Catecholamines abrogate antimitogenic effects of 2-hydroxyestradiol on human aortic vascular smooth muscle cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 21, Issue 11, 2001, Pages 1745-1750

  Zacharia, Lefteris C ^a   Jackson, Edwin K ^a   Gillespie, Delbert G ^a   Dubey, Raghvendra K ^a  

^a UNIVERSITÄTSSPITAL ZÜRICH   (Switzerland)

Author keywords

Catechol estrogens; Estradiol; Menopause; Methoxyestradiol; Vascular remodeling

Indexed keywords

2 HYDROXYESTRADIOL; 2 METHOXYESTRADIOL; ADRENALIN; ANTIMITOTIC AGENT; CATECHOL METHYLTRANSFERASE; CATECHOLAMINE; COLLAGEN TYPE 1; ISOPRENALINE; NORADRENALIN; PHENTOLAMINE MESYLATE; PROPRANOLOL; QUERCETIN;

AORTA MEDIA; AORTA OCCLUSION; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DNA SYNTHESIS; DRUG METABOLISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEART PROTECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; METHYLATION; PRIORITY JOURNAL;

EID: 0035569960     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/hq1001.097064     Document Type: Article

References (21)

1. Protective effects of estrogen on the cardiovascular and renal systems: Potential cellular, biochemical and molecular mechanisms
2. Estrogen inhibits the vascular injury response in estrogen receptor alpha-deficient mice
3. Estrogen inhibits the vascular injury response in estrogen receptor beta-deficient female mice
4. Methoxyestradiols mediate the antimitogenic effects of estradiol on vascular smooth muscle cells via estrogen receptor independent mechanisms
5. Estrogen and tamoxifen metabolites protect smooth muscle cell membrane phospholipids against peroxidation and inhibit cell growth
6. 17β-Estradiol, its metabolites, and progesterone inhibit cardiac fibroblast growth
7. Catechol-O-methyltransferase (COMT): Biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors
8. A possible role of catecholamines in atherogenesis and subsequent complications of atherosclerosis
9. Clinically used estrogens differentially inhibit human aortic smooth muscle cell growth and mitogen-activated protein kinase activity
10. Nitric oxide modulates basal and endothelin-induced coronary artery vascular smooth muscle cell proliferation and collagen levels
11. Increased 2-methoxyestradiol production in human coronary versus aortic vascular cells
12. Vascular effects of environmental oestrogens: Implications for reproductive and vascular health
13. Alpha 1-adrenergic stimulation and beta 2-adrenergic inhibition of DNA synthesis in vascular smooth muscle cells
14. Formation, metabolism, and physiologic importance of catecholestrogens
15. 125I-labelled ligand
16. The sympathetic nervous system in human hypertension
17. Pathophysiology of pheochromocytoma
18. The synaptic noradrenaline concentration in humans as estimated from simultaneous measurements of plasma noradrenaline and dihydroxyphenylglycol (DOPEG)
19. Differential effects of hormone-replacement therapy on endogenous nitric oxide (nitrate/nitrite) levels in postmenopausal women substituted with 17β-estradiol valerate and cyproterone acetate or medroxyprogesterone acetate
20. Antioxidant protection of LDL by physiological concentrations of 17β-estradiol: Requirement for estradiol modification
21. 4-Hydroxylation of estrogens as marker of human mammary tumors