematopoiesis in vitro and promote marrow engraftment in vivo
30. Treatment of surgically induced acute liver failure by transplantation of conditionally immortalized hepatocytes
31. + cells in the liver of mice
32. Proinflammatory cytokines and endotoxin stimulate ICAM-1 gene expression and secretion by normal human hepatocytes
33. Effects of proinflammatory cytokines on cultivated primary human hepatocytes. Fluorometric measurement of intercellular adhesion molecule-1 and human leucocyte antigen-A, -B, -C, and -DR expression
34. Preparation of isolated rat liver cells
35. Hepatocyte transplantation as a bridge to orthotopic liver transplantation in terminal failure
36. Long-term amelioration of bilirubin glucuronidation defect in Gunn rats by transplanting genetically modified immortalized autologous hepatocytes
37. Induction of intercellular adhesion molecule-1 (CD54) on human hepatoma cell line HepG2: Influence of cytokines and hepatitis B virus-DNA transfection
38. Reversible immortalization of mammalian cells mediated by retroviral transfer and site-specific recombination