메뉴 건너뛰기




Volumn 81, Issue 1 A, 1998, Pages

Thiols and nitrates: Reevaluation of the thiol depletion theory of nitrate tolerance

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLYCERYL TRINITRATE; NITRATE; NITRIC OXIDE; THIOL;

EID: 0031893310     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(97)00994-6     Document Type: Conference Paper
Times cited : (15)

References (86)
  • 1
    • 0020341736 scopus 로고
    • Oral isosorbide dinitrate in angina pectoris: comparison of duration of action and dose-response relation during acute and sustained therapy
    • U Thadani HL Fung AC Drake JO Parker Oral isosorbide dinitrate in angina pectoris comparison of duration of action and dose-response relation during acute and sustained therapy Am J Cardiol 49 1982 411 419
    • (1982) Am J Cardiol , vol.49 , pp. 411-419
    • Thadani, U1    Fung, HL2    Drake, AC3    Parker, JO4
  • 3
    • 0023196444 scopus 로고
    • Effect of intervals between doses on the development of tolerance to isosorbide dinitrate
    • JO Parker B Farrell KA Lahey G Moe Effect of intervals between doses on the development of tolerance to isosorbide dinitrate N Engl J Med 316 1987 1440 1444
    • (1987) N Engl J Med , vol.316 , pp. 1440-1444
    • Parker, JO1    Farrell, B2    Lahey, KA3    Moe, G4
  • 4
    • 0026566215 scopus 로고
    • Preventive administration of intravenous N-acetylcysteine and development of tolerance to isosorbide dinitrate in patients with angina pectoris
    • S Boesgaard J Aldershvile HE Poulsen Preventive administration of intravenous N-acetylcysteine and development of tolerance to isosorbide dinitrate in patients with angina pectoris Circulation 85 1992 143 149
    • (1992) Circulation , vol.85 , pp. 143-149
    • Boesgaard, S1    Aldershvile, J2    Poulsen, HE3
  • 6
    • 0027455003 scopus 로고
    • Conversion of glyceryl trinitrate to nitric oxide in tolerant and non-tolerant smooth muscle and endothelial cells
    • D Salvemini A Pistelli J Vane Conversion of glyceryl trinitrate to nitric oxide in tolerant and non-tolerant smooth muscle and endothelial cells Br J Pharmacol 108 1993 162 169
    • (1993) Br J Pharmacol , vol.108 , pp. 162-169
    • Salvemini, D1    Pistelli, A2    Vane, J3
  • 7
    • 0026009427 scopus 로고
    • Reduced nitric oxide release causes nitrate tolerance in the intact coronary circulation
    • S Förster I Woditsch H Schröder K Schrör Reduced nitric oxide release causes nitrate tolerance in the intact coronary circulation J Cardiovasc Pharmacol 17 1991 867 872
    • (1991) J Cardiovasc Pharmacol , vol.17 , pp. 867-872
    • Förster, S1    Woditsch, I2    Schröder, H3    Schrör, K4
  • 8
    • 0027528328 scopus 로고
    • Relationship between nitroglycerin-induced vascular relaxation and nitric oxide production
    • SJ Chung HL Fung Relationship between nitroglycerin-induced vascular relaxation and nitric oxide production Biochem Pharmacol 45 1993 157 163
    • (1993) Biochem Pharmacol , vol.45 , pp. 157-163
    • Chung, SJ1    Fung, HL2
  • 9
    • 0015595425 scopus 로고
    • Mechanisms of tolerance development to organic nitrates
    • P Needleman EM Johnson Mechanisms of tolerance development to organic nitrates J Pharmacol Exp Ther 184 1972 709 715
    • (1972) J Pharmacol Exp Ther , vol.184 , pp. 709-715
    • Needleman, P1    Johnson, EM2
  • 10
    • 0015713177 scopus 로고
    • Sulfhydryl requirement for relaxation of vascular smooth muscle
    • P Needleman B Jakschik EM Johnson Sulfhydryl requirement for relaxation of vascular smooth muscle J Pharmacol Exp Ther 187 1973 324 331
    • (1973) J Pharmacol Exp Ther , vol.187 , pp. 324-331
    • Needleman, P1    Jakschik, B2    Johnson, EM3
  • 11
    • 0019313372 scopus 로고
    • Requirements of thiols for activation of coronary arterial guanylate cyclase by glyceryl trinitrate and sodium nitrite: Possible involvement of S-nitrosothiols
    • LJ Ignarro CA Gruetter Requirements of thiols for activation of coronary arterial guanylate cyclase by glyceryl trinitrate and sodium nitrite Possible involvement of S-nitrosothiols Biochim Biophys Acta 631 1980 221 231
    • (1980) Biochim Biophys Acta , vol.631 , pp. 221-231
    • Ignarro, LJ1    Gruetter, CA2
  • 12
  • 13
    • 0027501074 scopus 로고
