Functional and morphological pattern of vascular responses in two models of experimental hypertension

Experimental and Clinical Cardiology

Volumn 6, Issue 3, 2001, Pages 142-148

  Török, Jozef ^a   Kristek, František ^a  

^a INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Arterial wall; Cardiac hypertrophy; Endothelium dependent relaxation; Hypertension; Morphometry

Indexed keywords

ACETYLCHOLINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PHENYLEPHRINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA INTIMA; AORTA MEDIA; ARTERY DIAMETER; BLOOD VESSEL REACTIVITY; BODY WEIGHT; CAROTID ARTERY; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG RESPONSE; DRUG SCREENING; ELECTRON MICROSCOPY; EXPERIMENTAL MODEL; HEART HYPERTROPHY; HEART WEIGHT; HYPERTENSION; ISOLATED ARTERY; MICROSCOPY; MORPHOLOGY; MORPHOMETRICS; NONHUMAN; PATHOLOGICAL ANATOMY; RAT; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; THICKNESS; THORACIC AORTA; VASCULAR RING;

EID: 0035569728     PISSN: 12056626     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (41)

1. Endothelium-dependent and independent relaxation of aortic rings from hypertensive rats
2. The loss of endothelium-dependent vascular relaxation in hypertension
3. A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation
4. Vascular superoxide production and vasomotor function in hypertension induced by deoxycorticosterone acetate-salt
5. Altered vasodilator and endothelium-dependent responses in hypertension
6. Dissociation of endothelial cell dysfunction and blood pressure in SHR
7. Impairment of endothelium-dependent dilatation of basilar artery during chronic hypertension
8. Vasodilation to acetylcholine in primary and secondary forms of human hypertension
9. Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension
10. Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat
11. Endothelium-dependent relaxation of hypertensive resistance arteries is not impaired under all conditions
12. Cardiac weight in hypertension induced by nitric oxide synthase blockade
13. Long-term nitric oxide synthase inhibition and distensibility of carotid artery in intact rats
14. Long-term NO synthase inhibition affects heart weight and geometry of coronary and carotid arteries
15. G-nitro-L-arginine methyl ester-induced hypertension. Novel molecular adaptation to systolic load in absence of hypertrophy
16. Vascular changes at the prehypertensive phase in the mesenteric arteries from spontaneously hypertensive rats
17. Vascular structural and functional alterations before and after the development of hypertension in SHR
18. Histamine-induced relaxation in pulmonary artery of normotensive and hypertensive rats: Relative contribution of prostanoids, nitric oxide and hyperpolarization
19. Long-term administration of L-arginine did not influence blood pressure, heart rate, cardiac hypertrophy or arterial wall thickness of spontaneously hypertensive rats
20. Chronic inhibition of nitric oxide synthesis. A new model of arterial hypertension
21. The vasodilatory effect of endogenous nitric oxide is a major counterregulatory mechanism in the spontaneously hypertensive rat
22. Changes in reactivity of pulmonary and systemic arteries in chronic NO-deficient hypertension
23. Chronic inhibition of NO synthesis produces myocardial and arterial media hyperplasia
24. Protein remodelling of the heart in NO deficient hypertension: The effect of captopril
25. Nitric oxide and its putative role in hypertension
26. Enhanced production of nitric oxide in aorta from spontaneously hypertensive rats by interleukin-1β
27. Unaltered endothelium-dependent modulation of contraction in the pulmonary artery of hypertensive rats
28. Physiological aspects of primary hypertension
29. Comparison of arterial wall, mechanics in normotensive and spontaneously hypertensive rats
30. Alterations in vascular smooth muscle mass in the spontaneously hypertensive rat. Role of cellular hypertrophy, hyperploidy, and hyperplasia
31. Persistent hypertension following inhibition of nitric oxide formation in the young Wistar rat: Role of renin and vascular hypertrophy
32. Remodelling of septal branch of coronary artery and carotid artery in L-NAME treated rats
33. Mechanism of structural remodelling of the rat aorta during long-term L-NAME treatment
34. Hyperplasia of vascular smooth muscle in experimental hypertension in the rabbit
35. Morphometry of medial hypertrophy in the rat thoracic aorta
36. Restriction of nitric oxide rather than elevated blood pressure is responsible for alterations of vascular responses in nitric oxide-deficient hypertension
37. Structural alterations of blood vessels in hypertensive rats
38. Small artery structure in hypertension. Dual process of remodelling and growth
39. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodelling
40. G-nitro-L-arginine methyl ester treatment does not prevent flow-induced remodelling in mesenteric feed arteries and arcading arteriols