Role of IFN-γ in bacterial containment in a model of intra-abdominal sepsis

Shock

Volumn 16, Issue 6, 2001, Pages 425-429

  Qiu, Gang ^a   Wang, Congli ^a   Smith, Rodman ^a   Harrison, Kathryn ^a   Yin, Kingsley ^a  

^a UMDNJ School of Osteopathic Medicine   (United States)

Author keywords

Bacteria load; Interferon gamma; Rat; Sepsis

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; MONOCYTE CHEMOTACTIC PROTEIN 1;

ADHESION; ANIMAL; ARTICLE; CECUM DISEASE; DISEASE MODEL; IMMUNOLOGY; MALE; METABOLISM; MICROBIOLOGY; PATHOLOGY; PERITONEAL CAVITY; RAT; RAT STRAIN; SEPSIS;

ADHESIONS; ANIMAL; CECAL DISEASES; DISEASE MODELS, ANIMAL; INTERFERON TYPE II; INTERLEUKIN-12; MALE; MONOCYTE CHEMOATTRACTANT PROTEIN-1; PERITONEAL CAVITY; RATS; RATS, SPRAGUE-DAWLEY; SEPSIS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0035651508     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-200116060-00004     Document Type: Article

References (30)

1. Young HA, Hardy KJ: Interferon-γ: producer cells, activation stimuli, and molecular genetic regulation. Pharmacol Ther 45:137-151, 1990.
2. Keller R, Joller P, Keist R, Binz H, van der Meide PH: Modulation of major histocompatibility complex (MHC) expression by interferons and microbial agents. Scand J Immunol 28:113-121, 1988.
3. Brunda M: Interleukin-12. J Leukocyte Biol 55:280-288, 1994.
4. O'Suilleabhain C, O'Sullivan ST, Kelly JL, Lederer J, Mannick JA, Rodrick ML: Interleukin-12 treatment restores normal resistance to bacterial challenge after burn injury. Surgery 120:290-292, 1996.
5. Hershman MJ, Polk HC, Pietsch JD, Kuftinec D, Sonnenfeld G: Modulation of Klebsiella pneumoniae infection of mice by gamma interferon. Clin Exp Immunol 72(3):406-409, 1988.
6. Doherty GM, Lange JR, Langstein HN, Alexander HR, Buresh CM, Norton JA: Evidence for IFN-γ as a mediator of the lethality of endotoxin and tumor necrosis factor. J. Immunol 149:1666-1670, 1992.
7. Heinzel FP: The role of IFN-gamma in the pathology of experimental endotoxemia. J Immunol 145:2920-2924, 1990.
8. Car BD, Eng VM, Schynder B, Ozmen L, Huang S, Gallay P, Hemann D, Aguet M, Ryffel B: Interferon-gamma receptor deficient mice are resistant to endotoxic shock. J Exp Med 179:1437-1444, 1994.
9. Miles RH, Paxton TP, Dries DJ, Gamelli RL: Interferon-gamma increases mortality following cecal ligation and puncture. J Trauma 36(5):607-661, 1994.
10. Hogaboam CM, Steinhauser ML, Schock H, Lukacs N, Strieter RM, Standiford T, Kunkel SL: Therapeutic effects of nitric oxide inhibition during experimental fecal peritonitis: role of Interleukin-10 and Monocyte Chemoattractant Protein 1. Infection Immunity 66(2):650-655, 1998.
11. 4. J Immunol 163:6148-6154, 1999.
12. Chaudry IH, Wichterman KA, Baue AE: Effect of sepsis on tissue adenine nucleotide levels. Surgery 85:205-211, 1979.
13. Abe M, Goya T, Mitsuyama T, Torisu M, Furukawa T: Evaluation of the effects of steroids on experimental septic lung injury. Prostaglandins Leukotrienes Essential Fatty Acids 54(2):123-128, 1996.
14. Weiss YG, Bouwman A, Gehan B, Schears G, Raj N, Deutschman CS: Cecal ligation and double puncture impairs heat shock protein 70(HSP-70) expression in the lungs of rats. Shock 13(1):19-23, 2000.
15. Yin K, Wilmanski J, Wang C, Qiu G, Tahamont M: Lung compartmentalization of inflammatory cells in sepsis. Inflammation 24(6):547-557, 2000.
16. Ayala A, O'Neill PJ, Uebele SA, Herdon CD, Chaudry IH: Mechanism of splenic immunosuppression during sepsis: key role of Kupffer cell mediators. J Trauma 42:882-888, 1997.
17. Zantl N, Uebe A, Neumann B, Wagner H, Siewert J-R, Holzmann B, Heidecke C-D, Pfeffer K: Essential role of gamma interferon in survival of colon ascendens stent peritonitis, a novel murine model of abdominal sepsis. Infection Immunity 66(5):2300-2309, 1998.
18. Yin K, Hock CE, Lai P-S, Ross JT, Yue G: Role of interferon-gamma in lung inflammation following cecal ligation and puncture in rats. Shock 12(3):215-221, 1999.
19. Menzies D, Ellis H: Intestinal obstructions from adhesions-how big is the problem? Ann Rev Coll Surg Engl 72:60-63, 1990.
20. Milligan DW, Raftery AT: Observations on the pathogenesis of peritoneal adhesions: a light and electron microscopical study. Br J Surg 61(4):274-280, 1974.
21. Kitching AR, Holdsworth SR, Tipping PG: IFN-gamma mediates crescent formation and cell-mediated immune injury in murine glomerulonephritis. J Am Soc Nephrol 10(4):752-759, 1999.
22. Musial J, Gluszko P, Undas A, Mahdi F, Kang S, Szczeklik A, Schmaier AH: Gamma interferon administration to patients with atopic dermatitis inhibits fibrinolysis and elevates C1 inhibitor. Thromb Res 89(6):253-261, 1998.
23. Salgado A, Boveda JL, Monasterio J, Segura RM, Mourelle M, Gomez-Jimenez J, Peracaula R: Inflammatory mediators and their influence on hemostasis. Haemostasis 24(2):132-138, 1994.
24. Gurujeyalakshmi G, Giri SN: Molecular mechanisms of antifibrotic effect of interferon-γ in bleomycin-mouse model of lung fibrosis: down-regulation of TGF-β and procollagen I and III gene expression. Exp Lung Res 21(5):791-794, 1995.
25. Miles RH, Paxton TP, Zacheis D, Dries DJ, Gamelli RL: Systemic administration of interferon-γ impairs wound healing. J Surg Res 56(3):288-294, 1994.
26. Angele MK, Knoferl MW, Ayala A, Albina JE, Cioffi WG, Bland KI, Chaudry IH: Trauma-hemorrhage delays wound healing potentially by increasing proinflammatory cytokines at the wound site. Surgery 126(2):279-285, 1999.
27. Ghellai AM, Stucchi AE, Chegini N, Ma C, Andry CD, Kaseta JM, Burns JW, Skinner KC, Becker JM: Role of transforming growth factor beta-1 in peritonitis-induced adhesions. J Gastrointest Surg 4:316-323, 2000.
28. Trinchieri G: Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Ann Rev Immunol 13:251-276, 1995.
29. Steinhauser ML, Hogaboam CM, Lukacs NW, Strieter RM, Kunkel SL: Multiple roles for IL-12 in a model of acute septic peritonitis. J Immunol 162:5437-5443, 1999.
30. Mulligan MS, Warner RL, Foreback JL, Shanley TP, Ward PA: Protective effects of IL-4, IL-10, IL-12 and IL-13 in IgG immune complex-induced lung injury: role of endogenous 11-12. J Immunol 159:3483-3489, 1997.