    • Biochemical characterization of a membrane-bound enzyme responsible for generating nitric oxide from nitroglycerin in vascular smooth muscle cells
    • P Seth HL Fung Biochemical characterization of a membrane-bound enzyme responsible for generating nitric oxide from nitroglycerin in vascular smooth muscle cells Biochem Pharmacol 46 1993 1481 1486
    • (1993) Biochem Pharmacol , vol.46 , pp. 1481-1486
    • Seth, P1    Fung, HL2
  • 14
    • 0028054830 scopus 로고
    • Nitrate tolerance in vivo is not associated with depletion of arterial or venous thiol levels
    • S Boesgaard J Aldershvile HE Poulsen S Loft ME Anderson A Meister Nitrate tolerance in vivo is not associated with depletion of arterial or venous thiol levels Circ Res 74 1994 115 120
    • (1994) Circ Res , vol.74 , pp. 115-120
    • Boesgaard, S1    Aldershvile, J2    Poulsen, HE3    Loft, S4    Anderson, ME5    Meister, A6
  • 15
    • 0028799761 scopus 로고
    • Evidence for enhanced vascular superoxide anion production in nitrate tolerance
    • T Münzel H Sayegh BA Freeman M Tarpey DG Harrison Evidence for enhanced vascular superoxide anion production in nitrate tolerance J Clin Invest 95 1995 187 194
    • (1995) J Clin Invest , vol.95 , pp. 187-194
    • Münzel, T1    Sayegh, H2    Freeman, BA3    Tarpey, M4    Harrison, DG5
  • 16
    • 10244278106 scopus 로고
    • Similarities and discrepancies between in vivo and in vitro nitrate tolerance. (Abstr.)
    • T Münzel S Kurz M Tarpey BA Freeman DG Harrison Similarities and discrepancies between in vivo and in vitro nitrate tolerance. (Abstr.) Circulation 92 suppl 1995 I4
    • (1995) Circulation , vol.92 , Issue.suppl , pp. I4
    • Münzel, T1    Kurz, S2    Tarpey, M3    Freeman, BA4    Harrison, DG5
  • 17
    • 0024473451 scopus 로고
    • Endothelium- and sydnonimine-dependent responses of native and cultured aortic smooth muscle cells are not impaired by nitroglycerin tolerance
    • A Mülsch R Busse I Winter E Bassenge Endothelium- and sydnonimine-dependent responses of native and cultured aortic smooth muscle cells are not impaired by nitroglycerin tolerance Naunyn Schmiedebergs Arch Pharmacol 339 1989 568 574
    • (1989) Naunyn Schmiedebergs Arch Pharmacol , vol.339 , pp. 568-574
    • Mülsch, A1    Busse, R2    Winter, I3    Bassenge, E4
  • 18
    • 0026343403 scopus 로고
    • Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy
    • A Meister Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy Pharmacol Ther 51 1991 155 194
    • (1991) Pharmacol Ther , vol.51 , pp. 155-194
    • Meister, A1
  • 19
    • 0021228410 scopus 로고
    • New developments in glutathione metabolism and their potential application in therapy
    • A Meister New developments in glutathione metabolism and their potential application in therapy Hepatology 4 1984 739 742
    • (1984) Hepatology , vol.4 , pp. 739-742
    • Meister, A1
  • 20
    • 0022460516 scopus 로고
    • Intracellular cysteine and glutathione delivery systems
    • A Meister ME Anderson O Hwang Intracellular cysteine and glutathione delivery systems J Am Coll Nutr 5 1986 137 151
    • (1986) J Am Coll Nutr , vol.5 , pp. 137-151
    • Meister, A1    Anderson, ME2    Hwang, O3
  • 21
    • 0023081006 scopus 로고
    • Intracellular delivery of cysteine
    • ME Anderson A Meister Intracellular delivery of cysteine Meth Enzym 143 1987 313 325
    • (1987) Meth Enzym , vol.143 , pp. 313-325
    • Anderson, ME1    Meister, A2
  • 22
    • 2842598462 scopus 로고
    • Stimulation of hepatic glutathione formation by administration of L-2-oxothiazolidine-4-carboxylate: A 5-oxo-L-prolinase substrate
    • JM Williamson A Meister Stimulation of hepatic glutathione formation by administration of L-2-oxothiazolidine-4-carboxylate A 5-oxo-L-prolinase substrate Proc Natl Acad Sci USA 78 1981 936 939
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 936-939
    • Williamson, JM1    Meister, A2
  • 23
    • 0018666729 scopus 로고
    • Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-N-butyl homocysteine sulfoximine)
    • OW Griffith A Meister Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-N-butyl homocysteine sulfoximine) J Biol Chem 254 1979 7558 7560
    • (1979) J Biol Chem , vol.254 , pp. 7558-7560
    • Griffith, OW1    Meister, A2
  • 24
    • 0014703826 scopus 로고
    • Tolerance to the vascular effects of glyceryl trinitrate
    • P Needleman Tolerance to the vascular effects of glyceryl trinitrate J Pharmacol Exp Ther 171 1969 98 102
    • (1969) J Pharmacol Exp Ther , vol.171 , pp. 98-102
    • Needleman, P1
  • 25
    • 0021792298 scopus 로고
    • Prevention and reversal of tolerance to nitroglycerin with N-acetylcysteine
    • JT Torresi JD Horowitz GJ Dusting Prevention and reversal of tolerance to nitroglycerin with N-acetylcysteine J Cardiovasc Pharmacol 7 1985 777 783
    • (1985) J Cardiovasc Pharmacol , vol.7 , pp. 777-783
    • Torresi, JT1    Horowitz, JD2    Dusting, GJ3
  • 26
    • 0022859971 scopus 로고
    • Effects of sulfhydryl reagents on nitroglycerin-induced relaxation of bovine coronary artery
    • CA Gruetter SM Lemke Effects of sulfhydryl reagents on nitroglycerin-induced relaxation of bovine coronary artery Can J Physiol Pharmacol 64 1986 1395 1401
    • (1986) Can J Physiol Pharmacol , vol.64 , pp. 1395-1401
    • Gruetter, CA1    Lemke, SM2
  • 27
    • 0025784467 scopus 로고
    • L-cysteine selectivity potentiates nitroglycerin-induced dilation of small coronary microvessels
    • FW Sellke RJ Tomanek DG Harrison L-cysteine selectivity potentiates nitroglycerin-induced dilation of small coronary microvessels J Pharmacol Exp Ther 258 1991 365 369
    • (1991) J Pharmacol Exp Ther , vol.258 , pp. 365-369
    • Sellke, FW1    Tomanek, RJ2    Harrison, DG3
  • 28
    • 0022574514 scopus 로고
    • Potentiation of nitroglycerin-induced coronary dilatation by N-acetylcysteine
    • MD Winniford PL Kennedy PJ Wells LD Hillis Potentiation of nitroglycerin-induced coronary dilatation by N-acetylcysteine Circulation 73 1986 138 142
    • (1986) Circulation , vol.73 , pp. 138-142
    • Winniford, MD1    Kennedy, PL2    Wells, PJ3    Hillis, LD4
  • 29
    • 0023663712 scopus 로고
    • In vivo induction and reversal of nitroglycerin tolerance in human coronary arteries
    • DC May JJ Popma WH Black S Schaeffer HR Lee BD Levine LD Hillis In vivo induction and reversal of nitroglycerin tolerance in human coronary arteries N Engl J Med 317 1987 805 809
    • (1987) N Engl J Med , vol.317 , pp. 805-809
    • May, DC1    Popma, JJ2    Black, WH3    Schaeffer, S4    Lee, HR5    Levine, BD6    Hillis, LD7
  • 30
    • 0026096611 scopus 로고
    • Mechanisms responsible for the heterogeneous coronary microvascular response to nitroglycerin
    • MA Kurz KG Lamping JN Bates CL Eastham ML Marcus DG Harrison Mechanisms responsible for the heterogeneous coronary microvascular response to nitroglycerin Circ Res 68 1991 847 855
    • (1991) Circ Res , vol.68 , pp. 847-855
    • Kurz, MA1    Lamping, KG2    Bates, JN3    Eastham, CL4    Marcus, ML5    Harrison, DG6
  • 31
    • 0025831603 scopus 로고
    • Methionine restores the venodilative response to nitroglycerin after the development of tolerance
    • WS Levy RJ Katz AG Wasserman Methionine restores the venodilative response to nitroglycerin after the development of tolerance J Am Coll Cardiol 17 1991 474 479
    • (1991) J Am Coll Cardiol , vol.17 , pp. 474-479
    • Levy, WS1    Katz, RJ2    Wasserman, AG3
  • 32
    • 0021019453 scopus 로고
    • Potentiation of the cardiovascular effects of nitroglycerin by N-acetylcysteine
    • JD Horowitz EM Antman BH Lorell WH Barry TW Smith Potentiation of the cardiovascular effects of nitroglycerin by N-acetylcysteine Circulation 68 1983 1247 1253
    • (1983) Circulation , vol.68 , pp. 1247-1253
    • Horowitz, JD1    Antman, EM2    Lorell, BH3    Barry, WH4    Smith, TW5
  • 33
    • 0023911420 scopus 로고
    • Mechanisms for the pharmacologic interaction of organic nitrates with thiols: Existence of an extracellular pathway for the reversal of nitrate vascular tolerance by N-acetylcysteine
    • HL Fung S Chong E Kowaluk K Hough M Kakemi Mechanisms for the pharmacologic interaction of organic nitrates with thiols Existence of an extracellular pathway for the reversal of nitrate vascular tolerance by N-acetylcysteine J Pharmacol Exp Ther 245 1988 524 530
    • (1988) J Pharmacol Exp Ther , vol.245 , pp. 524-530
