Hepatitis B virus MHBs antigen is selectively sensitive to glucosidase-mediated processing in the endoplasmic reticulum

DNA and Cell Biology

Volumn 20, Issue 10, 2001, Pages 647-656

  Lu, Xuanyong ^a   Lu, Yefei ^a   Geschwindt, Ryan ^a   Dwek, Raymond A ^b   Block, Timothy M ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; DIMER; ENZYME INHIBITOR; GENE PRODUCT; GLUCOSIDASE; GLYCOPROTEIN; POLYPEPTIDE;

ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME INHIBITION; GENE STRUCTURE; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PROCESSING; VIRAL GENETICS; VIRUS ENVELOPE; VIRUS GENE;

CELL LINE; ENDOPLASMIC RETICULUM; GENES, VIRAL; GLUCOSIDASES; GLYCOSYLATION; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HUMANS; PARTICLE SIZE; PLASMIDS; PROTEIN PROCESSING, POST-TRANSLATIONAL; TRANSFECTION; VIRAL ENVELOPE PROTEINS; VIRAL STRUCTURAL PROTEINS;

HEPATITIS B VIRUS;

EID: 0035689828     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/104454901753340631     Document Type: Article

References (22)

1. Secretion of human hepatitis B virus is inhibited by the imino sugar, N-butyldeoxynojirimycin
2. Antiviral effect of N-butyldeoxynojirimycin against bovine viral diarrhea virus correlates with misfolding of E2 envelope proteins and impairment of their association into E1-E2 heterodimers
3. The role of envelope proteins in hepatitis B virus assembly
4. Functions of the internal pre-S domain of the large surface protein in hepatitis B virus particle morphogenesis
5. Glycobiology: More functions for oligosaccharides
6. Studies on the attachment and penetration of hepatitis B virus
7. Interactions between hepatitis B virus and cell membranes
8. Immunogenecity of S and preS domains in hepatitis virions and HBsAg filaments
9. Evaluation of tetrazolium-based semiautomated colorimetric assay for measurement of human antitumor cytotoxicity
10. How N linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum
11. Hepatitis B surface antigen assembles in a post ER, pre Golgi compartment
12. Evidence that N-linked glycosylation is necessary for hepatitis B virus secretion
13. Aberrant trafficking of hepatitis B virus glycoproteins in cells in which N-glycan processing is inhibited
14. Protease-induced infectivity of human hepatitis B virus for continuous cultures of human liver cells
15. Hepatitis B virus envelope proteins vary drastically in their sensitivity to glycan processing
16. α-glucosidase inhibitors as potential broad based antivral agents
17. Fine mapping and functional characterization of two immunodominant regions from the preS2 sequence of hepatitis B virus
18. Chaperons involved in hepatitis B virus morphogenesis
19. Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA
20. Three envelope protein of hepatitis B virus: Large S, middle S, and major SHBs needed for the formation of Dane particles
21. Relationship between viral DNA synthesis and virion envelopment in hepatitis B virus
22. Role for calnexin and N-linked glycosylation in the assembly and secretion of hepatitis B virus middle envelope protein particles