The polysialyltransferase ST8Sia II/STX: Posttranslational processing and role of autopolysialylation in the polysialylation of neural cell adhesion molecule

Glycobiology

Volumn 11, Issue 11, 2001, Pages 997-1008

  Close, B E ^a   Wilkinson, J M ^a   Bohrer, T J ^a   Goodwin, C P ^a   Broom, L J ^a   Colley, K J ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

Autopolysialylation; Glycosylation; NCAM; Polysialyltransferase; ST8Sia II

Indexed keywords

ALPHA2,8 POLYSIALYLTRANSFERASE; ASPARAGINE; CELL PROTEIN; ENZYME; NERVE CELL ADHESION MOLECULE; OLIGOSACCHARIDE; POLYSIALIC ACID; SIALYLTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL INTERACTION; CELL STRAIN COS1; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MODIFICATION; IMMUNOBLOTTING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; SIALYLATION;

ANIMALS; ASPARAGINE; BASE SEQUENCE; BINDING SITES; COS CELLS; DNA, COMPLEMENTARY; GLYCOSYLATION; MUTAGENESIS, SITE-DIRECTED; NEURAL CELL ADHESION MOLECULE L1; NEURAL CELL ADHESION MOLECULES; OLIGOSACCHARIDES; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; SIALIC ACIDS; SIALYLTRANSFERASES;

ANIMALIA;

EID: 0035676894     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/11.11.997     Document Type: Article

References (69)