    • Fung, HL1    Chong, S2    Kowaluk, E3    Hough, K4    Kakemi, M5
  • 34
    • 0025942551 scopus 로고
    • Nitrate tolerance: effect of thiol supplementation during prolonged nitroglycerin infusion in an in vivo rat model
    • S Boesgaard JS Petersen J Aldershvile HE Poulsen H Flachs Nitrate tolerance effect of thiol supplementation during prolonged nitroglycerin infusion in an in vivo rat model J Pharmacol Exp Ther 258 1991 851 856
    • (1991) J Pharmacol Exp Ther , vol.258 , pp. 851-856
    • Boesgaard, S1    Petersen, JS2    Aldershvile, J3    Poulsen, HE4    Flachs, H5
  • 35
    • 0021966240 scopus 로고
    • Disassociation of cysteine and glutathione levels from nitroglycerin-induced relaxation
    • CA Gruetter SM Lemke Disassociation of cysteine and glutathione levels from nitroglycerin-induced relaxation Eur J Pharmacol 111 1985 85 95
    • (1985) Eur J Pharmacol , vol.111 , pp. 85-95
    • Gruetter, CA1    Lemke, SM2
  • 36
    • 0020379708 scopus 로고
    • Investigations into the role of sulfhydryl groups in the mechanism of action of nitrates
    • JA Moffat PW Armstrong GS Marks Investigations into the role of sulfhydryl groups in the mechanism of action of nitrates Can J Physiol Pharmacol 60 1981 1261 1266
    • (1981) Can J Physiol Pharmacol , vol.60 , pp. 1261-1266
    • Moffat, JA1    Armstrong, PW2    Marks, GS3
  • 37
    • 0024565987 scopus 로고
    • Nitroglycerin-induced tolerance affects multiple sites in the organic nitrate bioconversion cascade
    • PJ Henry JD Horowitz WJ Louis Nitroglycerin-induced tolerance affects multiple sites in the organic nitrate bioconversion cascade J Pharmacol Exp Ther 248 1991 762 768
    • (1991) J Pharmacol Exp Ther , vol.248 , pp. 762-768
    • Henry, PJ1    Horowitz, JD2    Louis, WJ3
  • 38
    • 0023277458 scopus 로고
    • Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase
    • M Feelisch EA Noack Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase Eur J Pharmacol 139 1987 19 30
    • (1987) Eur J Pharmacol , vol.139 , pp. 19-30
    • Feelisch, M1    Noack, EA2
  • 39
    • 0025880486 scopus 로고
    • Biochemical and pharmacological interactions between nitroglycerin and thiols
    • S Chong HL Fung Biochemical and pharmacological interactions between nitroglycerin and thiols Biochem Pharmacol 42 1991 1433 1439
    • (1991) Biochem Pharmacol , vol.42 , pp. 1433-1439
    • Chong, S1    Fung, HL2
  • 40
    • 0026024563 scopus 로고
    • Captopril-induced reversal of nitroglycerin tolerance: role of sulfhydryl group vs. ACE-inhibitory activity
    • DL Lawson WW Nichols P Mehta JL Mehta Captopril-induced reversal of nitroglycerin tolerance role of sulfhydryl group vs. ACE-inhibitory activity J Cardiovasc Pharmacol 17 1991 411 414
    • (1991) J Cardiovasc Pharmacol , vol.17 , pp. 411-414
    • Lawson, DL1    Nichols, WW2    Mehta, P3    Mehta, JL4
  • 41
    • 0025319218 scopus 로고
    • Rapid tolerance to the hypotensive effects of glyceryl trinitrate in the rat: prevention by N-acetyl-L- but not N-acetyl-d-cysteine
    • CM Newman JB Warren GW Taylor AR Boobis DS Davies Rapid tolerance to the hypotensive effects of glyceryl trinitrate in the rat prevention by N-acetyl-L- but not N-acetyl- d -cysteine Br J Pharmacol 99 1990 825 829
    • (1990) Br J Pharmacol , vol.99 , pp. 825-829
    • Newman, CM1    Warren, JB2    Taylor, GW3    Boobis, AR4    Davies, DS5
  • 42
    • 0028157847 scopus 로고
    • Interactions of nitroglycerin and sulfhydryl-donating compounds in coronary microvessels
    • RM Wheatley SP Dockery MA Kurz HS Saygeh DG Harrison Interactions of nitroglycerin and sulfhydryl-donating compounds in coronary microvessels Am J Physiol 266 1994 H291 H297
    • (1994) Am J Physiol , vol.266 , pp. H291-H297
    • Wheatley, RM1    Dockery, SP2    Kurz, MA3    Saygeh, HS4    Harrison, DG5
  • 43
    • 0025357203 scopus 로고
    • Purification and characterization of glutathione transferases with an activity toward nitroglycerin from human aorta and heart
    • S Tsuchida T Maki K Sato Purification and characterization of glutathione transferases with an activity toward nitroglycerin from human aorta and heart J Biol Chem 265 1990 7150 7157
    • (1990) J Biol Chem , vol.265 , pp. 7150-7157
    • Tsuchida, S1    Maki, T2    Sato, K3
