DNA mismatch repair genes hMLH1, hMSH2, and hMSH6 are not inactivated in bronchioloalveolar carcinomas of the lung

Cancer

Volumn 92, Issue 11, 2001, Pages 2898-2901

  Aubry, Marie Christine ^a,b   Halling, Kevin C ^a   Myers, Jeffrey L ^a   Tazelaar, Henry D ^a   Yang, Ping ^a   Thibodeau, Stephen N ^a  

^a MAYO CLINIC   (United States)

^b Department of Laboratory Medicine and Pathology ^*  (United States)

Author keywords

Bronchioloalveolar carcinoma; Hereditary nonpolyposis colorectal carcinomas; Immunohistochemistry; Microsatellite instability; Mismatch repair genes

Indexed keywords

ADULT; AGED; ARTICLE; BASE MISPAIRING; CARCINOGENESIS; CLINICAL ARTICLE; FEMALE; GENE INACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS CELL CARCINOMA; MALE; MICROSATELLITE INSTABILITY; MUTATION; ONCOGENE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA, BRONCHIOLO-ALVEOLAR; AGED; AGED, 80 AND OVER; BASE PAIR MISMATCH; CARRIER PROTEINS; DNA REPAIR; DNA-BINDING PROTEINS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUTS HOMOLOG 2 PROTEIN; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS;

EID: 0035575736     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0142(20011201)92:11<2898::AID-CNCR10104>3.0.CO;2-Q     Document Type: Article

References (25)

1. Eukaryotic DNA mismatch repair
2. Many mutations in cancers
3. Genomic instability in neoplasia
4. Microsatellite instability and the role of hMSH2 in sporadic colorectal cancer
5. Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancer
6. A century of progress in hereditary nonpolyposis colorectal cancer (Lynch syndrome)
7. Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes
8. A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
9. Immunohistochemistry for hMLH1 and hMSH2: A practical test for DNA mismatch repair-deficient tumors
10. Microsatellite instability in human solid tumors
11. Origin of microsatellite instability in gastric cancer
12. Microsatellite instability is associated with tumors that characterize hereditary non-polyposis colorectal carcinoma syndrome
13. Microsatellite instability and other molecular abnormalities in non-small cell lung cancer
14. Frequent microsatellite instability in primary small cell lung cancer
15. Genetic instability of microsatellite sequences in many non-small cell lung carcinomas
16. Bronchoalveolar carcinomas: Factors affecting survival
17. Bronchoalveolar carcinoma: Histopathologic study of evolution in a series of 105 surgically treated patients
18. Bronchioloalveolar carcinomas. Cell types, patterns, and prognostic correlates
19. Microsatellite instability and MLH1 and MSH2 germline defects are related to clinicopathologic features in sporadic colorectal cancer
20. Tumor in microsatellite instability and clinical outcome in young patients with colorectal cancer
21. Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features
22. Immunohistochemical analysis for hMLH1 and hMSH2 expression in colorectal cancer
23. Microsatellite instability and hMLH1/ hMSH2 expression in young endometrial carcinoma patients: Associations with family history and histopathology
24. Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers