Protection of retinal ganglion cells from ischemia-reperfusion injury by electrically applied Hsp27

Investigative Ophthalmology and Visual Science

Volumn 42, Issue 13, 2001, Pages 3283-3286

  Yokoyama, Akiko ^a   Oshitari, Toshiyuki ^a   Negishi, Hisanari ^a   Dezawa, Mari ^b   Mizota, Atsushi ^a   Adachi Usami, Emiko ^a  

^a CHIBA UNIVERSITY   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH RELATED PROTEIN P25; GROWTH-RELATED PROTEIN P25; NEUROPROTECTIVE AGENT; TUMOR PROTEIN;

ANIMAL; APOPTOSIS; ARTICLE; DRUG EFFECT; ELECTROPORATION; ISCHEMIA; MALE; PHYSIOLOGY; RAT; RAT STRAIN; REPERFUSION INJURY; RETINA BLOOD VESSEL; RETINA GANGLION CELL;

ANIMAL; APOPTOSIS; ELECTROPORATION; ISCHEMIA; MALE; NEOPLASM PROTEINS; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; REPERFUSION INJURY; RETINAL GANGLION CELLS; RETINAL VESSELS; SUPPORT, NON-U.S. GOV'T;

EID: 0035650544     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Caprioli J, Kitano S, Morgan JE. Hyperthermia and hypoxia increase tolerance of retinal ganglion cells to anoxia and excitotoxicity. Invest Ophthalmol Vis Sci. 1996;37:2376-2381.
2. Yang YL, Lu KT, Tsay HJ, Lin CH, Lin MT. Heat shock protein expression protects against death following exposure to heat-stroke in rats. Neurosci Lett. 1998;252:9-12.
3. Sharp FR, Massa SM, Swanson RA. Heat-shock protein protection. Trends Neurosci. 1999;22:97-99.
4. Yenari MA, Fink SL, Sun GH, et al. Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy. Ann Neurol. 1998;44:584-591.
5. Berbe MF, Tytell M, Gower DJ, Welch WJ. Hyperthermia protects against light damage in the rat retina. Science. 1988;241:1817-1820.
6. Wagstaff MJD, Collaço-Moraes Y, Smith J, Belleroche JS, Coffin RS, Latchman DS. Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector. J Biol Chem. 1999;274:5061-5069.
7. Dezawa M, Takano M, Negishi H, Mo X, Oshitari T, Sawada H. Gene transfer into retinal ganglion cells by in vivo electroporation: a new approach. Micron. 2002;33:1-6.
8. Vidal-Sanz M, Villegas-Perez MP, Bray GM, Aguayo AJ. Persistent retrograde labeling of adult rat retinal ganglion cells with the carbocyanine dye diI. Exp Neurol. 1988;102:92-101.
9. Hightower L, Guidon PT. Selective release from cultured mammalian cells of heat shock (stress) proteins that resemble glia axon transfer proteins. J Cell Physiol. 1989;138:257-266.
10. Grossfeld RM: Axon-glia exchange of macromolecules. Ann New York Acad Sci. 1991;633:318-330.
11. Guzhova IV, Arnholdt ACV, Darieva ZA, et al. Effects of exogenous stress protein 70 on the functional properties of human promonocytes through binding to cell surface and internalization. Cell Stress Chaperones. 1998;3:67-77.
12. Welch WJ, Suhan JP. Morphological study of the mammalian stress response: characterization of changes in cytoplasmic organelles, cytoskeleton, and nucleoli and appearance of intranuclear actin filaments in rat fibroblasts after heat-shock treatment. J Cell Biol. 1985; 101:1198-1211.
13. Lavoie JN, Lambert H, Hickey E, Weber LA, Landry J. Modulation of cellular thermoresistance and actin filament stability accom-panics phosphorylation-induced changes in the oligomeric structure of heat shock protein 27. Mol Cell Biol. 1995;15:505-516.
14. Cuesta R, Laroia G, Schneider J. Chaperon Hsp27 inhibits translation during heat shock by binding elF4G and facilitating dissociation of cap-initiation complexes. Genes Dev. 2000;14: 1460-1470.
15. Conroy SE, Sasieni PD, Amin V, et al. Antibodies to heat-shock protein 27 are associated with improved survival in patients with breast cancer. Br J Cancer. 1998;77:1875-1879.
16. Jäättelä M. Escaping cell death: survival proteins in cancer. Exp Cell Res. 1999;248:30-43.
17. Tezel G, Seigel GM, Bax MB. Autoantibodies to small heat shock proteins in glaucoma. Invest Ophthalmol Vis Sci. 1998;39:2277-2287.
18. Tezel G, Wax MB. Inhibition of caspase activity in retinal ganglion cell apoptosis induced by various stimuli in vitro. Invest Ophthalmol Vis Sci. 1999;40:2660-2667.
19. Tezel G, Wax MB. The mechanism of hsp27 antibody-mediated apoptosis in retinal neuronal cells. J Neurosci. 2000;10:3552-3562.