1. NCAM polysialic acid can regulate both cell-cell and cell-substrate interactions
2. Human STX polysialyltransferase forms the embryonic form of the neural cell adhesion molecule
3. Unique disulfide bond structures found in ST8Sia IV polysialyltransferase are required for its activity
4. Differential and cooperative polysialylation of the neural cell adhesion molecules by two polysialyltransferases, PST and STX
5. Expression of neural cell adhesion molecules, NCAMs, and their polysialylated forms, PSA-NCAMs, in the developing rat pituitary gland
6. A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels
7. Minimal structural and glycosylation requirements for ST6Gal I activity and trafficking
8. In vivo autopolysialylation and localization of the polysialyltransferases PST and STX
9. Polysialyltransferase-1 autopolysialylation is not requisite for polysialylation of neural cell adhesion molecule
10. 2-terminal signal anchor with a signal peptide
11. The signal anchor and stem regions of the β-galactoside α2, 6-sialyltransferase may each act to localize the enzyme to the Golgi apparatus
12. Neural cell adhesion molecule: Structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing
13. Expression of NCAM and its polysialylated forms during mdx mouse muscle regeneration and in vitro myogenesis
14. Molecular characterization of eukaryotic polysialyltransferase-1
15. Cell adhesion and the molecular process of morphogenesis
16. Cell adhesion molecules: Implications for a molecular histology
17. Occurrence of α2, 8-linked polysialosyl units in a neural cell adhesion molecule
18. An IgG monoclonal antibody to group B meningococci cross-reacts with developmentally regulated polysialic acid units of glycoproteins in neural and extraneural tissues
19. Polysialyltransferase ST8Sia II (STX) polysialylates all of the major isoforms of NCAM and facilitates neurite outgrowth
20. Possible roles of tumor-associated carbohydrate antigens
21. Polysialylated neural cell adhesion molecule as a marker for differential diagnosis in pediatric tumors
22. NCAM: Structural diversity, function, and regulation of expression
23. Heterogeneous expression of the polysialyltransferases ST8Sia II and ST8Sia IV during postnatal rat brain development
24. Isolation of a novel glycoprotein from the eggs of rainbow trout: Occurrence of disialosyl groups on all carbohydrate chains
25. Expression of the embryonal neural cell adhesion molecule N-CAM in lung carcinoma. Diagnostic usefulness of monoclonal antibody 735 for the distinction between small cell lung cancer and non-small cell lung cancer
26. Cell biology of polysialic acid
27. Identification of polysialic acid-containing glycoprotein in the jelly coat of sea urchin eggs: Occurrence of a novel type of polysialic acid structure
28. Differential biosynthesis of polysialic or disialic acid structure by ST8Sia II and ST8Sia IV
29. Enzymatic activity of a developmentally regulated member of the sialyltransferase family (STX): Evidence for α2, 8-sialyltransferase activity toward Asn-linked oligosaccharides
30. Assembly of asparagine-linked oligosaccharides
31. Polysialic acid synthase (ST8Sia II/STX) mRNA expression in the developing mouse central nervous system
32. Cleavage of structural proteins during assembly of the head of bacteriophage T4
33. Polymerase chain reaction of a developmentally regulated member of the sialyltransferase gene family
34. Extended polysialic acid chains (n > than 55) in glycoproteins from human neuroblastoma cells
35. Two naturally occurring α2, 6-sialyltransferase forms with a single amino acid change in the catalytic domain differ in their catalytic activity and proteolytic processing
36. Unique α2, 8-polysialylated glycoproteins in breast cancer and leukemia cells
37. NCAM and lung cancer
38. Expression of neural cell adhesion molecules (polysialylated form of neural cell adhesion molecule and L1-adhesion molecule) on resected small cell lung cancer specimens: In relation to proliferation state
39. Expression of neural cell adhesion molecule-related sialoglycoprotein in small cell lung cancer and neuroblastoma cell lines H69 and CHP-212
40. Autocatalytic polysialylation of polysialyltransferase-1
41. Polysialic acid: Three-dimensional structure, biosynthesis, and function
42. The impact of N-glycosylation on the functions of polysialyltransferases
43. Expression cloning of a human polysialyltransferase that forms the polysialylated neural cell adhesion molecule present in embryonic brain
44. Protein determinants for specific polysialylation of the neural cell adhesion molecule
45. Carbohydrate antigens in human lung carcinomas
46. Developmental expression of two rat sialyltransferases that modify the neural cell adhesion molecule, N-CAM
47. Escherichia coli K1 capsular polysaccharide associated with neonatal meningitis
48. Polysialic acid units are spatially and temporally expressed in developing postnatal rat kidney
49. Reexpression of poly(sialic acid) units of the neural cell adhesion molecule in Wilms' tumor
50. Presence of the long chain form of polysialic acid of the neural cell adhesion molecule in Wilms' tumor. Identification of a cell adhesion molecule as an oncodevelopmental antigen and implications for tumor histogenesis
51. Differences in the carbohydrate structures of neural cell-adhesion molecules from adult and embryonic brain
52. Polysialic acid and the regulation of cell interactions
53. Polysialic acid in the vertebrate nervous system: A promoter of plasticity in cell-cell interactions
54. Specific alteration of NCAM-mediated cell adhesion by an endoneuraminidase
55. The neural cell adhesion molecule (NCAM) as a regulator of cell-cell interactions
56. Adult and embryonic mouse neural cell adhesion molecules have different binding properties
57. Frequent occurrence of pre-existing α2, 8-linked disialic and oligosialic acids with chain lengths up to 7 sia residues in mammalian brain glycoproteins: Prevalence revealed by highly sensitive chemical and poly-sia antibodies specific for defined chain lengths
58. In vitro and in vivo growth of clonal sublines of human small cell lung carcinoma is modulated by polysialic acid of the neural cell adhesion molecule
59. A human STX confers polysialic acid expression in mammalian cells
60. Retinoic acid-induced changes in polysialyltransferase mRNA expression and NCAM polysialylation in human neuroblastoma cells
61. Control of NCAM polysialylation by the differential expression of polysialyltransferases ST8Sia II and ST8Sia IV
62. Polysialylation: From bacteria to brains
63. Sialobiology and the polysialic acid glycotope: Occurrence, structure, synthesis, and glycopathology
64. Biosynthesis of the polysialic acid capsule in Escherichia coli K1
65. Cardiac expression of polysialylated NCAM in the chicken embryo: Correlation with the ventricular conduction system
66. Molecular defects that cause loss of polysialic acid in the complementation group 2A10
67. Molecular cloning and characterization of a third type of N-glycan α2, 8-sialyltransferases from mouse lung
68. Polysialic acid is associated with sodium channels and the neural cell adhesion molecule N-CAM in adult rat brain