Multivariate Data Analysis of Fluorescence Signals from Biological Aerosols

Field Analytical Chemistry and Technology

Volumn 5, Issue 4, 2001, Pages 171-176

  Tjärnhage, Torbjörn ^a   Strömqvist, Marianne ^a   Olofsson, Göran ^a   Squirrell, David ^b   Burke, James ^b   Ho, Jim ^c   Spence, Mel ^c  

^a SWEDISH DEFENCE RESEARCH AGENCY   (Sweden)

^b DEFENCE SCIENCE AND TECHNOLOGY LABORATORY   (United Kingdom)

^c Def Res Estab Suffield Box 4000   (Canada)

Author keywords

Detection; Fluorescence of biological aerosols; Identification; Principal component analysis (PCA)

Indexed keywords

EID: 0035600548     PISSN: 1086900X     EISSN: None     Source Type: Journal    
DOI: 10.1002/fact.1018     Document Type: Article

References (17)

1. Walt DR, Franz DR. Biological warfare detection. Anal Chem 2000; 72:738A-746A.
2. Mayo MW, Hill SC. Fluorescence spectra of bacteria, pollens and naturally occuring background. 3rd Workshop for Stand-off Detection for C and B Defence, VA, USA 105-112, Oct. 1994.
3. Cheng G, Nachman P, Pinnick RG, Hill SG, Chang RK. Conditional-firing aerosol-fluorescence spectrum analyzer for individual airborne particles with pulsed 266-nm laser excitation. Opt Lett 1996; 21:6.
4. Pan Y-L, Holler S, Chang RK, Hill SC, Pinnick RG, Niles S, Bottiger JR, Bronk BV. Real-time detection and characterization of individual flowing airborne biological particles: Fluorescence spectra and elastic scattering measurements. Proc SPIE-Int Soc Opt Eng 1999;3855:117-125.
5. Hairston PP, Ho J, Quant R. Design of and instrument for real-time detection of bioaerosols using simultaneous measurements of particle aerodynamic size and intrisic fluorescence. J Aerosol Sci 1997;28:471-482.
6. Pinnick RG, Hill SC, Nachman P, Videen G, Chen G, Chang RK. Aerosol fluorescence spectrum analyzer for rapid measurement of single micrometer-sized airborne biological particles. Aerosol Sci Technol 1998;28:95-104.
7. Hill SC, Pinninck RG, Niles S, Pan Y-L, Holler S, Chang RK, Bottiger J, Chen BT, Orr C-S, Feather G. Real-time measurements of fluorescence spectra from single airborne biological particles. Field Anal Chem Technol 1999;3:221-239.
8. Yee E, Ho J. Neural network recognition and classification of aerosol particle distributions measured with two-spot laser velocimeter. Appl Opt 1990;29:2929-2938.
9. Rosen DL, Gillespie JB. Fluorescence lidar detection with shot noice and sky radiance. Appl Opt 1992;31:4214-4223.
10. Jackson JE. A User's Guide to Principal Components. New York: John Wiley: 1991. (ISBN 0-471-62267-2).
11. Wold S, Albano C, Dunn WJ, Edlund U, Esbensen K, Geladi P, Hellberg S, Johansson E, Lindberg W, Sjöström M. Multivariate data analysis in chemistry. In: Kowalski BR, editer. Chemometrics: Mathematics and Statistics in Chemistry. Dordrecht, Holland: D. Riedel Publishing Company; 1984.
12. Ho J, Spence M. Biochemical detector program field test of agent detection systems (U). Defense Research Establishment Suffield Field Trial Procedure No 288. 1996.
13. Andersen DO, Mohr AJ. Abbreviated test plan for outdoor field trial (JFT III) of prototype biological detection components and systems. DPG Document No DPG-TP-96-041, JPO for Biological Defense. 5201 Leesburg pike, Skyline #3, Suite 1200, Falls Church, VA 22041-3203, 1996.
14. Andersson PO. Fluorescensstudie av mikroorganismer (Study on the fluorescence of microorganisms) FOI, SE-901 82 Umeå, Sweden, FOA-R-99-01177-862-SE, Scientific report in Swedish, 1999.
15. Wold S. Cross-validation estimation of the number of components in factor and principal components models. Technometrics, 1978;20: 397-405.
16. Eriksson L, Johansson E, Kettaneh-Wold N, Wold S. Introduction to Multi-and Megavariate Data Analysis using Projection Methods (PCA and PLS) Ed. June 21, 1999, Umetrics AB, Umeå, Sweden.
17. Höskuldsson A. Prediction Methods in Science and Technology. Copenhagen: Thor Publishing; 1996.