Induction of multi-epitope-specific antibodies against HIV-1 by multi-epitope-vaccines

Chinese Science Bulletin

Volumn 46, Issue 22, 2001, Pages 1859-1864

  Ding, J ^a   He, F ^a   Lu, Y ^a   Xiao, Y ^a   Chen, Y ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

HIV 1; Multi epitope vaccine; Neutralizing epitope

Indexed keywords

EPITOPE; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NEUTRALIZING ANTIBODY;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE RESPONSE; NONHUMAN; RABBIT; RHESUS MONKEY; SIGNAL TRANSDUCTION; VIRUS MUTATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA; ORYCTOLAGUS CUNICULUS;

EID: 0035670520     PISSN: 10016538     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02901157     Document Type: Article

References (21)

1. Immunological and virological analyses of persons infected by human-immunodeficiency-virus type-1 while participating in trials of recombinant gp120 subunit vaccines
2. A conserved neutralizing epitope on gp41 of human immunodeficiency virus type I
3. HIV-1 neutralizing antibodies: How full is the bottle?
4. Epitope-vaccine: A new strategy against HIV-1
5. Human immunodeficiency yirus type 1 neutralizing antibodies accelerate clearance of cell-free virions from blood plasma
6. Neutralizing antibodies in sera from macaques infected with chimeric siman-human immunodeficiency virus containing the envelope glycoproteins of either a laboratory-adapted variant or a primary isolate of human immunodeficiency type
7. Association of antibody reactivity to ELDKWA, a glycoprotein 41 neutralization epitope, with disease progression in children perinatally infected with HIV type 1
8. Structure and polymorphism of HIV-1 third variable loops
9. Prevention of HIV-1 infection in chimpanzees by gp120 V3 domain-specific monoclonal antibody
10. A common epitope on gp41, IFN-α and IFN-β induces protective activity
11. Role of immune responses against the envelope and the core antigens of simian immunodeficiency virus SIV in protection against homologous cloned and uncloned virus challenge in Macaques
12. Passively transferred antibodies directed against conserved regions of SIV envelope protect macaques from SIV infection
13. Core structure of gp41 from the HIV envelope glycoprotein
14. Fusion-competent vaccines: Broad neutralization of primary isolates of HIV
15. Immunogenicity of the GPGRAFY-epitope on synthetic peptides
16. HIV epitope-peptides in aluminum adjuvant induced high levels of epitope-specific antibodies
17. Induction of high levels of epitope-specific antibodies by epitope/peptide candidate vaccines against human immunodeficiency virus type I (HIV-1)
18. Multiepitope vaccines intensively increased levels of antibodies recognizing three neutralizing epitopes of human immunodeficiency virus-1 envelope protein
19. A strategy for rational design of fully synthetic glycopeptide conjugate vaccines
20. Immunogenicity of neutralizing-epitopes on multiple-epitope vaccines against HIV-1
21. Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies