Gene transfer and metabolic modulators as new therapies for pulmonary hypertension: Increasing expression and activity of potassium channels in rat and human models

Advances in Experimental Medicine and Biology

Volumn 502, Issue , 2001, Pages 401-418

  Michelakis, Evangelos D ^a   Dyck, Jason R B ^a   McMurtry, M Sean ^a   Wang, Shaohua ^a   Wu, Xi Chen ^a   Moudgil, Rohit ^a   Hashimoto, Kyoko ^a   Puttagunta, Lakshmi ^a   Archer, Stephen L ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Adenovirus gene therapy; Dichloroacetate and metabolic modulators; Kv1.5; Kv2.1; Redox state

Indexed keywords

ADENOVIRUS VECTOR; DICHLOROACETIC ACID; ENZYME INHIBITOR; POTASSIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; CALCIUM CELL LEVEL; CELL MEMBRANE POTENTIAL; CELL PROLIFERATION; CHANNEL GATING; CONFERENCE PAPER; CONTROLLED STUDY; DEPOLARIZATION; DRUG MECHANISM; GENE TRANSFER; HEART RIGHT VENTRICLE HYPERTROPHY; HEMODYNAMIC MONITORING; HUMAN; HUMAN TISSUE; LUNG VASCULAR RESISTANCE; MALE; METABOLIC REGULATION; NONHUMAN; OXIDATION REDUCTION REACTION; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT; SMOOTH MUSCLE FIBER;

ADENOVIRIDAE; ANIMALIA;

EID: 0035573059     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4757-3401-0_26     Document Type: Conference Paper

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