Cutaneous leishmaniasis in the peruvian andes: Factors associated with variability in clinical symptoms, response to treatment, and parasite isolation rate

Clinical Infectious Diseases

Volumn 25, Issue 2, 1997, Pages 302-310

  Davies, Clive R ^a   Llanos Cuentas, E Alejandro ^b   Sharp, Stephen J ^b   Canales, Juan ^b   Leon, Elida ^b   Alvarez, Eugenia ^b   Roncal, Norma ^b   Dye, Christopher ^b  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMONY DERIVATIVE;

ADOLESCENT; ADULT; AGED; ARTICLE; COST EFFECTIVENESS ANALYSIS; FEMALE; GEOGRAPHIC DISTRIBUTION; HOST PARASITE INTERACTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL DECISION MAKING; MULTIVARIATE ANALYSIS; OCCUPATIONAL EXPOSURE; PARASITE ISOLATION; PARASITE TRANSMISSION; PARASITE VECTOR; PERU; PRIORITY JOURNAL; PSYCHODIDAE; SCAR; SKIN LEISHMANIASIS; SYMPTOMATOLOGY; VECTOR CONTROL;

EID: 0030858394     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/514535     Document Type: Article

References (23)

1. Dujardin JC, Llanos-Cuentas EA, Caceres A, et al. Molecular karyotype variation in Leishmania (Viannia) peruviana: indication of geographical populations in Peru distributed along a north-south cline. Ann Trop Med Parasitol 1993;87:335-47.
2. Davies CR, Llanos-Cuentas EA, Pyke SDM, Dye C. Cutaneous leishmaniasis in the Peruvian Andes: an epidemiological study of infection and immunity. Epiderniol Infect 1995;114:297-318.
3. Dujardin JC, Dujardin JP, Tibayrenc M, et al. Karyotype plasticity in neotropical Leishmania: an index for measuring genomic distance among L. (V.) peruviana and L. (V.) braziliensis populations. Parasitology 1995;110:21-30.
4. Espinoza J, Skinner AC, Davies CR, et al. Extensive polymorphism at the Gp63 locus in field isolates of Leishmania peruviana. Mol Biochem Parasitol 1995;72:203-13.
5. May RM, Anderson RM. Epidemiology and genetics in the coevolution of parasites and hosts. Proc R Soc Lond B Biol Sci 1983;219:281-313.
6. Dye CM, Davies CR. Glasnost and the great gerbil: virulence polymorphisms in the epidemiology of leishmaniasis. Trends in Ecology and Evolution 1990;5:237-8.
7. Davies CR, Llanos-Cuentas A, Canales J, et al. The fall and rise of Andean cutaneous leishmaniasis: transient impact of the DDT campaign in Peru. Trans R Soc Trop Med Hyg 1994;88:389-93.
8. Jones TC, Johnson WD Jr, Barretto AC, et al. Epidemiology of American cutaneous leishmaniasis due to Leishmania braziliensis braziliensis. J Infect Dis 1987;156:73-83.
9. Weigle KA, Santrich C, Martinez F, Valderramma L, Saravia NG. Epidemiology of cutaneous leishmaniasis in Colombia: environmental and behavioral risk factors for infection, clinical manifestations, and pathogenicity. J Infect Dis 1993;168:709-14.
10. Herrer A. Estudios sobre leishmaniasis tegumentaria en el Peru. IV. Observaciones epidemiologicas sobre la uta. Revista de Medicina Experimental 1951;8:45-86.
11. Hashiguchi Y. Studies on New World leishmaniasis and its transmission, with particular reference to Ecuador. Research Report Series No. 3. Kochi, Japan: Kyowa Printing & Co., 1992.
12. Dedet JP, Pradinaud R, Gay F. Epidemiological aspects of human cutaneous leishmaniasis in French Guiana. Trans R Soc Trop Med Hyg 1989;83:616-20.
13. Cuba Cuba CA, Netto EM, Marsden PD, Rosa AC, Llanos-Cuentas EA, Costa JLM. Cultivation of Leishmania braziliensis braziliensis from skin ulcers in man under field conditions. Trans R Soc Trop Med Hyg 1986;80:456-7.
14. De Bruijn MHL, Labrada LA, Smyth AJ, Santrich C, Barker DC. A comparative study by the polymerase chain reaction and by current clinical methods using biopsies from Colombian patients with suspected leishmaniasis. Trop Med Parasitol 1993;44:201-7.
15. Weigle KA, de Davalos M, Heredia P, Molineros R, Saravia NG, d'Allessandros A. Diagnosis of cutaneous and mucocutaneous Jeishmaniasis in Colombia: a comparison of seven methods. Am J Trop Med Hyg 1987;36:489-96.
16. Navin TR, Arana FE, de Merida AM, Arana BA, Castillo AL, Silvers DN. Cutaneous leishmaniasis in Guatemala: comparison of diagnostic methods. Am J Trop Med Hyg 1990;42:36-42.
17. Torres Espejo JM, Le Pont F, Mouchet J, Desjeux P, Richard A. Epidemiologie de la leishrnaniose tegumentaire en Bolivie. 1. Description des zones d'etude et frequence de la maladie. Ann Soc Belg Med Trop 1989;69:297-306.
18. Davies CR, Llanos-Cuentas EA, Campos P, Monge J, Villaseca P, Dye C. Cutaneous leishmaniasis in the Peruvian Andes: risk factors identified from a village cohort study. Am J Trop Med Hyg 1997;56: 85-95.
19. Weigle KA, Saravia NG, de Davalos M, Moreno LH, d'Allessandro A. Leishmania braziliensis from the Pacific coast region of Colombia: foci of transmission, clinical spectrum and isoenzyme phenotypes. Am J Trop Med Hyg 1986;35:722-31.
20. Lysenko AJ, Beljaev AE. Quantitative approaches to epidemiology. In: Peters W, Killick-Kendrick R, eds. The leishmaniases in biology and medicine. Vol 1. New York: Academic Press, 1987: 263-90.
21. Ballou WR, McClain JB, Gordon DM, et al. Safety and efficacy of highdose sodium stibogluconate therapy of American cutaneous leishmaniasis. Lancet 1987;2:13-6.
22. Navin TR, Arana BA, Arana FE, Berman JD, Chajón JF. Placebo-controlled clinical trial of sodium stibogluconate (Pentostam) versus ketoconazole for treating cutaneous leishmaniasis in Guatemala. J Infect Dis 1992;165:528-34.
23. Guderian RH, Chico ME, Rogers MD, Pattishall KM, Grogl M, Berman JD. Placebo controlled treatment of Ecuadorian cutaneous leishmaniasis. Am J Trop Med Hyg 1991;45:92-7.