Localization of blood coagulation factors in situ in pancreatic carcinoma

Thrombosis and Haemostasis

Volumn 86, Issue 6, 2001, Pages 1416-1420

  Wojtukiewicz, M Z ^a   Rucinska, M ^a   Zacharski, L R ^a   Kozlowski, L ^a   Zimnoch, L ^a   Piotrowski, Z ^a   Kudryk, B J ^a   Kisiel, W ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Blood coagulation; Fibrin; Pancreatic cancer

Indexed keywords

BLOOD CLOTTING FACTOR; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 12; BLOOD CLOTTING FACTOR 13A; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 8C; BLOOD CLOTTING FACTOR 9; FIBRIN; FIBRINOGEN; PLASMIN; PLASMINOGEN ACTIVATOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLASMINOGEN ACTIVATOR INHIBITOR 2; PLASMINOGEN ACTIVATOR INHIBITOR 3; PROTHROMBIN; THROMBOPLASTIN; TISSUE FACTOR PATHWAY INHIBITOR;

ADULT; ARTICLE; BLOOD CLOTTING; CANCER GROWTH; CANCER INHIBITION; CANCER SURGERY; CARCINOMA IN SITU; CELL ACTIVATION; CLINICAL ARTICLE; CONTROLLED STUDY; EXTRAVASCULAR SPACE; FEMALE; FIBRINOLYSIS; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; PANCREAS ADENOCARCINOMA; PANCREAS CARCINOMA; PANCREAS ISLET CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REGULATORY MECHANISM; STAINING; STROMA; TISSUE SECTION; TUMOR CELL; VASCULAR ENDOTHELIUM;

EID: 0035655930     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1616744     Document Type: Article

References (44)

1. Hemostatic alterations in cancer patients
2. Hemostasis and cancer
3. Cancer and thrombosis: From plegmasia alba dolens to transgenic mice
4. Thromboembolism in cancer
5. Phlegmasia alba dolens
6. Observations on the developmental patterns and the consequences of pancreatic exocrine adenocarcinoma. Findings of 154 autopsies
7. Carcinoma and venous thrombosis: The frequency of association of carcinoma in the body or tail of the pancreas with multiple venous thrombosis
8. Coagulation inhibition and activation in pancreatic cancer
9. The risk of a diagnosis of cancer after primary deep venous thrombosis or pulmonary embolism
10. Procoagulant activity in cancer cells is dependent on tissue factor expression
11. Pathways of coagulation/fibrinolysis activation in malignancy
12. Tissue factor in cancer angiogenesis and metastasis
13. The AmeX method. A simplified technique of tissue processing and paraffin embedding with improved preservation of antigens for immunostaining
14. Fibrinogen-fibrin transformation in situ in renal cell carcinoma
15. Malignant melanoma. Interaction with coagulation and fibrinolysis pathways in situ
16. Monoclonal antibodies with ability to distinguish between NH2-terminal fragments derived from fibrinogen and fibrin
17. 2-terminal region of fibrin
18. Monoclonal antibodies as probes for fibrin(ogen) proteolysis
19. Clotting factors in tumor tissue: Implications for cancer therapy
20. Abnormal regulationn of coagulation/fibrinolysis in small cell carcinoma of the lung
21. Tumor cell procoagulant and urokinase expression in carcinoma of the ovary
22. Distribution of tissue factor pathway inhibitor in normal and malignant human tissues
23. Pancreatic carcinoma
24. Expression of prothrombin fragment 1+2 in cancer tissue as an indicator of local activation of blood coagulation
25. The present status of tissue factor pathway inhibitor
26. Release of extrinsic pathway inhibitor after heparin injection: Increased response in cancer patients
27. A characterization of the coagulant and fibrinolytic profile of human pancreatic carcinoma cells
28. Peaks in plasma plasminogen activator inhibitor-1 concentration may explain thrombotic events in cases of pancreatic carcinoma
29. Expression of plasminogen activators and their inhibitors in human pancreatic carcinoma: Immunohistochemical study
30. Extrinsic-pathway activation in cancer with high factor VIIa and tissue factor
31. Identification of tissue factor in two human pancreatic cancer cell lines
32. Tissue factor expression correlates with histological grade in human pancreatic cancer
33. The role of fibrin in tumor metastasis
34. Thrombin increases the metastatic potential of tumor cells
35. Tumor cell-induced platelet aggregation in vitro by human pancreatic cancer cell lines
36. Clinical implications of tumor-associated neovascularization and current antiangiogenic strategies for the treatment of malignancies of pancreas
37. Thrombin enhances tumor cell adhesive and metastatic properties via increased ∂11bβ3 expression on the cell surface
38. Fibrin deposition in autochthonous Syrian hamster pancreatic adenocarcinomas induced by the chemical carcinogen N-nitroso-bis (2-oxopropyl) amine
39. Inhibition of hepatic metastasis from a human pancreatic adenocarcinoma (RWP-2) in the nude mouse by prostacyclin, forskolin, and ketoconazole
40. Chemotherapy for carcinoma of the pancreas
41. Complete clinical remission in a patient with advanced pancreatic cancer using mitomycin C-based chemotherapy. The role of adjuvant heparin
42. Heparin and cancer
43. The effect of heparin on the regulation of factor VIIa-tissue factor activity by tissue factor pathway inhibitor
44. The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is over-expressed in human pancreatic cancer