  • 44
    • 0026595087 scopus 로고
    • Metabolism of nitroglycerin by smooth muscle cells: Involvement of glutathione and glutathione S-transferase
    • KE Hill RW Hunt R Jones RL Hoover RF Burk Metabolism of nitroglycerin by smooth muscle cells Involvement of glutathione and glutathione S-transferase Biochem Pharmacol 43 1992 561 566
    • (1992) Biochem Pharmacol , vol.43 , pp. 561-566
    • Hill, KE1    Hunt, RW2    Jones, R3    Hoover, RL4    Burk, RF5
  • 45
    • 0026680866 scopus 로고
    • Cytochrome P-450 mediates bioactivation of organic nitrates
    • H Schröder Cytochrome P-450 mediates bioactivation of organic nitrates J Pharmacol Exp Ther 262 1992 298 302
    • (1992) J Pharmacol Exp Ther , vol.262 , pp. 298-302
    • Schröder, H1
  • 46
    • 0026752722 scopus 로고
    • Hepatic cytochrome P–450-mediated activation of rat aortic guanylyl cyclase by glyceryl trinitrate
    • BM Bennet BJ McDonald MJ St. James Hepatic cytochrome P–450-mediated activation of rat aortic guanylyl cyclase by glyceryl trinitrate J Pharmacol Exp Ther 261 1992 716 721
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 716-721
    • Bennet, BM1    McDonald, BJ2    St. James, MJ3
  • 48
    • 85119464933 scopus 로고
    • Guanylate cyclase activation by organic nitrates is not mediated via nitrite
    • C Ramanin WR Kukovetz Guanylate cyclase activation by organic nitrates is not mediated via nitrite J Mol Cell Cardiol 21 1989 21 48
    • (1989) J Mol Cell Cardiol , vol.21 , pp. 21-48
    • Ramanin, C1    Kukovetz, WR2
  • 49
    • 0025316693 scopus 로고
    • Identification of the subcellular site for nitroglycerin metabolism to nitric oxide in bovine coronary smooth muscle cells
    • SJ Chung HL Fung Identification of the subcellular site for nitroglycerin metabolism to nitric oxide in bovine coronary smooth muscle cells J Pharmacol Exp Ther 253 1990 614 619
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 614-619
    • Chung, SJ1    Fung, HL2
  • 50
    • 0024394697 scopus 로고
    • The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid
    • OI Aruoma B Halliwell BM Hoey J Butler The antioxidant action of N-acetylcysteine its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid Free Radic Biol Med 6 1989 593 597
    • (1989) Free Radic Biol Med , vol.6 , pp. 593-597
    • Aruoma, OI1    Halliwell, B2    Hoey, BM3    Butler, J4
  • 51
    • 0023936709 scopus 로고
    • The role of glutathione status in the protection against ischaemic and reperfusion damage: effects of N-acetylcysteine
    • C Ceconi S Curello A Cargnoni R Ferrari A Albertini O Visioli The role of glutathione status in the protection against ischaemic and reperfusion damage effects of N-acetylcysteine J Mol Cell Cardiol 20 1988 5 13
    • (1988) J Mol Cell Cardiol , vol.20 , pp. 5-13
    • Ceconi, C1    Curello, S2    Cargnoni, A3    Ferrari, R4    Albertini, A5    Visioli, O6
  • 52
    • 0027104253 scopus 로고
    • Biochemistry of nitric oxide and its redox-activated forms
    • JS Stamler DJ Singel J Loscalzo Biochemistry of nitric oxide and its redox-activated forms Science 258 1992 1898 1902
    • (1992) Science , vol.258 , pp. 1898-1902
    • Stamler, JS1    Singel, DJ2    Loscalzo, J3
  • 53
    • 0025349882 scopus 로고
    • Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide
    • PR Myers RL Minor R Guerra JN Bates DG Harrison Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide Nature 345 1990 161 163
    • (1990) Nature , vol.345 , pp. 161-163
    • Myers, PR1    Minor, RL2    Guerra, R3    Bates, JN4    Harrison, DG5
  • 54
    • 0027472139 scopus 로고
    • Acute effects of nitroglycerin depend on both plasma and intracellular sulfhydryl compound levels in vivo
    • S Boesgaard HE Poulsen J Aldershvile S Loft ME Anderson A Meister Acute effects of nitroglycerin depend on both plasma and intracellular sulfhydryl compound levels in vivo Circulation 87 1993 547 553
    • (1993) Circulation , vol.87 , pp. 547-553
    • Boesgaard, S1    Poulsen, HE2    Aldershvile, J3    Loft, S4    Anderson, ME5    Meister, A6
  • 56
    • 0024504555 scopus 로고
    • Nitrate tolerance in epicardial arteries or in the venous system is not reversed by N-acetylcysteine in vivo, but tolerance independent interactions exist
