Escape from tolerance of organic nitrate by induction of cytochrome P450

Free Radical Biology and Medicine

Volumn 31, Issue 11, 2001, Pages 1498-1508

  Minamiyama, Yukiko ^a   Imaoka, Susumu ^a   Takemura, Shigekazu ^a   Okada, Shigeru ^b   Inoue, Masayasu ^a   Funae, Yoshihiko ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Blood vessels; CYP isoforms; Free radicals; Nitric oxide; Tolerance; Vasodilation

Indexed keywords

ACETONE; CYTOCHROME P450; GLYCERYL TRINITRATE; NITRIC OXIDE; ORGANIC NITRATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; BLOOD LEVEL; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME PURIFICATION; HYPOTENSION; ISCHEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; URINE LEVEL;

ANIMALS; BLOOD PRESSURE; BLOTTING, WESTERN; COUMARINS; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; DRUG TOLERANCE; ENZYME INDUCTION; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HYDRAZINES; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1; ISOENZYMES; ISOSORBIDE DINITRATE; KINETICS; MALE; MYOCARDIUM; NITRATES; NITRIC OXIDE; NITRIC OXIDE DONORS; NITRITES; NITROGLYCERIN; NITROPRUSSIDE; RATS; RATS, WISTAR;

EID: 0035578250     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00733-X     Document Type: Article

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