A method for measurement of muscarinic receptor-mediated responses in dissociated single colon longitudinal smooth muscle cells

Journal of Pharmacological and Toxicological Methods

Volumn 45, Issue 3, 2001, Pages 199-205

  Kobayashi, Seiji ^a   Ikeda, Ken ^a   Miyata, Keiji ^a   Yamada, Toshimitsu ^a   Honda, Kazuo ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Ca2+ mobilization; Colon; Cytosensor; Extracellular acidification; Guinea pig; Methods; Muscarinic receptor; Na+ H+ exchanger; Smooth muscle cells

Indexed keywords

4 DIPHENYLACETOXY 1 METHYLPIPERIDINE; AMILORIDE DERIVATIVE; ATROPINE; CARBACHOL; COLLAGENASE; HYALURONIDASE; METHOCTRAMINE; MUSCARINIC AGENT; MUSCARINIC M2 RECEPTOR ANTAGONIST; MUSCARINIC M3 RECEPTOR ANTAGONIST; MUSCARINIC RECEPTOR BLOCKING AGENT; PAPAIN; PROTON; SODIUM ION;

ACIDIFICATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL ISOLATION; CONTROLLED STUDY; DRUG POTENCY; FLUOROMETRY; GUINEA PIG; INTESTINE CELL; MALE; NONHUMAN; SMOOTH MUSCLE FIBER;

AMILORIDE; ANIMALS; ATROPINE; CALCIUM; CARBACHOL; CELL SEPARATION; CHOLINERGIC AGONISTS; COLON; DIAMINES; DOSE-RESPONSE RELATIONSHIP, DRUG; FURA-2; GUINEA PIGS; MALE; MUSCLE, SMOOTH; PIPERIDINES; RECEPTORS, MUSCARINIC;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0035671283     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8719(01)00149-6     Document Type: Article

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