    • T Münzel J Holtz A Mülsch DJ Stewart E Bassenge Nitrate tolerance in epicardial arteries or in the venous system is not reversed by N-acetylcysteine in vivo, but tolerance independent interactions exist Circulation 79 1988 188 197
    • (1988) Circulation , vol.79 , pp. 188-197
    • Münzel, T1    Holtz, J2    Mülsch, A3    Stewart, DJ4    Bassenge, E5
  • 57
    • 0029997902 scopus 로고    scopus 로고
    • Nitrate tolerance impairs nitric oxide-mediated vasodilation in vivo
    • JB Laursen S Boesgaard HE Poulsen J Aldershvile Nitrate tolerance impairs nitric oxide-mediated vasodilation in vivo Cardiovasc Res 31 1996 814 819
    • (1996) Cardiovasc Res , vol.31 , pp. 814-819
    • Laursen, JB1    Boesgaard, S2    Poulsen, HE3    Aldershvile, J4
  • 58
    • 0026788448 scopus 로고
    • Mechanism of interaction between sulfhydryl precursor L-methionine and glyceryl trinitrate
    • T Münzel A Mülsch J Holtz H Just DG Harrison E Bassenge Mechanism of interaction between sulfhydryl precursor L-methionine and glyceryl trinitrate Circulation 86 1992 995 1003
    • (1992) Circulation , vol.86 , pp. 995-1003
    • Münzel, T1    Mülsch, A2    Holtz, J3    Just, H4    Harrison, DG5    Bassenge, E6
  • 59
    • 0019967216 scopus 로고
    • Vascular smooth muscle relaxation by nitro compounds: reduced relaxation and cGMP elevation in tolerant vessels and reversal of tolerance by dithiothreitol
    • KL Axelsson RGG Andersson JES Wikberg Vascular smooth muscle relaxation by nitro compounds reduced relaxation and cGMP elevation in tolerant vessels and reversal of tolerance by dithiothreitol Acta Pharmacol Toxicol 50 1982 350 357
    • (1982) Acta Pharmacol Toxicol , vol.50 , pp. 350-357
    • Axelsson, KL1    Andersson, RGG2    Wikberg, JES3
  • 60
    • 0021210841 scopus 로고
    • Nitroglycerin tolerance in vitro: effect on cGMP turnover in vascular smooth muscle
    • KL Axelsson JO Karlsson Nitroglycerin tolerance in vitro effect on cGMP turnover in vascular smooth muscle Acta Pharmacol Toxicol 55 1994 203 210
    • (1994) Acta Pharmacol Toxicol , vol.55 , pp. 203-210
    • Axelsson, KL1    Karlsson, JO2
  • 61
    • 0023092489 scopus 로고
    • Different sensitivities of arteries and veins to glyceryltrinitrate-induced relaxation and tolerance: an “in vitro” study on isolated vessels from rabbits
    • R Rösen E König W Klaus Different sensitivities of arteries and veins to glyceryltrinitrate-induced relaxation and tolerance an “in vitro” study on isolated vessels from rabbits Arch Int Pharmacodyn Ther 285 1987 226 237
    • (1987) Arch Int Pharmacodyn Ther , vol.285 , pp. 226-237
    • Rösen, R1    König, E2    Klaus, W3
  • 62
    • 0028200080 scopus 로고
    • Potentiation of isosorbide dinitrate effects with N-acetylcysteine in patients with chronic heart failure
    • A Mehra A Shotan E Ostrzega W Hsueh VJ Johnson U Elkayam Potentiation of isosorbide dinitrate effects with N-acetylcysteine in patients with chronic heart failure Circulation 89 1994 2596 2600
    • (1994) Circulation , vol.89 , pp. 2596-2600
    • Mehra, A1    Shotan, A2    Ostrzega, E3    Hsueh, W4    Johnson, VJ5    Elkayam, U6
  • 63
    • 0025319836 scopus 로고
    • Mechanisms of nitrate-induced vasodilatation and tolerance
    • WR Kukovetz S Holzmann Mechanisms of nitrate-induced vasodilatation and tolerance Eur J Clin Pharmacol 38 suppl 1 1990 9 14
    • (1990) Eur J Clin Pharmacol , vol.38 , Issue.suppl 1 , pp. 9-14
    • Kukovetz, WR1    Holzmann, S2
  • 64
    • 0025834639 scopus 로고
    • Nitroglycerin relaxes coronary artery of the pig with no change in glutathione content or glutathione S-transferase activity
    • M Sakanashi T Matsuzaki Y Aniya Nitroglycerin relaxes coronary artery of the pig with no change in glutathione content or glutathione S-transferase activity Br J Pharmacol 103 1991 1905 1908
    • (1991) Br J Pharmacol , vol.103 , pp. 1905-1908
    • Sakanashi, M1    Matsuzaki, T2    Aniya, Y3
  • 65
    • 0023240541 scopus 로고
    • Prevention and reversal of nitrate tolerance in patients with congestive heart failure
    • M Packer WH Lee PD Kessler SS Gottlieb N Medina M Yushak Prevention and reversal of nitrate tolerance in patients with congestive heart failure N Engl J Med 317 1987 799 804
