Effect of ursodeoxycholic acid on prostaglandin metabolism and microsomal membranes in alcoholic fatty liver

Alcohol

Volumn 25, Issue 2, 2001, Pages 99-105

  Lukivskaya, Oxana Ya ^a   Maskevich, Alexandr A ^b   Buko, Vyacheslav U ^a  

^a INSTITUTE OF BIOCHEMISTRY   (Belarus)

^b YANKA KUPALA STATE UNIVERSITY OF GRODNO   (Belarus)

Author keywords

6 Desaturase; Alcohol; Fatty acids; Fatty liver; Microsomal membranes; Prostaglandins; Ursodeoxycholic acid

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; CHOLESTEROL ESTER; FLUORESCENT DYE; GAMMA GLUTAMYLTRANSFERASE; INOSITOL PHOSPHATE; LINOLEOYL COENZYME A DESATURASE; PHOSPHOLIPID DERIVATIVE; PROSTAGLANDIN E2; PROSTAGLANDIN E2 SYNTHASE; SATURATED FATTY ACID; SPHINGOMYELIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID; URSODEOXYCHOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; FATTY ACID METABOLISM; FATTY LIVER; LIPID DIET; LIVER MICROSOME; LIVER PROTECTION; MALE; MEMBRANE STABILIZATION; MICROSOME MEMBRANE; NONHUMAN; PROSTAGLANDIN METABOLISM; RAT; STOMACH INTUBATION; VISCOSITY;

ANIMALS; CELL POLARITY; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CHOLAGOGUES AND CHOLERETICS; DINOPROSTONE; ETHANOL; FATTY ACIDS; FATTY LIVER, ALCOHOLIC; INTRACELLULAR MEMBRANES; LIPID METABOLISM; MALE; MICROSOMES, LIVER; RATS; RATS, WISTAR; URSODEOXYCHOLIC ACID; VISCOSITY;

ANIMALIA;

EID: 0035679490     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-8329(01)00171-9     Document Type: Article

References (42)

1. Role of ethanol-inducible cytochrome P450 (P450IIE1) in catalysing the free radical activation of aliphatic alcohols
2. Colorimetric assay method for free and phosphorilated glyceric acid
3. Chronic administration of ursodeoxycholic and tauroursodeoxycholic acid changes microsomal membrane lipid content and fatty acid compositions in rats
4. Report of the American Institute of Nutrition Ad Hoc Committee on standards for nutritional studies
5. Molecular mechanisms of hepatoprotective action of prostaglandins in alcoholic liver injury
6. Antiradical and antioxidative properties of compounds having the steroid structure
7. Cytochrome P-450 and free radical generation in rat liver microsomes under the influence of prostaglandin E1
8. Role of microsomal ethanol-oxidizing system in regulation of linoleoyl-CoA desaturase activity after long-term ethanol administration
9. Hepatic expression of class I and class II major histocompatibility complex molecules in primary biliary cirrhosis: Effect of ursodeoxycholic acid
10. The effects of chronic ethanol consumption on hepatic mitochondrial energy metabolism
11. Effect of epinephrine on the oxidative desaturation of fatty acids in the rat
12. The effect of the prostaglandin analogue misoprostol on rat liver mitochondria after chronic alcohol feeding
13. A simple method for the isolation and purification of total lipids from animal tissue
14. Lateral diffusion in the hydrophobic region of membranes: Use of pyrene excimers as optical probes
15. Molecular aspects of membrane stabilization by ursodeoxycholate
16. Effects of unsaturated fatty acids on cell membrane functions
17. 3
18. Ursodeoxycholic acid treatment for chronic cholestatic liver disease
19. Ursodeoxycholic acid improves ethinyl estradiol-induced cholestasis in rat
20. 125I-labelled glucagon binding as a metabolic probe
21. Cytoprotection by ursodeoxycholic acid
22. Quantitative relationship between amount of dietary fat and severity of alcoholic fatty liver
23. Alcoholic liver disease: Pathobiological aspects
24. Ursodeoxycholic acid suppresses extent of lipid peroxidation in diseased liver in experimental cholestatic liver disease
25. Ethanol sensitivity and fatty acid composition of chick liver mitochondrial and microsomal membranes
26. Comparison of the peroxidase activity of hemoproteins and cytochrome P-450
27. Prostaglandin E2 and leukotriene B4 synthesis by peripheral leucocytes in alcoholics
28. Alcoholic liver disease
29. Use of reverse transcription-polymerase chain reaction to evaluate in vivo cytokine gene expression in rats fed ethanol for long periods
30. Effect of tauroursodeoxycholic and ursodeoxycholic acid on ethanol-induced cell injuries in the human Hep G2 cell line
31. Role of cytokines in ethanol-induced cytotoxicity in vitro in Hep G2 cells
32. Implication of free radical mechanisms in ethanol-induced cellular injury
33. Ursodeoxycholate alleviates alcoholic fatty liver damage in rats
34. Ursodeoxycholic acid in the treatment of alcoholic liver disease
35. Management of primary billiary cirrhosis resistant to ursodeoxycholic acid therapy
36. Relationship of the acyl-CoA desaturases to certain membrane fatty acids changes induced by ethanol consumption
37. Effect of ursodeoxycholic acid on in vivo and in vitro toxic liver injury in rats
38. Pathogenesis of alcoholic hepatic steatosis
39. Protective effect of prostaglandin E1 against ischemia/reperfusion-induced liver injury: Results of a prospective, randomized study in cirrhotic patients undergoing subsegmentectomy
40. Ursodeoxycholate protects against ethanol-induced liver mitochondrial injury
41. Mechanism of prostaglandin biosynthesis in rabbit kidney medulla. A rate-limiting step and the differential stimulatory actions of L-adrenaline and glutathione
42. Characterization of the reaction of GDP-mannose with dolichol phosphate in liver membranes