Creative catalysis: Pieces of the RNA world jigsaw

Trends in Biochemical Sciences

Volumn 26, Issue 12, 2001, Pages 699-701

  Murray, Jeremy M ^a   Doudna, Jennifer A ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; RIBOZYME; RNA;

ACYLATION; CATALYSIS; ENZYME SYNTHESIS; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SHORT SURVEY; TETRAHYMENA;

PROTOZOA; TETRAHYMENA;

EID: 0035663818     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(01)02019-9     Document Type: Review

References (19)

1. In vitro splicing of the ribosomal RNA precursor of Tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence
2. Excised group II introns in yeast mitochondria are lariats and can be formed by self-splicing in vitro
3. The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
4. The RNA world
5. General acid-base catalysis in the mechanism of a hepatitis delta virus ribozyme
6. Structural determinants of enzymatic processivity
7. Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site
8. Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism
9. Crystal structure of a hepatitis delta virus ribozyme
10. Crystal structure of a hairpin ribozyme-inhibitor complex with implications for catalysis
11. In situ probing of adenine protonation in RNA by C-13 NMR
12. RNAs with dual specificity and dual RNAs with similar specificity
13. a in the ribosomal peptidyl transferase center
14. Adenine protonation in domain B of the hairpin ribozyme
15. Direct pK(a) measurement of the active-site cytosine in a genomic hepatitis delta virus ribozyme
16. In vitro selection of functional nucleic acids
17. RNA-catalyzed amino acid activation
18. Specific, rapid synthesis of Phe-RNA by RNA
19. In vitro selection of nucleoprotein enzymes