    • (1987) N Engl J Med , vol.317 , pp. 799-804
    • Packer, M1    Lee, WH2    Kessler, PD3    Gottlieb, SS4    Medina, N5    Yushak, M6
  • 66
    • 0030433664 scopus 로고    scopus 로고
    • In vivo depletion of free thiols does not account for nitroglycerin-induced tolerance: a thiol-nitrate interaction hypothesis as an alternative explanation for nitroglycerin activity and tolerance
    • AI Haj-Yehia LZ Benet In vivo depletion of free thiols does not account for nitroglycerin-induced tolerance a thiol-nitrate interaction hypothesis as an alternative explanation for nitroglycerin activity and tolerance J Pharmacol Exp Ther 278 1996 1296 1305
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 1296-1305
    • Haj-Yehia, AI1    Benet, LZ2
  • 67
    • 0025747926 scopus 로고
    • Counterregulatory responses to continuous and intermittent therapy with nitroglycerin
    • JD Parker IJ Farrell T Fenton M Cohanim JO Parker Counterregulatory responses to continuous and intermittent therapy with nitroglycerin Circulation 84 1991 2336 2345
    • (1991) Circulation , vol.84 , pp. 2336-2345
    • Parker, JD1    Farrell, IJ2    Fenton, T3    Cohanim, M4    Parker, JO5
  • 68
    • 0029889534 scopus 로고    scopus 로고
    • New insights into mechanisms underlying nitrate tolerance
    • T Münzel S Kurz T Heitzer DG Harrison New insights into mechanisms underlying nitrate tolerance Am J Cardiol 77 1996 24C 30C
    • (1996) Am J Cardiol , vol.77 , pp. 24C-30C
    • Münzel, T1    Kurz, S2    Heitzer, T3    Harrison, DG4
  • 70
    • 0028799761 scopus 로고
    • Evidence for enhanced vascular superoxide anion production in nitrate tolerance
    • T Münzel H Saygh BA Freeman M Tarpey DG Harrison Evidence for enhanced vascular superoxide anion production in nitrate tolerance J Clin Invest 95 1995 187 194
    • (1995) J Clin Invest , vol.95 , pp. 187-194
    • Münzel, T1    Saygh, H2    Freeman, BA3    Tarpey, M4    Harrison, DG5
  • 71
    • 0024331806 scopus 로고
    • Inhibition of development of tolerance to nitroglycerin by preventive administration of N-acetylcysteine in rats
    • H Tsuneyoshi N Akatsuka M Ohno K Hara M Ochiai M Moroi Inhibition of development of tolerance to nitroglycerin by preventive administration of N-acetylcysteine in rats Jpn Heart J 30 1989 733 741
    • (1989) Jpn Heart J , vol.30 , pp. 733-741
    • Tsuneyoshi, H1    Akatsuka, N2    Ohno, M3    Hara, K4    Ochiai, M5    Moroi, M6
  • 72
    • 0026567721 scopus 로고
    • Lack of tolerance to a 24-hour infusion of S-nitroso N-acetylpenicillamine (SNAP) in conscious rabbits
    • JE Shaffer BJ Han WH Chern FW Lee Lack of tolerance to a 24-hour infusion of S-nitroso N-acetylpenicillamine (SNAP) in conscious rabbits J Pharmacol Exp Ther 260 1992 286 293
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 286-293
    • Shaffer, JE1    Han, BJ2    Chern, WH3    Lee, FW4
  • 73
    • 0023881640 scopus 로고
    • Combined use of nitroglycerin and N-acetylcysteine in the management of unstable angina pectoris
    • JD Horowitz CA Henry ML Syrjanen WJ Louis RD Fish TW Smith EM Antman Combined use of nitroglycerin and N-acetylcysteine in the management of unstable angina pectoris Circulation 77 1988 787 794
    • (1988) Circulation , vol.77 , pp. 787-794
    • Horowitz, JD1    Henry, CA2    Syrjanen, ML3    Louis, WJ4    Fish, RD5    Smith, TW6    Antman, EM7
  • 75
    • 0023202648 scopus 로고
    • The effect of isosorbide dinitrate on the arterial bed: a dose response study in dogs
    • J Aldershvile U Abildgaard P Elisasen O Amtorp The effect of isosorbide dinitrate on the arterial bed a dose response study in dogs Pharmacol Toxicol 61 1987 116 120
    • (1987) Pharmacol Toxicol , vol.61 , pp. 116-120
    • Aldershvile, J1    Abildgaard, U2    Elisasen, P3    Amtorp, O4
  • 76
    • 0025357406 scopus 로고
    • Influence of vessel size on the sensitivity of porcine coronary microvessels to nitroglycerin
    • FW Sellke PR Myers JN Bates DG Harrison Influence of vessel size on the sensitivity of porcine coronary microvessels to nitroglycerin Am J Physiol 258 1990 H515 H520
    • (1990) Am J Physiol , vol.258 , pp. H515-H520
    • Sellke, FW1    Myers, PR2    Bates, JN3    Harrison, DG4
