Dysregulated L-selectin expression on lymphocytes in patients with chronic venous insufficiency

Clinical Hemorheology and Microcirculation

Volumn 25, Issue 1, 2001, Pages 21-30

  Jünger, Michael ^a   Friedrich, Björn ^b   Hahn, Jens ^c   Klyscz, Thomas ^a,b   Müller, Claudia A ^c   Schmid Schönbein, Geert W ^a  

^a UNIVERSITY MEDICINE GREIFSWALD   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Leukocyte adhesion molecules; Varicose ulcer immunology; Varicose ulcer pathophysiology; Venous leg ulcer

Indexed keywords

BETA1 INTEGRIN; CD11B ANTIGEN; CD18 ANTIGEN; GLYCOPROTEIN P 15095; L SELECTIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CHRONIC VEIN INSUFFICIENCY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; LEG ULCER; LYMPHOCYTE; MALE; ORTHOSTATIC HYPOTENSION; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; VENOUS STASIS;

ADULT; AGED; CASE-CONTROL STUDIES; CELL ADHESION MOLECULES; CHRONIC DISEASE; FLOW CYTOMETRY; HUMANS; L-SELECTIN; LEG ULCER; LYMPHOCYTES; MIDDLE AGED; NEUTROPHILS; STRESS; VENOUS INSUFFICIENCY;

EID: 0035666498     PISSN: 13860291     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. C.J. Barnstable, W.F. Bodmer, G. Brown, G. Galfre, C. Milstein, A.F. Williams and A. Ziegler, Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens - new tools for genetic analysis, Cell 14 (1978), 9-20.
2. G. Borland, G. Murphy and A. Ager, Tissue inhibitor of metalloproteinases-3 inhibits shedding of L-selectin from leukocytes, J. Biol. Chem. 274 (1999), 2810-2815.
3. C.M. Butler and P.D. Coleridge-Smith, Microcirculatory aspects of venous ulcération, J. Dermatol. Surg. Oncol. 20 (1994), 474-480.
4. T.M. Carlos and J.M. Harlan, Leukocyte-endothelial adhesion molecules, Blood 84 (1994), 2068-2101.
5. C. Dong, G.W. Schmid-Schönbein and R. Skalak, Rheological behaviour of leukocytes, in: Proceedings of the 1985 Biomechanics Symposium, D. Butler, T.K. Hung and R.E. Mates, eds. Joint ASCE/ASME Mechanics Conference, Albuquerque, NM, pp. 163-166.
6. G. Endemann, Y. Abe, C.M. Brynat, Y. Feng, C.W. Smith and D.Y. Liu, Novel and-inflammatory compounds induce shedding of L-selectin and block primary capture of neutrophils under flow conditions, J. Immunol. 158 (1997), 4879-4885.
7. B. Gu, L.J. Bendall and J.S. Wiley, Adenosine triphosphate-induced shedding of CD23 and L-selectin (CD62L) from lymphocytes is mediated by the same receptor but different metalloproteases, Blood 92 ( 1998), 946-951.
8. M. Jünger, M. Hahn, T. Klyscz and A. Steins, Role of microangiopathy in the development of venous leg ulcers, in: Micmcirculation in Chronic Venous Insufficiency, K. Messner, ed., Prog. Appl. Microcirc., Vol. 23, Basel, Karger, 1999, pp. 180-193.
9. W.M. Kuebler, X. Ying, B. Singh, A.C. Issekutz and J. Bhattacharya, Pressure is proinflammatory in lung venular capillaries,! Clin. Invest. 104 (1999), 495-502.
10. K. Ley, D.C. Bullard, M.L. Arbones, R. Bosse, D. Vestweber, T.F. Tedder and A.L. Beaudet, Sequential contribution of L- and P-selectin to leukocyte rolling in vivo, J. Exp. Med. 181 (1995), 669-675.
11. K. Ley, Molecular mechanisms of leukocyte rolling and adhesion to microvascular endothelium, Eur. Heart J. 14 (1993), 68-73.
12. F. Moazzam, F.A. DeLano, B.W. Zweifach and G.W. Schmid-Schönbein, The leukocyte response to fluid stress, Proc. Nat. Acad. Sei. USA 94 (1997), 5338-5343.
13. D.A. Moore, D. Henderson and B.G. Gazzard, Neutrophil adhesion molecules in HIV disease, Clin. Exp. Immunol. 114 (1998), 73-77.
14. J. Panes, M. Perry and D.N. Granger, Leukocyte-endothelial cell adhesion: avenues for therapeutic intervention, Br. J . Pharmacol. 126 (1999), 537-550.
15. S.B. Rizoli, A. Kapus, J. Fan, Y.H. Li, J.C. Marshall and O.D. Rotstein, Immunmodulatory effects of hypertonic resuscitation on the development of lung inflammation following hemorrhagic shock, J. Immunol. 161 (1998), 6288-6296.
16. M. Saharay, D.A. Shields, J.B. Porter, J.H. Scurr and P.D. Coleridge-Smith, Leukocyte activity in the microcirculation of the leg in patients with chronic venous disease, J. Vase. Surg. 25 (1997), 265-273.
17. G.W. Schmid-Schönbein, S. Usami, R. Skalak and S. Chien, The interaction of leukocytes and erythrocytes in capillary and postcapillary vessels, Microvasc. Res. 19 (1980), 45-70.
18. D.A. Shields, M. Saharay, J.H. Scurr and J.B. Porter, L-selectin as a marker of adhesion in experimental venous hypertension, Br. J. Surg. 83 (1996), 683.
19. T.F. Tedder, W. Lusinskas and O.S. Kansas, Regulation of leukocyte migration by L-selectin: Mechanisms, domains and ligands, Behring Inst. Mitt. 92 (1993), 165-177,
20. S.J. Weiss, Tissue destruction by neutrophils, N. Engl. J. Med. 320 (1989), 365-376.
21. C. Zouki, M. Beauchamp, C. Baron and J.G. Filep, Prevention of in vitro neutrophil adhesion to endothelial cells through shedding of L-selectin by C-reactive protein and peptides derived from C-reactive protein, J. Clin. Invest. 100 (1997), 522-529.