  • 77
    • 0022473497 scopus 로고
    • Altered spectrum of nitroglycerin action in long-term treatment: nitroglycerin-specific venous tolerance with maintenance of arterial vasodepressor potency
    • DJ Stewart MD Elsner O Sommer J Holtz E Bassenge Altered spectrum of nitroglycerin action in long-term treatment nitroglycerin-specific venous tolerance with maintenance of arterial vasodepressor potency Circulation 74 1986 573 582
    • (1986) Circulation , vol.74 , pp. 573-582
    • Stewart, DJ1    Elsner, MD2    Sommer, O3    Holtz, J4    Bassenge, E5
  • 78
    • 0026800817 scopus 로고
    • Different susceptibility to the development of nitroglycerin tolerance in the arterial and venous circulation in humans
    • S Ghio S de Servi R Perotti E Eleuteri C Montemartini G Specchia Different susceptibility to the development of nitroglycerin tolerance in the arterial and venous circulation in humans Circulation 86 1992 798 802
    • (1992) Circulation , vol.86 , pp. 798-802
    • Ghio, S1    de Servi, S2    Perotti, R3    Eleuteri, E4    Montemartini, C5    Specchia, G6
  • 79
    • 0026676903 scopus 로고
    • Desensitization of nitrate-induced venodilation: reversal with oral N-acetylcysteine in humans
    • J Vincent S Kongpatanakul TF Blascke BB Hoffman Desensitization of nitrate-induced venodilation reversal with oral N-acetylcysteine in humans J Cardiovasc Pharmacol 20 1992 907 912
    • (1992) J Cardiovasc Pharmacol , vol.20 , pp. 907-912
    • Vincent, J1    Kongpatanakul, S2    Blascke, TF3    Hoffman, BB4
  • 80
    • 0026774990 scopus 로고
    • N-acetylcysteine enhances nitroglycerin-induced headache and cranial arterial responses
    • HK Iversen N-acetylcysteine enhances nitroglycerin-induced headache and cranial arterial responses Clin Pharmacol Ther 52 1992 125 133
    • (1992) Clin Pharmacol Ther , vol.52 , pp. 125-133
    • Iversen, HK1
  • 81
    • 0028881707 scopus 로고
    • N-acetylcysteine in combination with nitroglycerin and streptokinase for the treatment of evolving acute myocardial infarction
    • MA Arstall J Yang I Stafford WH Betts JD Horowitz N-acetylcysteine in combination with nitroglycerin and streptokinase for the treatment of evolving acute myocardial infarction Circulation 92 1995 2855 2862
    • (1995) Circulation , vol.92 , pp. 2855-2862
    • Arstall, MA1    Yang, J2    Stafford, I3    Betts, WH4    Horowitz, JD5
  • 82
    • 0023250954 scopus 로고
    • Nitrate tolerance: the lack of effect of N-acetylcysteine
    • JO Parker B Farrell KA Lahey BF Rose Nitrate tolerance the lack of effect of N-acetylcysteine Circulation 76 1987 572 576
    • (1987) Circulation , vol.76 , pp. 572-576
    • Parker, JO1    Farrell, B2    Lahey, KA3    Rose, BF4
  • 83
    • 0023835113 scopus 로고
    • Pharmacokinetics and bioavailability of reduced and oxidized N-acetylcysteine
    • B Olsson M Johansson J Gabrielsson P Bolme Pharmacokinetics and bioavailability of reduced and oxidized N-acetylcysteine Eur J Clin Pharmacol 34 1988 77 82
    • (1988) Eur J Clin Pharmacol , vol.34 , pp. 77-82
    • Olsson, B1    Johansson, M2    Gabrielsson, J3    Bolme, P4
  • 84
    • 0024999691 scopus 로고
    • Chronic administration of N-acetylcysteine fails to prevent nitrate tolerance in patients with stable angina pectoris
    • JC Hogan AH Henderson Chronic administration of N-acetylcysteine fails to prevent nitrate tolerance in patients with stable angina pectoris Br J Clin Pharmacol 30 1990 573 577
    • (1990) Br J Clin Pharmacol , vol.30 , pp. 573-577
    • Hogan, JC1    Henderson, AH2
  • 85
    • 0026009430 scopus 로고
    • Continuous oral N-acetylcysteine treatment and development of nitrate tolerance in patients with stable angina pectoris
    • S Boesgaard J Aldershvile F Pedersen A Pietersen JK Madsen P Grande Continuous oral N-acetylcysteine treatment and development of nitrate tolerance in patients with stable angina pectoris J Cardiovasc Pharmacol 17 1991 889 893
    • (1991) J Cardiovasc Pharmacol , vol.17 , pp. 889-893
    • Boesgaard, S1    Aldershvile, J2    Pedersen, F3    Pietersen, A4    Madsen, JK5    Grande, P6
  • 86
    • 85119467056 scopus 로고    scopus 로고
    • Dan Med Bull.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.